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- W3204270885 abstract "This meta-analysis aims to highlight the impact of cardio-metabolic comorbidities on COVID-19 severity and mortality. A thorough search on major online databases was done for studies describing the clinical outcomes of COVID-19 patients. We used random-effects model to compute pooled estimates for critical or fatal disease. A total of 20,475 patients from 33 eligible studies were included. Maximum risk of development of critical or fatal COVID-19 disease was seen in patients with underlying cardiovascular disease [OR: 3.44, 95% CI: 2.65–4.48] followed by chronic lung disease, hypertension and diabetes mellitus. Of the total cases, 64% had one of the four comorbidities with the most prevalent being hypertension with a pooled prevalence of 27%. Presence of comorbidities like cardiovascular disease, chronic lung disease, hypertension and diabetes mellitus led to a higher risk of development of critical or fatal COVID-19 disease, with maximum risk seen with underlying cardiovascular disease." @default.
- W3204270885 created "2021-10-11" @default.
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- W3204270885 date "2021-11-01" @default.
- W3204270885 modified "2023-09-29" @default.
- W3204270885 title "Impact of metabolic and cardiovascular disease on COVID-19 mortality: A systematic review and meta-analysis" @default.
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- W3204270885 doi "https://doi.org/10.1016/j.dsx.2021.102308" @default.
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