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- W3204289966 abstract "The main aim of our study is to nd out efcacy of combined drug Chelerythrine and DADS against chemically induced hepatocarcinoma in male Swiss albino mice.4-6 weeks aged mice were considered for experimentation.Liver cancer was induced by genotoxic carcinogen para- dimethyal-aminoazobenzene along with nongenotoxic promoter carcinogen phenobarbital exposure.During study animals were co-treated with 100mg/kg body weight DADS,5 mg/kg body weight chelerythrine individually or in combination for 120 days. Morphological and histopathological tissue analysis were performed for the conrmation of our objectives.Lots of nodule formation were observed after carcinogen exposure, that causes morphological changes in liver tissue.Histological analysis of the said tissue also demonstrated the reservation of tissue structures in the treated groups, most signicantly in the combined treatment.So in concluding remark we can say combined impact of drugs protect the liver tissue structure from harmful carcinogenic exposure in male Swiss albino mice" @default.
- W3204289966 created "2021-10-11" @default.
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- W3204289966 date "2021-06-15" @default.
- W3204289966 modified "2023-09-25" @default.
- W3204289966 title "AMELIORATING EFFECT OF CHELERYTHRINE AND DADS AGAINST CHEMICALLY INDUCED HEPATOCARCINOMA IN MALE SWISS ALBINO MICE." @default.
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- W3204289966 doi "https://doi.org/10.36106/gjra/5109668" @default.
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