Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204269181> ?p ?o ?g. }
- W3204269181 endingPage "839" @default.
- W3204269181 startingPage "827" @default.
- W3204269181 abstract "Evolutionary processes, including mutation, migration and natural selection, have influenced the prevalence and distribution of various disorders in humans. However, despite a few well-known examples, such as the APOL1 variants - which have undergone positive genetic selection for their ability to confer resistance to Trypanosoma brucei infection but confer a higher risk of chronic kidney disease - little is known about the effects of evolutionary processes that have shaped genetic variation on kidney disease. An understanding of basic concepts in evolutionary genetics provides an opportunity to consider how findings from ancient and archaic genomes could inform our knowledge of evolution and provide insights into how population migration and genetic admixture have shaped the current distribution and landscape of human kidney-associated diseases. Differences in exposures to infectious agents, environmental toxins, dietary components and climate also have the potential to influence the evolutionary genetics of kidneys. Of note, selective pressure on loci associated with kidney disease is often from non-kidney diseases, and thus it is important to understand how the link between genome-wide selected loci and kidney disease occurs in relation to secondary nephropathies." @default.
- W3204269181 created "2021-10-11" @default.
- W3204269181 creator A5028452639 @default.
- W3204269181 creator A5028757918 @default.
- W3204269181 creator A5029478274 @default.
- W3204269181 creator A5070829421 @default.
- W3204269181 creator A5072089289 @default.
- W3204269181 date "2021-09-28" @default.
- W3204269181 modified "2023-10-14" @default.
- W3204269181 title "Evolutionary genetics and acclimatization in nephrology" @default.
- W3204269181 cites W1019814866 @default.
- W3204269181 cites W1516234656 @default.
- W3204269181 cites W1548073962 @default.
- W3204269181 cites W1602867585 @default.
- W3204269181 cites W1855925914 @default.
- W3204269181 cites W1875915783 @default.
- W3204269181 cites W1924380123 @default.
- W3204269181 cites W1935892027 @default.
- W3204269181 cites W1966772525 @default.
- W3204269181 cites W1967279698 @default.
- W3204269181 cites W1975293530 @default.
- W3204269181 cites W1979961466 @default.
- W3204269181 cites W1980453073 @default.
- W3204269181 cites W1985522229 @default.
- W3204269181 cites W1986872715 @default.
- W3204269181 cites W1991607910 @default.
- W3204269181 cites W1993418944 @default.
- W3204269181 cites W1994263888 @default.
- W3204269181 cites W1994272472 @default.
- W3204269181 cites W1998399313 @default.
- W3204269181 cites W2001629081 @default.
- W3204269181 cites W2010550213 @default.
- W3204269181 cites W2011494627 @default.
- W3204269181 cites W2012409823 @default.
- W3204269181 cites W2013599356 @default.
- W3204269181 cites W2014152315 @default.
- W3204269181 cites W2014164870 @default.
- W3204269181 cites W2025026896 @default.
- W3204269181 cites W2028171462 @default.
- W3204269181 cites W2030194230 @default.
- W3204269181 cites W2030788558 @default.
- W3204269181 cites W2033104621 @default.
- W3204269181 cites W2035073281 @default.
- W3204269181 cites W2035245120 @default.
- W3204269181 cites W2037773537 @default.
- W3204269181 cites W2039173438 @default.
- W3204269181 cites W2043247309 @default.
- W3204269181 cites W2043842774 @default.
- W3204269181 cites W2048068440 @default.
- W3204269181 cites W2049842836 @default.
- W3204269181 cites W2051317473 @default.
- W3204269181 cites W2053489483 @default.
- W3204269181 cites W2066615786 @default.
- W3204269181 cites W2066879438 @default.
- W3204269181 cites W2067097191 @default.
- W3204269181 cites W2067911388 @default.
- W3204269181 cites W2072034127 @default.
- W3204269181 cites W2075065809 @default.
- W3204269181 cites W2078473937 @default.
- W3204269181 cites W2083411239 @default.
- W3204269181 cites W2085267883 @default.
- W3204269181 cites W2085343555 @default.
- W3204269181 cites W2089299906 @default.
- W3204269181 cites W2089378839 @default.
- W3204269181 cites W2089555306 @default.
- W3204269181 cites W2092365858 @default.
- W3204269181 cites W2095406357 @default.
- W3204269181 cites W2096584257 @default.
- W3204269181 cites W2097330123 @default.
- W3204269181 cites W2100196653 @default.
- W3204269181 cites W2101161530 @default.
- W3204269181 cites W2102808592 @default.
- W3204269181 cites W2104625700 @default.
- W3204269181 cites W2105362864 @default.
- W3204269181 cites W2115476261 @default.
- W3204269181 cites W2117207378 @default.
- W3204269181 cites W2121965895 @default.
- W3204269181 cites W2124362779 @default.
- W3204269181 cites W2124641083 @default.
- W3204269181 cites W2128633067 @default.
- W3204269181 cites W2128832145 @default.
- W3204269181 cites W2131491353 @default.
- W3204269181 cites W2135040444 @default.
- W3204269181 cites W2137096226 @default.
- W3204269181 cites W2140055542 @default.
- W3204269181 cites W2142059647 @default.
- W3204269181 cites W2142992633 @default.
- W3204269181 cites W2146558696 @default.
- W3204269181 cites W2154394150 @default.
- W3204269181 cites W2156732616 @default.
- W3204269181 cites W2157574389 @default.
- W3204269181 cites W2160180886 @default.
- W3204269181 cites W2161935988 @default.
- W3204269181 cites W2163330679 @default.
- W3204269181 cites W2163722216 @default.
- W3204269181 cites W2165019590 @default.
- W3204269181 cites W2167032249 @default.
- W3204269181 cites W2168162793 @default.