FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204063718> ?p ?o ?g. }

• W3204063718 abstract "ABSTRACT Background Pandemics may promote hospital avoidance among patients with emergencies, and added precautions may exacerbate treatment delays. There is a paucity of population-based data on these phenomena for stroke. We examined the effect of the COVID-19 pandemic on the presentation and treatment of ischemic stroke in an entire population. Methods We used linked provincial administrative data and data from the Quality Improvement and Clinical Research Alberta Stroke Program – a registry capturing stroke-related data on the entire population of Alberta(4.3 million)– to identify all patients presenting with stroke in the pre-pandemic(1-January-2016 to 27-February-2020, n=19,531) and pandemic(28-February-2020 to 30-August-2020, n=2,255) periods. We examined changes in thrombolysis and endovascular therapy(EVT) rates, workflow, and in-hospital outcomes. Results Hospitalizations/presentations for ischemic stroke dropped (weekly adjusted-incidence-rate-ratio[aIRR]:0.48, 95%CI:0.46-0.50, adjusted for age, sex, comorbidities, pre-admission care needs), as did population-level incidence of thrombolysis(aIRR:0.49,0.44-0.56) or EVT(aIRR:0.59,0.49-0.69). However, the proportions of presenting patients receiving acute therapies did not decline (e.g. thrombolysis:11.7% pre-pandemic vs 13.1% during-pandemic, aOR:1.02,0.75-1.38). Onset-to-door times were prolonged; EVT recipients experienced longer door-to-reperfusion times (median door-to-reperfusion:110-minutes, IQR:77-156 pre-pandemic vs 132.5-minutes, 99-179 during-pandemic; adjusted-coefficient:18.7-minutes, 95%CI:1.45-36.0). Hospitalizations were shorter but stroke severity and in-hospital mortality did not differ. Interpretation The first COVID-19 wave was associated with a halving of presentations and acute therapy utilization for ischemic stroke at a population level, and greater pre-hospital and in-hospital treatment delays. Our data can inform public health messaging and stroke care in current and future waves. Messaging should encourage attendance for emergencies and stroke systems should re-examine “code stroke” protocols to mitigate inefficiencies." @default.
• W3204063718 created "2021-10-11" @default.
• W3204063718 creator A5010763268 @default.
• W3204063718 creator A5015783013 @default.
• W3204063718 creator A5027568070 @default.
• W3204063718 creator A5052668764 @default.
• W3204063718 creator A5056711512 @default.
• W3204063718 creator A5057812366 @default.
• W3204063718 creator A5075010536 @default.
• W3204063718 creator A5081968344 @default.
• W3204063718 date "2021-10-07" @default.
• W3204063718 modified "2023-10-06" @default.
• W3204063718 title "Changes in ischemic stroke presentations and associated workflow during the first wave of the COVID-19 pandemic: A population study in Alberta, Canada" @default.
• W3204063718 cites W1913037690 @default.
• W3204063718 cites W1993817112 @default.
• W3204063718 cites W1994584686 @default.
• W3204063718 cites W2066328889 @default.
• W3204063718 cites W2134722663 @default.
• W3204063718 cites W2171017045 @default.
• W3204063718 cites W2526978419 @default.
• W3204063718 cites W2535326255 @default.
• W3204063718 cites W2767776410 @default.
• W3204063718 cites W3011678644 @default.
• W3204063718 cites W3012930476 @default.
• W3204063718 cites W3013413864 @default.
• W3204063718 cites W3014892609 @default.
• W3204063718 cites W3016716567 @default.
• W3204063718 cites W3020954032 @default.
• W3204063718 cites W3028018957 @default.
• W3204063718 cites W3028576648 @default.
• W3204063718 cites W3028928563 @default.
• W3204063718 cites W3030925721 @default.
• W3204063718 cites W3033776099 @default.
• W3204063718 cites W3036618295 @default.
• W3204063718 cites W3036641605 @default.
• W3204063718 cites W3037073289 @default.
• W3204063718 cites W3044107695 @default.
• W3204063718 cites W3048360820 @default.
• W3204063718 cites W3093042762 @default.
• W3204063718 cites W3095121458 @default.
• W3204063718 cites W3101488739 @default.
• W3204063718 cites W3109123114 @default.
• W3204063718 cites W3109418069 @default.
• W3204063718 cites W3164087247 @default.
• W3204063718 doi "https://doi.org/10.1101/2021.10.04.21264529" @default.
• W3204063718 hasPublicationYear "2021" @default.
• W3204063718 type Work @default.
• W3204063718 sameAs 3204063718 @default.
• W3204063718 citedByCount "0" @default.
• W3204063718 crossrefType "posted-content" @default.
• W3204063718 hasAuthorship W3204063718A5010763268 @default.
• W3204063718 hasAuthorship W3204063718A5015783013 @default.
• W3204063718 hasAuthorship W3204063718A5027568070 @default.
• W3204063718 hasAuthorship W3204063718A5052668764 @default.
• W3204063718 hasAuthorship W3204063718A5056711512 @default.
• W3204063718 hasAuthorship W3204063718A5057812366 @default.
• W3204063718 hasAuthorship W3204063718A5075010536 @default.
• W3204063718 hasAuthorship W3204063718A5081968344 @default.
• W3204063718 hasBestOaLocation W32040637181 @default.
• W3204063718 hasConcept C120665830 @default.
• W3204063718 hasConcept C121332964 @default.
• W3204063718 hasConcept C126322002 @default.
• W3204063718 hasConcept C127413603 @default.
• W3204063718 hasConcept C194828623 @default.
• W3204063718 hasConcept C2779134260 @default.
• W3204063718 hasConcept C2779581417 @default.
• W3204063718 hasConcept C2780645631 @default.
• W3204063718 hasConcept C2908647359 @default.
• W3204063718 hasConcept C3008058167 @default.
• W3204063718 hasConcept C500558357 @default.
• W3204063718 hasConcept C524204448 @default.
• W3204063718 hasConcept C61511704 @default.
• W3204063718 hasConcept C71924100 @default.
• W3204063718 hasConcept C78519656 @default.
• W3204063718 hasConcept C89623803 @default.
• W3204063718 hasConcept C99454951 @default.
• W3204063718 hasConceptScore W3204063718C120665830 @default.
• W3204063718 hasConceptScore W3204063718C121332964 @default.
• W3204063718 hasConceptScore W3204063718C126322002 @default.
• W3204063718 hasConceptScore W3204063718C127413603 @default.
• W3204063718 hasConceptScore W3204063718C194828623 @default.
• W3204063718 hasConceptScore W3204063718C2779134260 @default.
• W3204063718 hasConceptScore W3204063718C2779581417 @default.
• W3204063718 hasConceptScore W3204063718C2780645631 @default.
• W3204063718 hasConceptScore W3204063718C2908647359 @default.
• W3204063718 hasConceptScore W3204063718C3008058167 @default.
• W3204063718 hasConceptScore W3204063718C500558357 @default.
• W3204063718 hasConceptScore W3204063718C524204448 @default.
• W3204063718 hasConceptScore W3204063718C61511704 @default.
• W3204063718 hasConceptScore W3204063718C71924100 @default.
• W3204063718 hasConceptScore W3204063718C78519656 @default.
• W3204063718 hasConceptScore W3204063718C89623803 @default.
• W3204063718 hasConceptScore W3204063718C99454951 @default.
• W3204063718 hasLocation W32040637181 @default.
• W3204063718 hasOpenAccess W3204063718 @default.
• W3204063718 hasPrimaryLocation W32040637181 @default.
• W3204063718 hasRelatedWork W1989098122 @default.
• W3204063718 hasRelatedWork W2003996048 @default.
• W3204063718 hasRelatedWork W2049485678 @default.
• W3204063718 hasRelatedWork W2135244516 @default.

• next