Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204265591> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W3204265591 endingPage "7" @default.
- W3204265591 startingPage "1" @default.
- W3204265591 abstract "Hydroxychloroquine is an antimalarial drug used for systemic lupus erythematosus, rheumatoid arthritis, and malaria treatment. However, hydroxychloroquine has several side effects such as ocular toxicity, neurotoxicity, gastrointestinal disorder, and also severe toxicity such as cardiotoxicity. Therefore, therapeutic drug monitoring of high dose or long-term use of hydroxychloroquine is needed. This study aims to obtain an optimum and validated analysis and preparation method for hydroxychloroquine in volumetric absorptive microsampling (VAMS) using the high-performance liquid chromatography–photodiode array detector based on the Food and Drug Administration guidelines (2018). Hydroxychloroquine quantification was performed using HPLC-PDA with Waters Sunfire™ C18 (5 µm; 250 × 4,6 mm) column. Mobile phase consists of acetonitrile-diethylamine 1% (65 : 35, v/v) (isocratic elution) and delivered at a flow rate of 0.8 mL/min throughout the 12 minutes run. Sample in VAMS is extracted by liquid-liquid extraction with ammonia 1% and n-hexane-ethyl acetate (50 : 50 v/v) as a extraction solvent. This method has successfully qualified the Food and Drug Administration (2018) parameters, with 2 ng/mL of LLOQ, range of calibration curve 2–6500 ng/mL, and coefficient of correlation 0.9993–0.9997." @default.
- W3204265591 created "2021-10-11" @default.
- W3204265591 creator A5000899053 @default.
- W3204265591 creator A5049276027 @default.
- W3204265591 creator A5077587897 @default.
- W3204265591 date "2021-09-30" @default.
- W3204265591 modified "2023-09-23" @default.
- W3204265591 title "Development and Validation of the Quantification Method for Hydroxychloroquine in Volumetric Absorptive Microsampling (VAMS) Using High-Performance Liquid Chromatography-Photodiode Array" @default.
- W3204265591 cites W1968662117 @default.
- W3204265591 cites W1984484469 @default.
- W3204265591 cites W1991889011 @default.
- W3204265591 cites W2073594921 @default.
- W3204265591 cites W2188217547 @default.
- W3204265591 cites W2560217826 @default.
- W3204265591 cites W2560774983 @default.
- W3204265591 cites W2599876765 @default.
- W3204265591 cites W2740174481 @default.
- W3204265591 cites W3015514189 @default.
- W3204265591 doi "https://doi.org/10.1155/2021/3500279" @default.
- W3204265591 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8497163" @default.
- W3204265591 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34632395" @default.
- W3204265591 hasPublicationYear "2021" @default.
- W3204265591 type Work @default.
- W3204265591 sameAs 3204265591 @default.
- W3204265591 citedByCount "2" @default.
- W3204265591 countsByYear W32042655912023 @default.
- W3204265591 crossrefType "journal-article" @default.
- W3204265591 hasAuthorship W3204265591A5000899053 @default.
- W3204265591 hasAuthorship W3204265591A5049276027 @default.
- W3204265591 hasAuthorship W3204265591A5077587897 @default.
- W3204265591 hasBestOaLocation W32042655911 @default.
- W3204265591 hasConcept C126322002 @default.
- W3204265591 hasConcept C179998833 @default.
- W3204265591 hasConcept C185592680 @default.
- W3204265591 hasConcept C2779123688 @default.
- W3204265591 hasConcept C2779134260 @default.
- W3204265591 hasConcept C2780035454 @default.
- W3204265591 hasConcept C2780272996 @default.
- W3204265591 hasConcept C3008058167 @default.
- W3204265591 hasConcept C43617362 @default.
- W3204265591 hasConcept C524204448 @default.
- W3204265591 hasConcept C71924100 @default.
- W3204265591 hasConcept C98274493 @default.
- W3204265591 hasConceptScore W3204265591C126322002 @default.
- W3204265591 hasConceptScore W3204265591C179998833 @default.
- W3204265591 hasConceptScore W3204265591C185592680 @default.
- W3204265591 hasConceptScore W3204265591C2779123688 @default.
- W3204265591 hasConceptScore W3204265591C2779134260 @default.
- W3204265591 hasConceptScore W3204265591C2780035454 @default.
- W3204265591 hasConceptScore W3204265591C2780272996 @default.
- W3204265591 hasConceptScore W3204265591C3008058167 @default.
- W3204265591 hasConceptScore W3204265591C43617362 @default.
- W3204265591 hasConceptScore W3204265591C524204448 @default.
- W3204265591 hasConceptScore W3204265591C71924100 @default.
- W3204265591 hasConceptScore W3204265591C98274493 @default.
- W3204265591 hasFunder F4320323819 @default.
- W3204265591 hasLocation W32042655911 @default.
- W3204265591 hasLocation W32042655912 @default.
- W3204265591 hasLocation W32042655913 @default.
- W3204265591 hasOpenAccess W3204265591 @default.
- W3204265591 hasPrimaryLocation W32042655911 @default.
- W3204265591 hasRelatedWork W1991969313 @default.
- W3204265591 hasRelatedWork W2013924808 @default.
- W3204265591 hasRelatedWork W2015025206 @default.
- W3204265591 hasRelatedWork W2051789873 @default.
- W3204265591 hasRelatedWork W2053496326 @default.
- W3204265591 hasRelatedWork W2063706329 @default.
- W3204265591 hasRelatedWork W2078718962 @default.
- W3204265591 hasRelatedWork W2320154790 @default.
- W3204265591 hasRelatedWork W2415882370 @default.
- W3204265591 hasRelatedWork W4299853637 @default.
- W3204265591 hasVolume "2021" @default.
- W3204265591 isParatext "false" @default.
- W3204265591 isRetracted "false" @default.
- W3204265591 magId "3204265591" @default.
- W3204265591 workType "article" @default.