Matches in SemOpenAlex for { <https://semopenalex.org/work/W3203986360> ?p ?o ?g. }
- W3203986360 endingPage "395" @default.
- W3203986360 startingPage "385" @default.
- W3203986360 abstract "CD79a and CD79b heterodimers are important components that consist of B cell receptor compound, which play a crucial role in transduction activation signal of the antigen binding BCR, and B cell development and antibody production. In order to investigate the characters and potential functions of CD79a and CD79b in rainbow trout (Oncorhynchus mykiss), we firstly cloned and analyzed the expression of CD79a and CD79b and found that the cDNA sequences of CD79a and CD79b both contained open reading frame of 711 and 645 bp in length for encoding the protein of 237 and 215 amino acid residues, respectively. The predicted amino acid sequences from trout were highly conserved with those of other teleost fishes in structure. Phylogenetic tree was constructed to analyze the evolutionary relationship between the trout and other known species, the result indicated that CD79a and CD79b of trout clustered at high bootstrap values with Salmo salar. Moreover, three trout infection models with F. columnare G4, I. multifiliis and infectious hematopoietic necrosis virus (IHNV) were constructed, which resulted in morphological changes and serious lesions in skin and gills. Importantly, the high expression of CD79a and CD79b occurred in skin, gills, and followed by head kidney in response to bacterial, parasitic, and viral infection, as its expression was closely related to that of Igs. Our findings indicated that CD79a and CD79b play vital roles in both systemic and mucosal immune responses of rainbow trout during bacterial, parasitic, and viral infection, which will contribute to explore the roles of CD79 subunits in B cell signaling during ontogeny and disease." @default.
- W3203986360 created "2021-10-11" @default.
- W3203986360 creator A5022144458 @default.
- W3203986360 creator A5027702659 @default.
- W3203986360 creator A5046466203 @default.
- W3203986360 creator A5074755331 @default.
- W3203986360 creator A5079278683 @default.
- W3203986360 creator A5083923547 @default.
- W3203986360 creator A5086162350 @default.
- W3203986360 date "2021-11-01" @default.
- W3203986360 modified "2023-10-17" @default.
- W3203986360 title "Molecular cloning and expression analysis of CD79a and CD79b in rainbow trout (Oncorhynchus mykiss) after bacterial, parasitic, and viral infection" @default.
- W3203986360 cites W1489418348 @default.
- W3203986360 cites W1794102914 @default.
- W3203986360 cites W1889200678 @default.
- W3203986360 cites W1966742362 @default.
- W3203986360 cites W1980339719 @default.
- W3203986360 cites W1981113451 @default.
- W3203986360 cites W1981307314 @default.
- W3203986360 cites W1982514550 @default.
- W3203986360 cites W1986484250 @default.
- W3203986360 cites W1989608676 @default.
- W3203986360 cites W1998361139 @default.
- W3203986360 cites W2030614680 @default.
- W3203986360 cites W2071818885 @default.
- W3203986360 cites W2077410229 @default.
- W3203986360 cites W2092915941 @default.
- W3203986360 cites W2093970486 @default.
- W3203986360 cites W2098490040 @default.
- W3203986360 cites W2126964023 @default.
- W3203986360 cites W2138142079 @default.
- W3203986360 cites W2143364298 @default.
- W3203986360 cites W2410940348 @default.
- W3203986360 cites W2510580204 @default.
- W3203986360 cites W2684687799 @default.
- W3203986360 cites W2738199796 @default.
- W3203986360 cites W2805720509 @default.
- W3203986360 cites W2895968160 @default.
- W3203986360 cites W2900957579 @default.
- W3203986360 cites W2908938113 @default.
- W3203986360 cites W2909394864 @default.
- W3203986360 cites W2936200043 @default.
- W3203986360 cites W2977788423 @default.
- W3203986360 cites W2991458961 @default.
- W3203986360 cites W3001247294 @default.
- W3203986360 cites W3088888168 @default.
- W3203986360 cites W3121289907 @default.
- W3203986360 doi "https://doi.org/10.1016/j.fsi.2021.09.022" @default.
- W3203986360 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34563671" @default.
- W3203986360 hasPublicationYear "2021" @default.
- W3203986360 type Work @default.
- W3203986360 sameAs 3203986360 @default.
- W3203986360 citedByCount "2" @default.
- W3203986360 countsByYear W32039863602022 @default.
- W3203986360 countsByYear W32039863602023 @default.
- W3203986360 crossrefType "journal-article" @default.
- W3203986360 hasAuthorship W3203986360A5022144458 @default.
- W3203986360 hasAuthorship W3203986360A5027702659 @default.
- W3203986360 hasAuthorship W3203986360A5046466203 @default.
- W3203986360 hasAuthorship W3203986360A5074755331 @default.
- W3203986360 hasAuthorship W3203986360A5079278683 @default.
- W3203986360 hasAuthorship W3203986360A5083923547 @default.
- W3203986360 hasAuthorship W3203986360A5086162350 @default.
- W3203986360 hasConcept C104317684 @default.
- W3203986360 hasConcept C161153951 @default.
- W3203986360 hasConcept C187882448 @default.
- W3203986360 hasConcept C2779363728 @default.
- W3203986360 hasConcept C2909208804 @default.
- W3203986360 hasConcept C2994167347 @default.
- W3203986360 hasConcept C505870484 @default.
- W3203986360 hasConcept C54355233 @default.
- W3203986360 hasConcept C86803240 @default.
- W3203986360 hasConcept C95444343 @default.
- W3203986360 hasConceptScore W3203986360C104317684 @default.
- W3203986360 hasConceptScore W3203986360C161153951 @default.
- W3203986360 hasConceptScore W3203986360C187882448 @default.
- W3203986360 hasConceptScore W3203986360C2779363728 @default.
- W3203986360 hasConceptScore W3203986360C2909208804 @default.
- W3203986360 hasConceptScore W3203986360C2994167347 @default.
- W3203986360 hasConceptScore W3203986360C505870484 @default.
- W3203986360 hasConceptScore W3203986360C54355233 @default.
- W3203986360 hasConceptScore W3203986360C86803240 @default.
- W3203986360 hasConceptScore W3203986360C95444343 @default.
- W3203986360 hasFunder F4320321001 @default.
- W3203986360 hasLocation W32039863601 @default.
- W3203986360 hasLocation W32039863602 @default.
- W3203986360 hasOpenAccess W3203986360 @default.
- W3203986360 hasPrimaryLocation W32039863601 @default.
- W3203986360 hasRelatedWork W1965841875 @default.
- W3203986360 hasRelatedWork W1968750438 @default.
- W3203986360 hasRelatedWork W2004982807 @default.
- W3203986360 hasRelatedWork W2036635417 @default.
- W3203986360 hasRelatedWork W2167576041 @default.
- W3203986360 hasRelatedWork W2230706134 @default.
- W3203986360 hasRelatedWork W2316047883 @default.
- W3203986360 hasRelatedWork W3183708469 @default.
- W3203986360 hasRelatedWork W4239897027 @default.
- W3203986360 hasRelatedWork W4249065314 @default.