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- W3204132435 abstract "Resin monomers and polymerisation initiators have been shown to be cytotoxic for pulp cells and to disturb odontoblast differentiation. This study aimed to compare the effect of a resin-modified calcium silicate cement (TheraCal LC; TC) and a resin-free calcium silicate cement (ProRoot MTA; PR) on pulpal healing after pulpotomy. Pulpotomy was performed on the maxillary first molars of 8-week-old rats using either PR or TC. After 1, 3, 7, 14 and 28 days, pulpal responses were assessed by micro-computed tomography, haematoxylin-eosin staining and immunostaining against CD68, which is a pan-macrophage marker. The results showed that pulpotomy with TC induced persistent infiltration of inflammatory cells, including CD68-positive macrophages, and delayed the formation of reparative dentin as compared with that with PR, although both materials allowed pulpal healing over the long term. Therefore, resin-modified TC was not as biocompatible nor bioinductive as resin-free PR when applied on the healthy pulp of rat molars." @default.
- W3204132435 created "2021-10-11" @default.
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- W3204132435 date "2021-10-02" @default.
- W3204132435 modified "2023-09-26" @default.
- W3204132435 title "Effect of a resin‐modified calcium silicate cement on inflammatory cell infiltration and reparative dentin formation after pulpotomy in rat molars" @default.
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- W3204132435 doi "https://doi.org/10.1111/aej.12568" @default.
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