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- W3204068375 startingPage "367" @default.
- W3204068375 abstract "Oleaeuropea L. commonly known as olive tree has immense health benefits. Traditionally it is used to treat different pathologies such as olive leaves used against coughing, cystitis and sore throat, cardiovascular diseases, mouth cleanser, dried leaves and fruits of olive tree in gastrointestinal problems (diarrhea) and urinary tract infections, hypertension, asthma, and most importantly cancer. The phytochemical analysis revealed rich phytochemical composition of the plant and led to the isolation of more than hundred different compounds, such as flavonoids, biophenols, and terpenoids such as iridoids, secoiridoids, triterpenoids, coumarin.Similarly, olive leaf possessed a strong bioactive composition with a high concentration of oleuropein (glycosylated secoiridoid). Similarly, olive leaf possessed a strong bioactive composition with a high concentration of oleuropein (glycosylated secoiridoid). The leaf extracts and its derivative compounds have shown potent anticancer effects against different cell lines in different organs. These compounds include oleuropein, maslinic acid, erythrodiol, uvaol, oleanolic acid, hydroxytyrosol, tyrosol. Among others Oleuropein and its derivative compounds (hydroxytyrosol, tyrosol and others) were studied in a several types of cancer cells. In fact, many studies have demonstrated the oleuropein and its derivative have proved pharmacological activity against proliferation of cancer cells and several tumor cell lines by different mechanisms such arrest cell cycle and cause apoptosis in cancerous cells, by modulation of miRNA expression and upregulation and downregulation of several genes. This chapter deals with the anticancer effect exert by O. europaea leaf constituents and its possible anticancer mechanism." @default.
- W3204068375 created "2021-10-11" @default.
- W3204068375 creator A5012591023 @default.
- W3204068375 creator A5039882022 @default.
- W3204068375 creator A5055882510 @default.
- W3204068375 creator A5085120624 @default.
- W3204068375 date "2021-01-01" @default.
- W3204068375 modified "2023-09-26" @default.
- W3204068375 title "Olive Leaf (Oleuropein) and Its Role in Cancer: Therapeutic Updates" @default.
- W3204068375 cites W1544860636 @default.
- W3204068375 cites W1599362861 @default.
- W3204068375 cites W1634080553 @default.
- W3204068375 cites W1863082270 @default.
- W3204068375 cites W1963876824 @default.
- W3204068375 cites W1965112011 @default.
- W3204068375 cites W1965778553 @default.
- W3204068375 cites W1966020857 @default.
- W3204068375 cites W1966296314 @default.
- W3204068375 cites W1967982356 @default.
- W3204068375 cites W1968449539 @default.
- W3204068375 cites W1968659809 @default.
- W3204068375 cites W1970154946 @default.
- W3204068375 cites W1972394943 @default.
- W3204068375 cites W1973717075 @default.
- W3204068375 cites W1974822130 @default.
- W3204068375 cites W1976174965 @default.
- W3204068375 cites W1977112558 @default.
- W3204068375 cites W1978175145 @default.
- W3204068375 cites W1981262353 @default.
- W3204068375 cites W1984306736 @default.
- W3204068375 cites W1986012467 @default.
- W3204068375 cites W1986110470 @default.
- W3204068375 cites W1986752093 @default.
- W3204068375 cites W1992045933 @default.
- W3204068375 cites W1996006045 @default.
- W3204068375 cites W1998850675 @default.
- W3204068375 cites W1998887711 @default.
- W3204068375 cites W2004515155 @default.
- W3204068375 cites W2005170572 @default.
- W3204068375 cites W2007185373 @default.
- W3204068375 cites W2009003493 @default.
- W3204068375 cites W2009672285 @default.
- W3204068375 cites W2012450448 @default.
- W3204068375 cites W2012997934 @default.
- W3204068375 cites W2014224712 @default.
- W3204068375 cites W2015466129 @default.
- W3204068375 cites W2015799649 @default.
- W3204068375 cites W2017148342 @default.
- W3204068375 cites W2017803673 @default.
- W3204068375 cites W2018333108 @default.
- W3204068375 cites W2018337880 @default.
- W3204068375 cites W2020141487 @default.
- W3204068375 cites W2020430786 @default.
- W3204068375 cites W2020469696 @default.
- W3204068375 cites W2021624913 @default.
- W3204068375 cites W2023536393 @default.
- W3204068375 cites W2024839865 @default.
- W3204068375 cites W2026065943 @default.
- W3204068375 cites W2026569432 @default.
- W3204068375 cites W2033236942 @default.
- W3204068375 cites W2033806492 @default.
- W3204068375 cites W2035933301 @default.
- W3204068375 cites W2037504970 @default.
- W3204068375 cites W2037742489 @default.
- W3204068375 cites W2040497173 @default.
- W3204068375 cites W2041237128 @default.
- W3204068375 cites W2046424185 @default.
- W3204068375 cites W2048165009 @default.
- W3204068375 cites W2048580007 @default.
- W3204068375 cites W2048884984 @default.
- W3204068375 cites W2049620158 @default.
- W3204068375 cites W2053571022 @default.
- W3204068375 cites W2053685416 @default.
- W3204068375 cites W2054363788 @default.
- W3204068375 cites W2054452567 @default.
- W3204068375 cites W2055778829 @default.
- W3204068375 cites W2056109880 @default.
- W3204068375 cites W2057167574 @default.
- W3204068375 cites W2057572583 @default.
- W3204068375 cites W2058087337 @default.
- W3204068375 cites W2061082165 @default.
- W3204068375 cites W2061466360 @default.
- W3204068375 cites W2062142761 @default.
- W3204068375 cites W2063176116 @default.
- W3204068375 cites W2065070740 @default.
- W3204068375 cites W2066089664 @default.
- W3204068375 cites W2066786994 @default.
- W3204068375 cites W2074038299 @default.
- W3204068375 cites W2074299448 @default.
- W3204068375 cites W2075041427 @default.
- W3204068375 cites W2076033489 @default.
- W3204068375 cites W2076110748 @default.
- W3204068375 cites W2076620871 @default.
- W3204068375 cites W2076903805 @default.
- W3204068375 cites W2078253837 @default.
- W3204068375 cites W2078905668 @default.
- W3204068375 cites W2081212046 @default.
- W3204068375 cites W2081761148 @default.