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• W3204141054 endingPage "102484" @default.
• W3204141054 startingPage "102484" @default.
• W3204141054 abstract "In recent years, phlorotannins , a class of polyphenols with strong biological properties derived from brown algae and not present in terrestrial organisms , have attracted widespread attention due to their broad application prospects. This review focuses on the extraction methods of phlorotannins and summarizes the structural characterization of phlorotannins with different molecular weight as well as their main biological properties in vitro and in vivo , highlighting future trends and applications of these compounds. There are multiple extraction methods to obtain phlorotannins, being some of the most promising ultrasonic assisted extraction (UAE), microwave assisted extraction (MAE) and enzyme assisted extraction (EAE). However, there is no standard unified extraction method for phlorotannins, and there is still potential for development and optimization of the application of these technologies. In addition, methods involving the combination of multiple extraction techniques should be further explored for phlorotannins' extraction. Moreover, the structural characterization of phlorotannins and its potential bioactivities , such as anti-diabetic, anti-cancer, and anti-inflammatory effects, still need to be further explored. The structural change of phlorotannins with high degree of polymerization may contribute to the increase of its bioactivity. Phlorotannins research trends include more efficient and optimized extraction methods, specific bioactivity of single phlorotannins, relationship between structure and its biological activity, research on drug delivery systems, and development of functional foods and nutraceutical . • The emerging extraction technology of phlorotannins has many potential benefits. • Phlorotannins are only derived from brown algae and have attractive bioactivities. • It is necessary to increase the bioavailability of phlorotannins in vivo . • This review explores possible future application trends of phlorotannins." @default.
• W3204141054 created "2021-10-11" @default.
• W3204141054 creator A5038322152 @default.
• W3204141054 creator A5044937227 @default.
• W3204141054 creator A5045743244 @default.
• W3204141054 creator A5067118541 @default.
• W3204141054 date "2021-12-01" @default.
• W3204141054 modified "2023-10-11" @default.
• W3204141054 title "Phlorotannins: A review of extraction methods, structural characteristics, bioactivities, bioavailability, and future trends" @default.
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