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- W3204336506 abstract "In the present study, phenolic compounds were extracted from Meghalayan cherry (Prunus nepalensis) pomace by conventional solvent extraction (CSE) and microwave-assisted extraction (MAE) methods, and their bio-accessibility, phenolic compound profile, and antioxidant activity were studied after in vitro gastrointestinal digestion. Response surface methodology was applied to optimize the extraction conditions, i.e., solvent concentration (40–80%), solvent-solid ratio (10–30 mL/g), extraction time (90–240 s), and microwave power (300–600W). The extract obtained at optimized MAE conditions had a high yield (44.15 ± 2.06%), total phenolic content (TPC) (155.27 ± 2.76 mgGAE/g), DPPH (92.23 ± 2.19%), and FRAP (0.64 ± 0.01 mgAAE/g) activity. These results indicated high antioxidant activity in MAE compared to CSE with reduced time and energy consumption. The HPLC profile analysis of in vitro digestion of the extracts indicated a higher bio-accessibility of phenolic acids compared to flavonoids. Of the total 11 compounds identified in MAE, hydroxybenzoic acid (128.48%), chlorogenic acid (75.18%), and rutin (50.37%) were the most bio-accessible phenolics and flavonoids in the pomace extract. Even after in vitro digestion, the phenolic compounds of MAE presented adequate antioxidant activity. These findings indicated that the health-promoting properties of pomace phenolics could be modified after gastrointestinal digestion." @default.
- W3204336506 created "2021-10-11" @default.
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- W3204336506 date "2022-01-01" @default.
- W3204336506 modified "2023-09-30" @default.
- W3204336506 title "Effect of extraction methods and simulated in vitro gastrointestinal digestion on phenolic compound profile, bio-accessibility, and antioxidant activity of Meghalayan cherry (Prunus nepalensis) pomace extracts" @default.
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- W3204336506 doi "https://doi.org/10.1016/j.lwt.2021.112570" @default.
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