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• W3204277655 abstract "Peptic ulcer is one of the most common gastrointestinal tract disorders worldwide, associated with challenges such as refractory morbidity, bleeding, interference with use of anticoagulants, and potential side effects associated with long-term use of proton pump inhibitors. A peptic ulcer is a defect in gastric or duodenal mucosa extending from muscularis mucosa to deeper layers of the stomach wall. In most cases, ulcers respond to standard treatments. However, in some people, peptic ulcer becomes resistant to conventional treatment or recurs after initially successful therapy. Therefore, new and safe treatments, including the use of stem cells, are highly favored for these patients. Adipose-derived mesenchymal stem cells are readily available in large quantities with minimal invasive intervention, and isolation of adipose-derived mesenchymal stromal stem cells (ASC) produces large amounts of stem cells, which are essential for cell-based and restorative therapies. These cells have high flexibility and can differentiate into several types of cells in vitro. This article will investigate the effects and possible mechanisms and signaling pathways of adipose tissue-derived mesenchymal stem cells in patients with refractory peptic ulcers." @default.
• W3204277655 created "2021-10-11" @default.
• W3204277655 creator A5000909347 @default.
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• W3204277655 date "2021-09-26" @default.
• W3204277655 modified "2023-09-27" @default.
• W3204277655 title "Therapeutic approach of adipose-derived mesenchymal stem cells in refractory peptic ulcer" @default.
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• W3204277655 doi "https://doi.org/10.1186/s13287-021-02584-3" @default.
• W3204277655 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8474857" @default.
• W3204277655 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34565461" @default.
• W3204277655 hasPublicationYear "2021" @default.
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