FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204102482> ?p ?o ?g. }

• W3204102482 abstract "Pharmacology is essentially an interdisciplinary science. As such, knowledge gained in several different areas is gathered to focus on human health. Although South America is a region ravaged by multiple political and economic conflicts throughout its history, cell biology and pharmacological studies were conducted by many South American outstanding researchers working in their own countries and abroad. On the region, Argentine has a privileged history, including Bernardo Houssay, who was awarded the Nobel Prize in Physiology and Medicine in 1947 for his work on pituitary hormones1; Luis F. Leloir, who was awarded the Nobel Prize in Chemistry in 1970 for his research on glycogen metabolism2; Eduardo Braun-Menendez, who was one of the discoverers of angiotensin3; Adolfo J. De Bold, who discovered atrial natriuretic factor,4 and a team that made a great contribution that was pivotal for understanding the presynaptic regulation of neurotransmitter release.5, 6 All these exceptional researchers and their contributions helped to establish an Argentinean pharmacological tradition that still has a strong influence nowadays. Almost 30% of all researchers recruited by the most important scientific national organism (CONICET) are involved only in biomedical research. Unfortunately, projects and scientific careers in South America are often finished or significantly delayed because of adverse social conditions, political turmoil, and economic collapses. Unhappily, this has been recurrent in most of our countries and a constant in the region. Nevertheless, there is a pharmacological tradition that continues producing exceptional work contributing to our current knowledge. When economic constraints and infrastructure issues are constant, you are forced to harness your imagination and creativity and make the most of them. This special issue features articles written by a selected group of leading South American scientists working on different aspects of pharmacology who share the passion for knowledge and use their inspiration to search for alternatives making the most of their budgets and compensating the shortages with innovation. The common thread of the articles comprised by this issue is the exploration of options or alternative uses for well-established compounds or systems. With resource optimization as their motivation, Gorzalczany et al.7 wrote an article discussing potential substitutes for the use of experimental animals, Giunti et al.8 consider the use of a simple and economic platform based on nematodes for drug discovery, and Nuske et al.9 explore the application of algorithms and computer simulations to optimize and reduce bioequivalence studies. On the other hand, examining alternatives for the treatment of well-studied pathological situations, Nader et al.10 study the use of probiotics in hygienic products for the treatment of female urogenital tract infections, Schofs et al.11 discuss the antimicrobial effects of Cannabis sativa against fungus and pathogenic bacteria to assess its potential use as an antimicrobial agent, and Formica et al.12 report the benefits of novel nanoparticles for the delivery of anti-vascular endothelial growth factor agents for ocular angiogenesis. Finally, exploring the complexity of some conditions that require innovative approaches, Palumbo et al.13 explore how immunomodulation by neuropeptides can be a valid strategy for the treatment of neurodegenerative disorders, and Sarasola et al.14 investigate the immunomodulatory roles of histamine for cancer treatment. In summary, this special issue of Pharmacology Research & Perspectives will provide an outlook of the current research in South America, hoping that readers will find the articles to be of interest and that help promote collaboration with colleagues in other parts of the world." @default.
• W3204102482 created "2021-10-11" @default.
• W3204102482 creator A5039686693 @default.
• W3204102482 creator A5066083078 @default.
• W3204102482 date "2021-10-01" @default.
• W3204102482 modified "2023-10-08" @default.
• W3204102482 title "South American special issue: Editorial" @default.
• W3204102482 cites W2092183051 @default.
• W3204102482 cites W2121815042 @default.
• W3204102482 cites W2901149630 @default.
• W3204102482 cites W3133991926 @default.
• W3204102482 cites W3134273682 @default.
• W3204102482 cites W3141935721 @default.
• W3204102482 cites W3203247534 @default.
• W3204102482 cites W3203396349 @default.
• W3204102482 cites W3204545714 @default.
• W3204102482 cites W3204613200 @default.
• W3204102482 doi "https://doi.org/10.1002/prp2.868" @default.
• W3204102482 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8491458" @default.
• W3204102482 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34609071" @default.
• W3204102482 hasPublicationYear "2021" @default.
• W3204102482 type Work @default.
• W3204102482 sameAs 3204102482 @default.
• W3204102482 citedByCount "0" @default.
• W3204102482 crossrefType "journal-article" @default.
• W3204102482 hasAuthorship W3204102482A5039686693 @default.
• W3204102482 hasAuthorship W3204102482A5066083078 @default.
• W3204102482 hasBestOaLocation W32041024821 @default.
• W3204102482 hasConcept C138885662 @default.
• W3204102482 hasConcept C17744445 @default.
• W3204102482 hasConcept C199539241 @default.
• W3204102482 hasConcept C71924100 @default.
• W3204102482 hasConcept C94625758 @default.
• W3204102482 hasConcept C95124753 @default.
• W3204102482 hasConceptScore W3204102482C138885662 @default.
• W3204102482 hasConceptScore W3204102482C17744445 @default.
• W3204102482 hasConceptScore W3204102482C199539241 @default.
• W3204102482 hasConceptScore W3204102482C71924100 @default.
• W3204102482 hasConceptScore W3204102482C94625758 @default.
• W3204102482 hasConceptScore W3204102482C95124753 @default.
• W3204102482 hasIssue "5" @default.
• W3204102482 hasLocation W32041024821 @default.
• W3204102482 hasLocation W32041024822 @default.
• W3204102482 hasLocation W32041024823 @default.
• W3204102482 hasLocation W32041024824 @default.
• W3204102482 hasOpenAccess W3204102482 @default.
• W3204102482 hasPrimaryLocation W32041024821 @default.
• W3204102482 hasRelatedWork W2322233747 @default.
• W3204102482 hasRelatedWork W2360957661 @default.
• W3204102482 hasRelatedWork W2479372671 @default.
• W3204102482 hasRelatedWork W2748952813 @default.
• W3204102482 hasRelatedWork W2899084033 @default.
• W3204102482 hasRelatedWork W3031052312 @default.
• W3204102482 hasRelatedWork W3143263336 @default.
• W3204102482 hasRelatedWork W4231938959 @default.
• W3204102482 hasRelatedWork W4247937600 @default.
• W3204102482 hasRelatedWork W2167468920 @default.
• W3204102482 hasVolume "9" @default.
• W3204102482 isParatext "false" @default.
• W3204102482 isRetracted "false" @default.
• W3204102482 magId "3204102482" @default.
• W3204102482 workType "article" @default.