FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204100810> ?p ?o ?g. }

• W3204100810 endingPage "842" @default.
• W3204100810 startingPage "838" @default.
• W3204100810 abstract "Background/Aim: Thyroid hormones play an essential role in retinal development and physiological functions. Although the effects of hyperthyroidism on ocular circulation are well-defined, no studies report the effects of clinical hypothyroidism on retinal and choroidal circulation. We aimed to compare the macular vessel density and flow indexes of patients with treatment-naive hypothyroidism and healthy controls using optical coherence tomography angiography (OCTA). Methods: This case-control study included 104 eyes of 52 participants. Group 1 (n=24) consisted of patients with treatment-naive overt hypothyroidism, while Group 2 (n=28) consisted of age and sex-matched healthy controls. Images were obtained using AngioVue software 2.0 of the OCTA device in a 6 × 6 mm area centered on the macula. Foveal avascular zone (FAZ) area, macular retinal thickness, FAZ perimeter (PERIM), choroidal flow index (CF), outer retinal flow index (ORF) and macular vessel density (VD) in the superficial (SCP) and deep retinal capillary plexus (DCP) were recorded for all patients. Results: The whole [Group 1: 49.9 (7.0)%; Group 2: 54.6 (5.9)%], parafoveal [Group 1: 54.7 (4.8)%; Group 2: 58.6 (3.9)%] and perifoveal [Group 1: 51.5 (7.2)%; Group 2: 55.9 (6.8)% ] VD in DCP were significantly lower in Group 1 compared to Group 2 (P=0.012; P=0.002 and P=0.028 respectively). However, parafoveal VD in SCP was significantly higher in Group 1 [52.4 (2.26)] than in Group 2 [49.9 (6.87)] (P=0.032). The mean VD in DCP was significantly positively correlated with the choroidal (P=0.021) and outer retinal flow indexes (P=0.033). The mean foveal VD in DCP was significantly positively correlated with the mean foveal (P<0.001), parafoveal (P=0.001) and perifoveal retinal thicknesses (P<0.001). Conclusion: Our study has provided, for the first time, a quantitative assessment of macular perfusion in patients with overt hypothyroidism using OCTA. The reduction in VD in the DCP might be attributed to the lack of angiogenic effects of T4 or neural hypometabolism secondary to hypothyroidism." @default.
• W3204100810 created "2021-10-11" @default.
• W3204100810 creator A5010404669 @default.
• W3204100810 creator A5030343860 @default.
• W3204100810 creator A5032044196 @default.
• W3204100810 creator A5065087516 @default.
• W3204100810 creator A5080099846 @default.
• W3204100810 date "2021-09-01" @default.
• W3204100810 modified "2023-10-14" @default.
• W3204100810 title "Evaluation of macular perfusion in patients with treatment-naive overt hypothyroidism using optical coherence tomography angiography" @default.
• W3204100810 cites W126069483 @default.
• W3204100810 cites W1485977784 @default.
• W3204100810 cites W1972980385 @default.
• W3204100810 cites W1995896527 @default.
• W3204100810 cites W2003962662 @default.
• W3204100810 cites W2018396038 @default.
• W3204100810 cites W2024335139 @default.
• W3204100810 cites W2024592965 @default.
• W3204100810 cites W2029988976 @default.
• W3204100810 cites W2039159224 @default.
• W3204100810 cites W2041444259 @default.
• W3204100810 cites W2043015190 @default.
• W3204100810 cites W2050068253 @default.
• W3204100810 cites W2055674903 @default.
• W3204100810 cites W2057923087 @default.
• W3204100810 cites W2092262801 @default.
• W3204100810 cites W2105467159 @default.
• W3204100810 cites W2118978221 @default.
• W3204100810 cites W2124173888 @default.
• W3204100810 cites W2124374523 @default.
• W3204100810 cites W2134364768 @default.
• W3204100810 cites W2140936682 @default.
• W3204100810 cites W2146874310 @default.
• W3204100810 cites W2150746400 @default.
• W3204100810 cites W2344015286 @default.
• W3204100810 cites W2587570425 @default.
• W3204100810 cites W2613174633 @default.
• W3204100810 cites W2735146293 @default.
• W3204100810 cites W2775636951 @default.
• W3204100810 cites W2793741017 @default.
• W3204100810 cites W2891538960 @default.
• W3204100810 cites W2943480267 @default.
• W3204100810 cites W2954885493 @default.
• W3204100810 cites W2969669215 @default.
• W3204100810 cites W2996346625 @default.
• W3204100810 cites W3005817113 @default.
• W3204100810 doi "https://doi.org/10.28982/josam.963002" @default.
• W3204100810 hasPublicationYear "2021" @default.
• W3204100810 type Work @default.
• W3204100810 sameAs 3204100810 @default.
• W3204100810 citedByCount "1" @default.
• W3204100810 countsByYear W32041008102023 @default.
• W3204100810 crossrefType "journal-article" @default.
• W3204100810 hasAuthorship W3204100810A5010404669 @default.
• W3204100810 hasAuthorship W3204100810A5030343860 @default.
• W3204100810 hasAuthorship W3204100810A5032044196 @default.
• W3204100810 hasAuthorship W3204100810A5065087516 @default.
• W3204100810 hasAuthorship W3204100810A5080099846 @default.
• W3204100810 hasBestOaLocation W32041008101 @default.
• W3204100810 hasConcept C118487528 @default.
• W3204100810 hasConcept C126322002 @default.
• W3204100810 hasConcept C146957229 @default.
• W3204100810 hasConcept C2780248432 @default.
• W3204100810 hasConcept C2780827179 @default.
• W3204100810 hasConcept C2985858981 @default.
• W3204100810 hasConcept C71924100 @default.
• W3204100810 hasConceptScore W3204100810C118487528 @default.
• W3204100810 hasConceptScore W3204100810C126322002 @default.
• W3204100810 hasConceptScore W3204100810C146957229 @default.
• W3204100810 hasConceptScore W3204100810C2780248432 @default.
• W3204100810 hasConceptScore W3204100810C2780827179 @default.
• W3204100810 hasConceptScore W3204100810C2985858981 @default.
• W3204100810 hasConceptScore W3204100810C71924100 @default.
• W3204100810 hasIssue "9" @default.
• W3204100810 hasLocation W32041008101 @default.
• W3204100810 hasOpenAccess W3204100810 @default.
• W3204100810 hasPrimaryLocation W32041008101 @default.
• W3204100810 hasRelatedWork W1593038791 @default.
• W3204100810 hasRelatedWork W2084530301 @default.
• W3204100810 hasRelatedWork W2805767801 @default.
• W3204100810 hasRelatedWork W2808246028 @default.
• W3204100810 hasRelatedWork W2921264217 @default.
• W3204100810 hasRelatedWork W3039290057 @default.
• W3204100810 hasRelatedWork W3186122943 @default.
• W3204100810 hasRelatedWork W3206108945 @default.
• W3204100810 hasRelatedWork W4385074306 @default.
• W3204100810 hasRelatedWork W3041362231 @default.
• W3204100810 hasVolume "5" @default.
• W3204100810 isParatext "false" @default.
• W3204100810 isRetracted "false" @default.
• W3204100810 magId "3204100810" @default.
• W3204100810 workType "article" @default.