Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204011947> ?p ?o ?g. }
- W3204011947 endingPage "10719" @default.
- W3204011947 startingPage "10719" @default.
- W3204011947 abstract "Gastric cancer (GC), with a heterogeneous nature, is the third leading cause of death worldwide. Over the past few decades, stable reductions in the incidence of GC have been observed. However, due to the poor response to common treatments and late diagnosis, this cancer is still considered one of the lethal cancers. Emerging methods such as immunotherapy with immune checkpoint inhibitors (ICIs) have transformed the landscape of treatment for GC patients. There are presently eleven known members of the B7 family as immune checkpoint molecules: B7-1 (CD80), B7-2 (CD86), B7-H1 (PD-L1, CD274), B7-DC (PDCD1LG2, PD-L2, CD273), B7-H2 (B7RP1, ICOS-L, CD275), B7-H3 (CD276), B7-H4 (B7x, B7S1, Vtcn1), B7-H5 (VISTA, Gi24, DD1α, Dies1 SISP1), B7-H6 (NCR3LG1), B7-H7 (HHLA2), and Ig-like domain-containing receptor 2 (ILDR2). Interaction of the B7 family of immune-regulatory ligands with the corresponding receptors resulted in the induction and inhibition of T cell responses by sending co-stimulatory and co-inhibitory signals, respectively. Manipulation of the signals provided by the B7 family has significant potential in the management of GC." @default.
- W3204011947 created "2021-10-11" @default.
- W3204011947 creator A5006117364 @default.
- W3204011947 creator A5008539877 @default.
- W3204011947 creator A5008839777 @default.
- W3204011947 creator A5051457623 @default.
- W3204011947 creator A5069031239 @default.
- W3204011947 creator A5074013977 @default.
- W3204011947 creator A5084692033 @default.
- W3204011947 creator A5086984759 @default.
- W3204011947 creator A5087525162 @default.
- W3204011947 creator A5089129517 @default.
- W3204011947 date "2021-10-03" @default.
- W3204011947 modified "2023-10-06" @default.
- W3204011947 title "The Positive and Negative Immunoregulatory Role of B7 Family: Promising Novel Targets in Gastric Cancer Treatment" @default.
- W3204011947 cites W1498454097 @default.
- W3204011947 cites W1506819618 @default.
- W3204011947 cites W1513619062 @default.
- W3204011947 cites W1520373882 @default.
- W3204011947 cites W1553363554 @default.
- W3204011947 cites W1564765245 @default.
- W3204011947 cites W1572739876 @default.
- W3204011947 cites W1738685314 @default.
- W3204011947 cites W1778360744 @default.
- W3204011947 cites W1816311090 @default.
- W3204011947 cites W1951816892 @default.
- W3204011947 cites W1963542131 @default.
- W3204011947 cites W1963688245 @default.
- W3204011947 cites W1965507670 @default.
- W3204011947 cites W1972346050 @default.
- W3204011947 cites W1983173932 @default.
- W3204011947 cites W1987628377 @default.
- W3204011947 cites W1989317719 @default.
- W3204011947 cites W1992184534 @default.
- W3204011947 cites W1994113933 @default.
- W3204011947 cites W1996891899 @default.
- W3204011947 cites W1999623709 @default.
- W3204011947 cites W1999843687 @default.
- W3204011947 cites W2000839918 @default.
- W3204011947 cites W2001630508 @default.
- W3204011947 cites W2008722061 @default.
- W3204011947 cites W2015836255 @default.
- W3204011947 cites W2017145792 @default.
- W3204011947 cites W2017606553 @default.
- W3204011947 cites W2018439447 @default.
- W3204011947 cites W2018562166 @default.
- W3204011947 cites W2024720815 @default.
- W3204011947 cites W2025360180 @default.
- W3204011947 cites W2028376975 @default.
- W3204011947 cites W2035918296 @default.
- W3204011947 cites W2038016611 @default.
- W3204011947 cites W2041560123 @default.
- W3204011947 cites W204284564 @default.
- W3204011947 cites W2046739604 @default.
- W3204011947 cites W2048670130 @default.
- W3204011947 cites W2048775478 @default.
- W3204011947 cites W2049784279 @default.
- W3204011947 cites W2051314511 @default.
- W3204011947 cites W2052644931 @default.
- W3204011947 cites W2053053955 @default.
- W3204011947 cites W2056021994 @default.
- W3204011947 cites W2056312577 @default.
- W3204011947 cites W2057499380 @default.
- W3204011947 cites W2057859692 @default.
- W3204011947 cites W2057893793 @default.
- W3204011947 cites W2066489069 @default.
- W3204011947 cites W2066730232 @default.
- W3204011947 cites W2068457469 @default.
- W3204011947 cites W2074342300 @default.
- W3204011947 cites W2075804595 @default.
- W3204011947 cites W2077226908 @default.
- W3204011947 cites W2077968480 @default.
- W3204011947 cites W2078843264 @default.
- W3204011947 cites W2081513802 @default.
- W3204011947 cites W2081816766 @default.
- W3204011947 cites W2093350337 @default.
- W3204011947 cites W2093613701 @default.
- W3204011947 cites W2093785165 @default.
- W3204011947 cites W2094548766 @default.
- W3204011947 cites W2097288420 @default.
- W3204011947 cites W2101338052 @default.
- W3204011947 cites W2105170173 @default.
- W3204011947 cites W2107556275 @default.
- W3204011947 cites W2110172571 @default.
- W3204011947 cites W2110836981 @default.
- W3204011947 cites W2114738239 @default.
- W3204011947 cites W2118471749 @default.
- W3204011947 cites W2118705059 @default.
- W3204011947 cites W2120550461 @default.
- W3204011947 cites W2121934915 @default.
- W3204011947 cites W2122639773 @default.
- W3204011947 cites W2130366224 @default.
- W3204011947 cites W2133125158 @default.
- W3204011947 cites W2134523831 @default.
- W3204011947 cites W2136648204 @default.
- W3204011947 cites W2137187071 @default.
- W3204011947 cites W2142291912 @default.
- W3204011947 cites W2147132132 @default.