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• W3204281708 abstract "Aim: This study aims to analyze the effect of dapsone against ischaemia-reperfusion injury on corporal tissue in a model of induced-priapism in rats.&#x0D; Material and Method: A total of 24 rats were randomized into three groups. Group 1 was defined as the control group. Ischaemia-reperfusion injury was evaluated following the priapism model in Group 2. Group 3 had similar procedures to the rats in Group 2. Group 3 additionally had 12.5 mg/kg dapsone administered intraperitoneally 30 minutes after priapism.&#x0D; Results: Biochemical analysis of blood indicated a significant increase in Group 3 in terms of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) activity and total antioxidant status (TAS) values compared with Group 2 (p:0.002, p:0.029 and p:0.009, respectively). The highest values of malondialdehyde (MDA), protein carbonyl (PC) and total oxidant status (TOS) were recorded in Group 2 (p" @default.
• W3204281708 created "2021-10-11" @default.
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• W3204281708 date "2021-09-24" @default.
• W3204281708 modified "2023-10-14" @default.
• W3204281708 title "Dapsone can be a new treatment option for reducing the detrimental effect of priapism" @default.
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• W3204281708 doi "https://doi.org/10.32322/jhsm.963439" @default.
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