FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204104051> ?p ?o ?g. }

• W3204104051 abstract "Introduction Haemophilia is a bleeding disorder that occurs due to the deficiency of coagulation factors, and the angiogenesis process is an important process underlying the pathophysiology of haemophilic arthropathy. The role of the new adipocytokine endoglin (ENG) in patients with haemophilia is not yet known. Aim The aim of this study is to evaluate the association between ENG protein and angiogenesis‐related cytokines in patients with haemophilia for the first time. Methods Plasma protein levels and mRNA expressions of ENG and various angiogenesis‐associated cytokines were compared in blood samples collected from 28 patients with haemophilia A or B and 29 healthy volunteers. The relationship between the cytokines and ENG were determined by correlation analysis. Results Plasma ENG levels and angiogenic markers were found to be significantly higher in patients with haemophilia compared to controls. Real‐time PCR studies showed that mRNA expressions of ENG, vascular endothelial growth factor A, hypoxia‐inducible factor A, and prostaglandin E2 increased in patients with haemophilia. Correlation analysis showed a significant positive correlation between ENG and angiopoietin‐2 levels in the haemophilia group. Besides, a significant decrease in annexin‐V binding to platelets in haemophilia patients compared to control was found to be related to the bleeding profiles in the patients. Conclusions This study determined that ENG protein may be involved in the formation of angiogenesis in haemophilia patients and its effects may be related to angiogenetic marker angiopoietin‐2 in this process. Our findings contribute to the literature during the determination of target proteins in haemophilia treatment." @default.
• W3204104051 created "2021-10-11" @default.
• W3204104051 creator A5003953342 @default.
• W3204104051 creator A5042622002 @default.
• W3204104051 creator A5054028405 @default.
• W3204104051 creator A5075042006 @default.
• W3204104051 date "2021-10-06" @default.
• W3204104051 modified "2023-10-05" @default.
• W3204104051 title "Increased endoglin levels correlated with angiogenesis‐associated angiopoietin‐2 in haemophilia patients" @default.
• W3204104051 cites W1519535724 @default.
• W3204104051 cites W1551404437 @default.
• W3204104051 cites W1569127781 @default.
• W3204104051 cites W1608726413 @default.
• W3204104051 cites W1887346136 @default.
• W3204104051 cites W1974514897 @default.
• W3204104051 cites W1986681637 @default.
• W3204104051 cites W1987169447 @default.
• W3204104051 cites W1988349955 @default.
• W3204104051 cites W1997443499 @default.
• W3204104051 cites W2005158748 @default.
• W3204104051 cites W2043834774 @default.
• W3204104051 cites W2044466245 @default.
• W3204104051 cites W2046223728 @default.
• W3204104051 cites W2055851568 @default.
• W3204104051 cites W2060801600 @default.
• W3204104051 cites W2062455594 @default.
• W3204104051 cites W2068581036 @default.
• W3204104051 cites W2068588711 @default.
• W3204104051 cites W2088244043 @default.
• W3204104051 cites W2110724503 @default.
• W3204104051 cites W2116833132 @default.
• W3204104051 cites W2120279581 @default.
• W3204104051 cites W2145213708 @default.
• W3204104051 cites W2149982213 @default.
• W3204104051 cites W2329948262 @default.
• W3204104051 cites W2403540161 @default.
• W3204104051 cites W2413075460 @default.
• W3204104051 cites W2566451940 @default.
• W3204104051 cites W2765199942 @default.
• W3204104051 cites W2792116003 @default.
• W3204104051 cites W2884506035 @default.
• W3204104051 cites W292647304 @default.
• W3204104051 cites W3003816282 @default.
• W3204104051 doi "https://doi.org/10.1111/hae.14430" @default.
• W3204104051 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34614537" @default.
• W3204104051 hasPublicationYear "2021" @default.
• W3204104051 type Work @default.
• W3204104051 sameAs 3204104051 @default.
• W3204104051 citedByCount "3" @default.
• W3204104051 countsByYear W32041040512023 @default.
• W3204104051 crossrefType "journal-article" @default.
• W3204104051 hasAuthorship W3204104051A5003953342 @default.
• W3204104051 hasAuthorship W3204104051A5042622002 @default.
• W3204104051 hasAuthorship W3204104051A5054028405 @default.
• W3204104051 hasAuthorship W3204104051A5075042006 @default.
• W3204104051 hasConcept C10205521 @default.
• W3204104051 hasConcept C126322002 @default.
• W3204104051 hasConcept C141071460 @default.
• W3204104051 hasConcept C167734588 @default.
• W3204104051 hasConcept C203014093 @default.
• W3204104051 hasConcept C2776719180 @default.
• W3204104051 hasConcept C2777025900 @default.
• W3204104051 hasConcept C2777232031 @default.
• W3204104051 hasConcept C2778385053 @default.
• W3204104051 hasConcept C2779094623 @default.
• W3204104051 hasConcept C2780394083 @default.
• W3204104051 hasConcept C28328180 @default.
• W3204104051 hasConcept C54355233 @default.
• W3204104051 hasConcept C6061869 @default.
• W3204104051 hasConcept C71924100 @default.
• W3204104051 hasConcept C86803240 @default.
• W3204104051 hasConcept C90924648 @default.
• W3204104051 hasConceptScore W3204104051C10205521 @default.
• W3204104051 hasConceptScore W3204104051C126322002 @default.
• W3204104051 hasConceptScore W3204104051C141071460 @default.
• W3204104051 hasConceptScore W3204104051C167734588 @default.
• W3204104051 hasConceptScore W3204104051C203014093 @default.
• W3204104051 hasConceptScore W3204104051C2776719180 @default.
• W3204104051 hasConceptScore W3204104051C2777025900 @default.
• W3204104051 hasConceptScore W3204104051C2777232031 @default.
• W3204104051 hasConceptScore W3204104051C2778385053 @default.
• W3204104051 hasConceptScore W3204104051C2779094623 @default.
• W3204104051 hasConceptScore W3204104051C2780394083 @default.
• W3204104051 hasConceptScore W3204104051C28328180 @default.
• W3204104051 hasConceptScore W3204104051C54355233 @default.
• W3204104051 hasConceptScore W3204104051C6061869 @default.
• W3204104051 hasConceptScore W3204104051C71924100 @default.
• W3204104051 hasConceptScore W3204104051C86803240 @default.
• W3204104051 hasConceptScore W3204104051C90924648 @default.
• W3204104051 hasIssue "6" @default.
• W3204104051 hasLocation W32041040511 @default.
• W3204104051 hasLocation W32041040512 @default.
• W3204104051 hasOpenAccess W3204104051 @default.
• W3204104051 hasPrimaryLocation W32041040511 @default.
• W3204104051 hasRelatedWork W1757730638 @default.
• W3204104051 hasRelatedWork W2001420713 @default.
• W3204104051 hasRelatedWork W2012496212 @default.
• W3204104051 hasRelatedWork W2024929539 @default.
• W3204104051 hasRelatedWork W2160926771 @default.
• W3204104051 hasRelatedWork W2381595950 @default.

• next