Matches in SemOpenAlex for { <https://semopenalex.org/work/W32041828> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W32041828 abstract "Abstract The critical event in human sex determination is whether the embryonic undifferentiated gonad develops as a testis or an ovary. The formation and maintenance of the undifferentiated gonad requires the concerted action of numerous genes such as SF1/NRA5A1, WT1, LIM1, LHX9, EMX2 , and CBX2 . If the embryo has an XY sex chromosome constitution, then the Y-linked SRY gene initiates a developmental network of genes (SOX9, FGF9, DHH, DMRT1, AMH, DAX1/NROB1, and SF1/NRA5A1) that results in a functional testis. By contrast, in an XX embryo the undifferentiated gonad develops as an ovary under the active developmental regulation of genes such as WNT4, RSPO1, β-catenin, and FOXL2. Perturbation of any of the genes in either the testis or ovary developmental network can result in patients with disorders of sex development (DSD)." @default.
- W32041828 created "2016-06-24" @default.
- W32041828 creator A5066906834 @default.
- W32041828 creator A5086380612 @default.
- W32041828 date "2013-01-01" @default.
- W32041828 modified "2023-09-24" @default.
- W32041828 title "Sex Determination, Human" @default.
- W32041828 cites W1501066624 @default.
- W32041828 cites W1549310626 @default.
- W32041828 cites W1615728431 @default.
- W32041828 cites W1848346234 @default.
- W32041828 cites W1965719589 @default.
- W32041828 cites W1973295687 @default.
- W32041828 cites W1974121679 @default.
- W32041828 cites W1984220883 @default.
- W32041828 cites W2007969716 @default.
- W32041828 cites W2013246689 @default.
- W32041828 cites W2026242783 @default.
- W32041828 cites W2041610749 @default.
- W32041828 cites W2094380636 @default.
- W32041828 cites W2138293493 @default.
- W32041828 cites W2158701974 @default.
- W32041828 cites W2160084983 @default.
- W32041828 doi "https://doi.org/10.1016/b978-0-12-374984-0.01402-9" @default.
- W32041828 hasPublicationYear "2013" @default.
- W32041828 type Work @default.
- W32041828 sameAs 32041828 @default.
- W32041828 citedByCount "0" @default.
- W32041828 crossrefType "book-chapter" @default.
- W32041828 hasAuthorship W32041828A5066906834 @default.
- W32041828 hasAuthorship W32041828A5086380612 @default.
- W32041828 hasConcept C104317684 @default.
- W32041828 hasConcept C134018914 @default.
- W32041828 hasConcept C137487509 @default.
- W32041828 hasConcept C137620995 @default.
- W32041828 hasConcept C145103041 @default.
- W32041828 hasConcept C148102462 @default.
- W32041828 hasConcept C196843134 @default.
- W32041828 hasConcept C2778324911 @default.
- W32041828 hasConcept C2778486617 @default.
- W32041828 hasConcept C2780246931 @default.
- W32041828 hasConcept C2780753755 @default.
- W32041828 hasConcept C2781037291 @default.
- W32041828 hasConcept C2781430442 @default.
- W32041828 hasConcept C2781471917 @default.
- W32041828 hasConcept C54355233 @default.
- W32041828 hasConcept C63405245 @default.
- W32041828 hasConcept C73456138 @default.
- W32041828 hasConcept C86339819 @default.
- W32041828 hasConcept C86803240 @default.
- W32041828 hasConceptScore W32041828C104317684 @default.
- W32041828 hasConceptScore W32041828C134018914 @default.
- W32041828 hasConceptScore W32041828C137487509 @default.
- W32041828 hasConceptScore W32041828C137620995 @default.
- W32041828 hasConceptScore W32041828C145103041 @default.
- W32041828 hasConceptScore W32041828C148102462 @default.
- W32041828 hasConceptScore W32041828C196843134 @default.
- W32041828 hasConceptScore W32041828C2778324911 @default.
- W32041828 hasConceptScore W32041828C2778486617 @default.
- W32041828 hasConceptScore W32041828C2780246931 @default.
- W32041828 hasConceptScore W32041828C2780753755 @default.
- W32041828 hasConceptScore W32041828C2781037291 @default.
- W32041828 hasConceptScore W32041828C2781430442 @default.
- W32041828 hasConceptScore W32041828C2781471917 @default.
- W32041828 hasConceptScore W32041828C54355233 @default.
- W32041828 hasConceptScore W32041828C63405245 @default.
- W32041828 hasConceptScore W32041828C73456138 @default.
- W32041828 hasConceptScore W32041828C86339819 @default.
- W32041828 hasConceptScore W32041828C86803240 @default.
- W32041828 hasLocation W320418281 @default.
- W32041828 hasOpenAccess W32041828 @default.
- W32041828 hasPrimaryLocation W320418281 @default.
- W32041828 hasRelatedWork W1483519527 @default.
- W32041828 hasRelatedWork W1542773988 @default.
- W32041828 hasRelatedWork W1981850122 @default.
- W32041828 hasRelatedWork W2021306295 @default.
- W32041828 hasRelatedWork W2041610749 @default.
- W32041828 hasRelatedWork W2079513459 @default.
- W32041828 hasRelatedWork W2097866537 @default.
- W32041828 hasRelatedWork W2151574415 @default.
- W32041828 hasRelatedWork W2153863438 @default.
- W32041828 hasRelatedWork W2158120612 @default.
- W32041828 hasRelatedWork W2172261345 @default.
- W32041828 hasRelatedWork W2560574425 @default.
- W32041828 hasRelatedWork W2769349083 @default.
- W32041828 hasRelatedWork W2791433191 @default.
- W32041828 hasRelatedWork W2950670163 @default.
- W32041828 hasRelatedWork W3011661945 @default.
- W32041828 hasRelatedWork W3016875637 @default.
- W32041828 hasRelatedWork W3174330431 @default.
- W32041828 hasRelatedWork W80706282 @default.
- W32041828 hasRelatedWork W2772998633 @default.
- W32041828 isParatext "false" @default.
- W32041828 isRetracted "false" @default.
- W32041828 magId "32041828" @default.
- W32041828 workType "book-chapter" @default.