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• W3204103139 abstract "To clarify the association between systemic and hepatic inflammation and localized periodontitis which has been reported to vary among races.The study included 1112 military males, aged 18-40 years, in Taiwan. Participants were classified as periodontally healthy/stage I (n = 796) or stage II/III periodontitis (n = 316), according to the 2017 world workshop criteria. Systemic and hepatic inflammation were defined by the highest tertiles of blood leukocyte counts (7.51 × 103 /μl) and alanine aminotransferase (30 U/L), respectively. Multiple logistic regression analysis with adjustments for age, metabolic syndrome, betel nut consumption and smoking was carried out.There was a significant association between high systemic inflammation, irrespective of hepatic inflammation severity, and localized stage II/III periodontitis (odds ratio [OR], 1.62 [1.09-2.42] and 1.47 [1.00-2.15], respectively, in the presence of high or no hepatic inflammation. However, no significant association was found among participants with low systemic inflammation, irrespective of the severity of hepatic inflammation (OR, 1.31 [0.91-1.91]).An association between hepatic inflammation and localized periodontitis in Taiwanese was observed only if systemic inflammation coexisted, possibly accounting for the reported differences in the association between Japanese and non-Asian populations in prior studies." @default.
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• W3204103139 date "2021-10-05" @default.
• W3204103139 modified "2023-10-16" @default.
• W3204103139 title "Association of hepatic and systemic inflammation with localized stage <scp>II</scp> / <scp>III</scp> periodontitis in young males: The <scp>CHIEF</scp> oral health study" @default.
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• W3204103139 doi "https://doi.org/10.1111/jcpe.13556" @default.
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