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- W3204226049 abstract "Genetic interaction screens have played a critical role in better understanding epistasis and functional relationships among genes. These screens have been conducted at multiple scales, ranging from testing pairwise interactions genome-wide in yeast and bacteria, to more focused screens in multicellular organisms and cultured cells. Here, I describe a strategy that facilitates genetic interaction screens with loss of function alleles in the model organism Caenorhabditis elegans. I also present a simple downstream assay to measure the effects of combinations of mutations on fitness." @default.
- W3204226049 created "2021-10-11" @default.
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- W3204226049 date "2021-01-01" @default.
- W3204226049 modified "2023-09-23" @default.
- W3204226049 title "A Genetic Interaction Screening Approach in C. elegans" @default.
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- W3204226049 doi "https://doi.org/10.1007/978-1-0716-1740-3_4" @default.
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