FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204233272> ?p ?o ?g. }

• W3204233272 abstract "Treatment of bacterial biofilms are difficult and in many cases, expensive. Bacterial biofilms are naturally more resilient to antimicrobial agents than their free-living planktonic counterparts, rendering the community growth harder to control. The present work described the risks of long-term use of an important alternative antimicrobial, silver nanoparticles (NAg), for the first time, on the dominant mode of bacterial growth.NAg could inhibit the formation as well as eradicating an already grown biofilm of Pseudomonas aeruginosa, a pathogen notorious for its resilience to antibiotics. The biofilm-forming bacterium however, evolved a reduced sensitivity to the nanoparticle. Evidence suggests that survival is linked to the development of persister cells within the population. A similar adaptation was also seen upon prolonged exposures to ionic silver (Ag+). The persister population resumed normal growth after subsequent passage in the absence of silver, highlighting the potential risks of recurrent infections with long-term NAg (and Ag+) treatments of biofilm growth. The present study further observed a potential silver/antibiotic cross-resistance, whereby NAg (as well as Ag+) could not eradicate an already growing gentamicin-resistant P. aeruginosa biofilm. The phenomena is thought to result from the hindered biofilm penetration of the silver species. In contrast, both silver formulations inhibited biofilm formation of the resistant strain, presenting a promising avenue for the control of biofilm-forming antibiotic-resistant bacteria.The findings signify the importance to study the nanoparticle adaptation phenomena in the biofilm mode of bacterial growth, which are apparently unique to those already reported with the planktonic growth counterparts. This work sets the foundation for future studies in other globally significant bacterial pathogens when present as biofilms. Scientifically based strategies for management of pathogenic growth is necessary, particularly in this era of increasing antibiotic resistance." @default.
• W3204233272 created "2021-10-11" @default.
• W3204233272 creator A5028967145 @default.
• W3204233272 creator A5036430020 @default.
• W3204233272 creator A5053126836 @default.
• W3204233272 creator A5056097284 @default.
• W3204233272 creator A5060553042 @default.
• W3204233272 creator A5070549538 @default.
• W3204233272 creator A5086457065 @default.
• W3204233272 date "2021-09-27" @default.
• W3204233272 modified "2023-10-10" @default.
• W3204233272 title "Evolution of biofilm-forming pathogenic bacteria in the presence of nanoparticles and antibiotic: adaptation phenomena and cross-resistance" @default.
• W3204233272 cites W1582758854 @default.
• W3204233272 cites W1884184374 @default.
• W3204233272 cites W1924358729 @default.
• W3204233272 cites W1964025651 @default.
• W3204233272 cites W1966811712 @default.
• W3204233272 cites W1967737875 @default.
• W3204233272 cites W1969648681 @default.
• W3204233272 cites W1978899994 @default.
• W3204233272 cites W1992725478 @default.
• W3204233272 cites W1995823206 @default.
• W3204233272 cites W2000812746 @default.
• W3204233272 cites W2012372004 @default.
• W3204233272 cites W2013088619 @default.
• W3204233272 cites W2022792624 @default.
• W3204233272 cites W2024531968 @default.
• W3204233272 cites W2032893012 @default.
• W3204233272 cites W2041819290 @default.
• W3204233272 cites W2045987764 @default.
• W3204233272 cites W2051081823 @default.
• W3204233272 cites W2055767311 @default.
• W3204233272 cites W2058406790 @default.
• W3204233272 cites W2058457363 @default.
• W3204233272 cites W2059592310 @default.
• W3204233272 cites W2061073363 @default.
• W3204233272 cites W2068150197 @default.
• W3204233272 cites W2078735798 @default.
• W3204233272 cites W2079139094 @default.
• W3204233272 cites W2079698171 @default.
• W3204233272 cites W2082169539 @default.
• W3204233272 cites W2082196711 @default.
• W3204233272 cites W2089462559 @default.
• W3204233272 cites W2089854781 @default.
• W3204233272 cites W2091247537 @default.
• W3204233272 cites W2091724263 @default.
• W3204233272 cites W2095990147 @default.
• W3204233272 cites W2097137679 @default.
• W3204233272 cites W2112724802 @default.
• W3204233272 cites W2117064229 @default.
• W3204233272 cites W2117339863 @default.
• W3204233272 cites W2117417490 @default.
• W3204233272 cites W2118904810 @default.
• W3204233272 cites W2119071867 @default.
• W3204233272 cites W2119158206 @default.
• W3204233272 cites W2122836009 @default.
• W3204233272 cites W2123305926 @default.
• W3204233272 cites W2131122830 @default.
• W3204233272 cites W2134604195 @default.
• W3204233272 cites W2136846371 @default.
• W3204233272 cites W2140888876 @default.
• W3204233272 cites W2141984091 @default.
• W3204233272 cites W2147819711 @default.
• W3204233272 cites W2148323109 @default.
• W3204233272 cites W2152761448 @default.
• W3204233272 cites W2156214199 @default.
• W3204233272 cites W2156638962 @default.
• W3204233272 cites W2156788471 @default.
• W3204233272 cites W2157495301 @default.
• W3204233272 cites W2159420263 @default.
• W3204233272 cites W2168879981 @default.
• W3204233272 cites W2171319960 @default.
• W3204233272 cites W2288651843 @default.
• W3204233272 cites W2313740828 @default.
• W3204233272 cites W2341166238 @default.
• W3204233272 cites W2416290591 @default.
• W3204233272 cites W2520683393 @default.
• W3204233272 cites W2586995851 @default.
• W3204233272 cites W2589067428 @default.
• W3204233272 cites W2620952655 @default.
• W3204233272 cites W2744331467 @default.
• W3204233272 cites W2760173088 @default.
• W3204233272 cites W2772995273 @default.
• W3204233272 cites W2777581826 @default.
• W3204233272 cites W2788414941 @default.
• W3204233272 cites W2791193377 @default.
• W3204233272 cites W2884715307 @default.
• W3204233272 cites W2899536636 @default.
• W3204233272 cites W2900578952 @default.
• W3204233272 cites W2903381708 @default.
• W3204233272 cites W2911109735 @default.
• W3204233272 cites W2936193916 @default.
• W3204233272 cites W2940117744 @default.
• W3204233272 cites W2947633849 @default.
• W3204233272 cites W2980364256 @default.
• W3204233272 cites W2997022578 @default.
• W3204233272 cites W2997583280 @default.
• W3204233272 cites W3000670647 @default.
• W3204233272 cites W3012106863 @default.
• W3204233272 cites W3019117478 @default.

• next