FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204276296> ?p ?o ?g. }

• W3204276296 endingPage "1411" @default.
• W3204276296 startingPage "1411" @default.
• W3204276296 abstract "Pemphigus vulgaris is an autoimmune disease that occurs due to pathogenic autoantibodies that recognize the following epidermal adhesion proteins: desmogleins. Systemic corticosteroids usually decrease the titers of anti-desmoglein autoantibodies and improve patients' conditions. Since modifications of IgG N-glycosylation have been described in some autoimmune diseases, we hypothesized that changes in the pathogenic activity of pemphigus IgG could be related to changes in their N-glycosylation profile. The purpose of this study was to assess, longitudinally, the pathogenicity of pemphigus serum IgG and their N-glycosylation profile during phases of disease activity and clinical remission. The pathogenic activity of serum IgG was measured in vitro on immortalized keratinocytes, by immunofluorescence and dissociation assays, and IgG N-glycans were analyzed by mass spectrometry. We showed (i) a correlation between pemphigus clinical activity and the pathogenicity of serum IgG at baseline and at month 6, while the persistence of the in vitro pathogenic activity of IgG during its evolution, even in patients in clinical remission, seemed to be predictive of relapse; (ii) that modifications of the N-glycan structure were altered the in vitro pathogenicity of patients' autoantibodies; (iii) that the pathogenic properties of pemphigus IgG did not appear to be related to the disparity in IgG N-glycans during the course of pemphigus." @default.
• W3204276296 created "2021-10-11" @default.
• W3204276296 creator A5021199881 @default.
• W3204276296 creator A5024703540 @default.
• W3204276296 creator A5026096828 @default.
• W3204276296 creator A5030014809 @default.
• W3204276296 creator A5036996100 @default.
• W3204276296 creator A5038719486 @default.
• W3204276296 creator A5039998646 @default.
• W3204276296 creator A5042517739 @default.
• W3204276296 creator A5044399363 @default.
• W3204276296 creator A5050985511 @default.
• W3204276296 creator A5058334077 @default.
• W3204276296 creator A5068812467 @default.
• W3204276296 creator A5084492860 @default.
• W3204276296 date "2021-10-08" @default.
• W3204276296 modified "2023-10-17" @default.
• W3204276296 title "Longitudinal Pathogenic Properties and N-Glycosylation Profile of Antibodies from Patients with Pemphigus after Corticosteroid Treatment" @default.
• W3204276296 cites W1550079537 @default.
• W3204276296 cites W1602264889 @default.
• W3204276296 cites W1867392316 @default.
• W3204276296 cites W1907326545 @default.
• W3204276296 cites W1963778872 @default.
• W3204276296 cites W1965399166 @default.
• W3204276296 cites W1972512694 @default.
• W3204276296 cites W1981392048 @default.
• W3204276296 cites W1986197388 @default.
• W3204276296 cites W1999026938 @default.
• W3204276296 cites W2019037591 @default.
• W3204276296 cites W2028627896 @default.
• W3204276296 cites W2035433348 @default.
• W3204276296 cites W2040189845 @default.
• W3204276296 cites W2042115862 @default.
• W3204276296 cites W2043267797 @default.
• W3204276296 cites W2053863608 @default.
• W3204276296 cites W2071919990 @default.
• W3204276296 cites W2100518445 @default.
• W3204276296 cites W2110311209 @default.
• W3204276296 cites W2124940423 @default.
• W3204276296 cites W2136564498 @default.
• W3204276296 cites W2137354517 @default.
• W3204276296 cites W2146961180 @default.
• W3204276296 cites W2158387380 @default.
• W3204276296 cites W2162190636 @default.
• W3204276296 cites W2299193714 @default.
• W3204276296 cites W2328865493 @default.
• W3204276296 cites W2338733954 @default.
• W3204276296 cites W2472943400 @default.
• W3204276296 cites W2549459926 @default.
• W3204276296 cites W2552308644 @default.
• W3204276296 cites W2579989558 @default.
• W3204276296 cites W2602517913 @default.
• W3204276296 cites W2742336213 @default.
• W3204276296 cites W2745553790 @default.
• W3204276296 cites W2756350321 @default.
• W3204276296 cites W2789766907 @default.
• W3204276296 cites W2789884739 @default.
• W3204276296 cites W2808663464 @default.
• W3204276296 cites W2903353754 @default.
• W3204276296 cites W2953110573 @default.
• W3204276296 cites W3018390221 @default.
• W3204276296 cites W3115713292 @default.
• W3204276296 cites W3139385032 @default.
• W3204276296 cites W4206388858 @default.
• W3204276296 cites W4313341528 @default.
• W3204276296 doi "https://doi.org/10.3390/biomedicines9101411" @default.
• W3204276296 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8533488" @default.
• W3204276296 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34680528" @default.
• W3204276296 hasPublicationYear "2021" @default.
• W3204276296 type Work @default.
• W3204276296 sameAs 3204276296 @default.
• W3204276296 citedByCount "1" @default.
• W3204276296 countsByYear W32042762962022 @default.
• W3204276296 crossrefType "journal-article" @default.
• W3204276296 hasAuthorship W3204276296A5021199881 @default.
• W3204276296 hasAuthorship W3204276296A5024703540 @default.
• W3204276296 hasAuthorship W3204276296A5026096828 @default.
• W3204276296 hasAuthorship W3204276296A5030014809 @default.
• W3204276296 hasAuthorship W3204276296A5036996100 @default.
• W3204276296 hasAuthorship W3204276296A5038719486 @default.
• W3204276296 hasAuthorship W3204276296A5039998646 @default.
• W3204276296 hasAuthorship W3204276296A5042517739 @default.
• W3204276296 hasAuthorship W3204276296A5044399363 @default.
• W3204276296 hasAuthorship W3204276296A5050985511 @default.
• W3204276296 hasAuthorship W3204276296A5058334077 @default.
• W3204276296 hasAuthorship W3204276296A5068812467 @default.
• W3204276296 hasAuthorship W3204276296A5084492860 @default.
• W3204276296 hasBestOaLocation W32042762961 @default.
• W3204276296 hasConcept C159654299 @default.
• W3204276296 hasConcept C163764329 @default.
• W3204276296 hasConcept C203014093 @default.
• W3204276296 hasConcept C2777313579 @default.
• W3204276296 hasConcept C2779075594 @default.
• W3204276296 hasConcept C2780898057 @default.
• W3204276296 hasConcept C2781313415 @default.
• W3204276296 hasConcept C2781327288 @default.
• W3204276296 hasConcept C2909223747 @default.
• W3204276296 hasConcept C55493867 @default.

• next