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• W3204361702 startingPage "41" @default.
• W3204361702 abstract "Protozoa of the genus Leishmania are intracellular parasites that cause human leishmaniasis, a disease spread mostly in the tropics and subtropics. Leishmania cycle between the midgut of female sand flies and phagolysosome of mammalian macrophages. During their life cycle they constantly encounter changing nutritional environments. To monitor the external concentration of essential nutrients, the invading parasites employ sensors that report on the availability of these nutrients; but to-date only a few sensing pathways have been identified in Leishmania. This review focuses on the Arginine Deprivation Response, which both extracellular and intracellular Leishmania utilize to monitor environmental arginine and adjust their arginine transporter (AAP3) levels accordingly." @default.
• W3204361702 created "2021-10-11" @default.
• W3204361702 creator A5043469393 @default.
• W3204361702 creator A5048175967 @default.
• W3204361702 date "2021-09-27" @default.
• W3204361702 modified "2023-09-26" @default.
• W3204361702 title "Arginine sensing in intracellular parasitism of Leishmania." @default.
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• W3204361702 doi "https://doi.org/10.1016/j.mib.2021.09.003" @default.
• W3204361702 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34592588" @default.
• W3204361702 hasPublicationYear "2021" @default.
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