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• W3204204885 endingPage "108217" @default.
• W3204204885 startingPage "108217" @default.
• W3204204885 abstract "Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new type of coronavirus causing coronavirus 2019 (COVID-19) that was first observed in Wuhan, China, in Dec. 2019. An inflammatory immune response targeting children appeared during the pandemic, which was associated with COVID-19 named multisystem inflammatory syndrome in children (MIS-C). Characteristics of MIS-C include the classic inflammation findings, multi-organ dysfunction, and fever as the cardinal feature. Up to now, no specific therapy has been identified for MIS-C. Currently, considerable progress has been obtained in the MIS-C treatment by cell therapy, specially Mesenchymal stem cells (MSCs). Unique properties have been reported for MSCs, such as various resources for purification of cell, high proliferation, self-renewal, non-invasive procedure, tissue regenerator, multidirectional differentiation, and immunosuppression. As indicated by a recent clinical research, MSCs have the ability of reducing disease inflammation and severity in children with MIS-C. In the present review study, the benefits and characteristics of MSCs and exosomes are discussed for treating patients with MIS-C." @default.
• W3204204885 created "2021-10-11" @default.
• W3204204885 creator A5001548051 @default.
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• W3204204885 creator A5021387157 @default.
• W3204204885 creator A5044302912 @default.
• W3204204885 creator A5084670009 @default.
• W3204204885 date "2021-12-01" @default.
• W3204204885 modified "2023-09-27" @default.
• W3204204885 title "Immunotherapy of multisystem inflammatory syndrome in children (MIS-C) following COVID-19 through mesenchymal stem cells" @default.
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