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- W3204222713 abstract "Alzheimer's disease (AD) is the most common cause for dementia worldwide. Until recently, all approved treatments for AD were symptomatic and not disease modifying. On 7 June 2021, the US FDA approved aducanumab, a human IgG1 anti-Aβ monoclonal antibody selective for Aβ aggregates, as the first disease-modifying treatment for AD. Aducanumab is approved in the United States for the treatment of mild cognitive impairment or mild-dementia stage of AD. In this Editorial, we review the trial data for aducanumab in the treatment of AD and the controversies that its approval has generated." @default.
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- W3204222713 date "2021-10-04" @default.
- W3204222713 modified "2023-10-13" @default.
- W3204222713 title "Aducanumab: evidence from clinical trial data and controversies" @default.
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- W3204222713 doi "https://doi.org/10.7573/dic.2021-7-3" @default.
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