FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204122381> ?p ?o ?g. }

• W3204122381 abstract "The purpose of the study was to determine the advantages and disadvantages of epi-on corneal cross-linking (CXL) techniques compared with standard epi-off CXL.We searched MEDLINE and EMBASE for randomized controlled trials (RCTs) and non-randomized studies of interventions (NRSIs) and we evaluated the selected papers according to the Cochrane risk of bias tool. We considered, as primary outcomes, average Kmax flattening, changes in uncorrected and corrected distance visual acuity (UDVA and CDVA); as secondary outcomes, we considered changes in pachymetry values and endothelial cell density (ECD). We also investigated adverse events related to the treatments and treatment failure. Meta-analysis was conducted with a fixed or random-effects model using weighted mean difference (MD) with 95% confidence interval (CI) as the effect size.A total of 15 studies were included and among these 15 trials, 9 were RCTs and 6 were NRSIs, but only 4 studies showed no high risk of bias and were included in this meta-analysis. Our analysis revealed significant postoperative differences in CDVA (MD = 0.07; 95% CI 0.04 to 0.10; P < 0.001), and no significative differences in UDVA, Kmax, central corneal thickness (CCT) and ECD (P > 0.05). Epi-on CXL protocol was found to be significantly less prompt to have risks of delay in epithelial healing (P = 0.035) and persistent stromal haze (P = 0.026).Epi-on CXL is as effective as epi-off CXL. Except for a higher significant improvement in CDVA with current epi-on protocols, our meta-analysis demonstrates that epi-on and epi-off CXL have comparable effects on visual, topographic, pachymetric, and endothelial parameters. Epi-on CXL has clinical advantages in terms of comfort and avoidance of complications as it reduces the risk of developing delay in epithelial healing and persistent stromal haze." @default.
• W3204122381 created "2021-10-11" @default.
• W3204122381 creator A5008923268 @default.
• W3204122381 creator A5076990057 @default.
• W3204122381 creator A5091654539 @default.
• W3204122381 date "2021-09-26" @default.
• W3204122381 modified "2023-10-09" @default.
• W3204122381 title "Corneal collagen cross-linking epithelium-on vs. epithelium-off: a systematic review and meta-analysis" @default.
• W3204122381 cites W1565416402 @default.
• W3204122381 cites W1721748233 @default.
• W3204122381 cites W1916037173 @default.
• W3204122381 cites W1967870715 @default.
• W3204122381 cites W1977470900 @default.
• W3204122381 cites W1978332922 @default.
• W3204122381 cites W2031265488 @default.
• W3204122381 cites W2031805454 @default.
• W3204122381 cites W2041939167 @default.
• W3204122381 cites W2067873272 @default.
• W3204122381 cites W2081320515 @default.
• W3204122381 cites W2113430923 @default.
• W3204122381 cites W2119605658 @default.
• W3204122381 cites W2131977403 @default.
• W3204122381 cites W2140648982 @default.
• W3204122381 cites W2162609200 @default.
• W3204122381 cites W2228787964 @default.
• W3204122381 cites W2289402143 @default.
• W3204122381 cites W2313815325 @default.
• W3204122381 cites W2323108829 @default.
• W3204122381 cites W2338224357 @default.
• W3204122381 cites W2340561890 @default.
• W3204122381 cites W2460724299 @default.
• W3204122381 cites W2531269403 @default.
• W3204122381 cites W2531522280 @default.
• W3204122381 cites W2549469138 @default.
• W3204122381 cites W2585032950 @default.
• W3204122381 cites W2589871018 @default.
• W3204122381 cites W2594089469 @default.
• W3204122381 cites W2598701103 @default.
• W3204122381 cites W2755692905 @default.
• W3204122381 cites W2756578555 @default.
• W3204122381 cites W2756714216 @default.
• W3204122381 cites W2767085258 @default.
• W3204122381 cites W2767493461 @default.
• W3204122381 cites W2769509012 @default.
• W3204122381 cites W2791817024 @default.
• W3204122381 cites W2796398002 @default.
• W3204122381 cites W2797997192 @default.
• W3204122381 cites W2805753772 @default.
• W3204122381 cites W2808605148 @default.
• W3204122381 cites W2820756626 @default.
• W3204122381 cites W2887442638 @default.
• W3204122381 cites W2891558130 @default.
• W3204122381 cites W2913608716 @default.
• W3204122381 cites W2915816466 @default.
• W3204122381 cites W2921518465 @default.
• W3204122381 cites W2930086976 @default.
• W3204122381 cites W2940027135 @default.
• W3204122381 cites W2941586266 @default.
• W3204122381 cites W2977908730 @default.
• W3204122381 cites W2978795816 @default.
• W3204122381 cites W2980793156 @default.
• W3204122381 cites W3089688662 @default.
• W3204122381 cites W3176075658 @default.
• W3204122381 cites W4244267183 @default.
• W3204122381 cites W4294215472 @default.
• W3204122381 doi "https://doi.org/10.1186/s40662-021-00256-0" @default.
• W3204122381 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8465763" @default.
• W3204122381 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34565473" @default.
• W3204122381 hasPublicationYear "2021" @default.
• W3204122381 type Work @default.
• W3204122381 sameAs 3204122381 @default.
• W3204122381 citedByCount "7" @default.
• W3204122381 countsByYear W32041223812021 @default.
• W3204122381 countsByYear W32041223812022 @default.
• W3204122381 countsByYear W32041223812023 @default.
• W3204122381 crossrefType "journal-article" @default.
• W3204122381 hasAuthorship W3204122381A5008923268 @default.
• W3204122381 hasAuthorship W3204122381A5076990057 @default.
• W3204122381 hasAuthorship W3204122381A5091654539 @default.
• W3204122381 hasBestOaLocation W32041223811 @default.
• W3204122381 hasConcept C118487528 @default.
• W3204122381 hasConcept C126322002 @default.
• W3204122381 hasConcept C168563851 @default.
• W3204122381 hasConcept C2776731418 @default.
• W3204122381 hasConcept C2778257484 @default.
• W3204122381 hasConcept C2781053140 @default.
• W3204122381 hasConcept C44249647 @default.
• W3204122381 hasConcept C71924100 @default.
• W3204122381 hasConcept C82789193 @default.
• W3204122381 hasConcept C95190672 @default.
• W3204122381 hasConceptScore W3204122381C118487528 @default.
• W3204122381 hasConceptScore W3204122381C126322002 @default.
• W3204122381 hasConceptScore W3204122381C168563851 @default.
• W3204122381 hasConceptScore W3204122381C2776731418 @default.
• W3204122381 hasConceptScore W3204122381C2778257484 @default.
• W3204122381 hasConceptScore W3204122381C2781053140 @default.
• W3204122381 hasConceptScore W3204122381C44249647 @default.
• W3204122381 hasConceptScore W3204122381C71924100 @default.
• W3204122381 hasConceptScore W3204122381C82789193 @default.
• W3204122381 hasConceptScore W3204122381C95190672 @default.

• next