FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204366335> ?p ?o ?g. }

• W3204366335 endingPage "114695" @default.
• W3204366335 startingPage "114695" @default.
• W3204366335 abstract "Thymus persicus (Roniger ex Reach F.) is an Iranian endemic medicinal plant of which essential oil and various products have numerous food and pharmaceutical applications (headache and fever treatments).This modern research included Swiss mice to investigate the anti-nociceptive and anti-neuropathic effects of Thymus persicus aerial parts essential oil (TPEO).To determine TPEO's anti-nociceptive function in the formalin-induced paw licking (FML), researchers looked at the L-arginine/NO/cGMP/KATP channel signaling pathway as well as multiple receptors as with serotonin, morphine, dopamine, and peroxisome proliferator-activated receptors. The CVC or cervical spinal cord contusion exemplar has also been used to induce neuropathic pain.TPEO (50, 100, and 150 mg/kg) relative to control mice in the phase-II of FML provided strong antinociception (p < 0.05, p < 0.01, p < 0.001, respectively). Furthermore, methylene blue, glibenclamide, Nω-nitro-L-arginine methyl ester, naloxonazine, nor-binaltorphimine, prazosin, yohimbine, and ondansetron pre-treating restored the TPEO anti-nociceptive activity in the FML (phase-II) exemplar (p < 0.05). In phase-II of the FML exemplar, carvacrol (one of the active components of TPEO) also greatly reduced pain (p < 0.001). Likewise, in CVC mice, TPEO altered mechanical allodynia and hyperalgesia.It was attained magnificently that TPEO could exerts antinociceptive effects through the involvement of L-arginine/NO/cGMP/KATP signaling pathway, adrenergic, opioid, and serotonin receptors. Moreover, it is demonstrate that anti-neuropathic activity of TPEO may be mediated by inflammatory function." @default.
• W3204366335 created "2021-10-11" @default.
• W3204366335 creator A5005820630 @default.
• W3204366335 creator A5037483918 @default.
• W3204366335 creator A5046131348 @default.
• W3204366335 creator A5089231002 @default.
• W3204366335 date "2022-01-01" @default.
• W3204366335 modified "2023-10-18" @default.
• W3204366335 title "Thymus persicus (Ronniger ex Rech. f.) Jalas alleviates nociceptive and neuropathic pain behavior in mice: Multiple mechanisms of action" @default.
• W3204366335 cites W1565356333 @default.
• W3204366335 cites W1963558935 @default.
• W3204366335 cites W1969028795 @default.
• W3204366335 cites W1970918436 @default.
• W3204366335 cites W1993364218 @default.
• W3204366335 cites W1999864181 @default.
• W3204366335 cites W2001250659 @default.
• W3204366335 cites W2001933690 @default.
• W3204366335 cites W2029969214 @default.
• W3204366335 cites W2057363797 @default.
• W3204366335 cites W2073050255 @default.
• W3204366335 cites W2074119449 @default.
• W3204366335 cites W2078743143 @default.
• W3204366335 cites W2079909417 @default.
• W3204366335 cites W2081820911 @default.
• W3204366335 cites W2104818454 @default.
• W3204366335 cites W2109781640 @default.
• W3204366335 cites W2128412489 @default.
• W3204366335 cites W2317058085 @default.
• W3204366335 cites W2339802165 @default.
• W3204366335 cites W2528635319 @default.
• W3204366335 cites W2604958442 @default.
• W3204366335 cites W2912264638 @default.
• W3204366335 cites W2942017155 @default.
• W3204366335 cites W2983136519 @default.
• W3204366335 cites W3006686178 @default.
• W3204366335 cites W3008029073 @default.
• W3204366335 cites W3011280770 @default.
• W3204366335 cites W3013429985 @default.
• W3204366335 cites W3035847320 @default.
• W3204366335 cites W3045854155 @default.
• W3204366335 cites W3046104218 @default.
• W3204366335 cites W3092719422 @default.
• W3204366335 cites W3094563918 @default.
• W3204366335 cites W3100514562 @default.
• W3204366335 cites W3107267668 @default.
• W3204366335 cites W3114045972 @default.
• W3204366335 cites W3134297589 @default.
• W3204366335 doi "https://doi.org/10.1016/j.jep.2021.114695" @default.
• W3204366335 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34597655" @default.
• W3204366335 hasPublicationYear "2022" @default.
• W3204366335 type Work @default.
• W3204366335 sameAs 3204366335 @default.
• W3204366335 citedByCount "4" @default.
• W3204366335 countsByYear W32043663352022 @default.
• W3204366335 crossrefType "journal-article" @default.
• W3204366335 hasAuthorship W3204366335A5005820630 @default.
• W3204366335 hasAuthorship W3204366335A5037483918 @default.
• W3204366335 hasAuthorship W3204366335A5046131348 @default.
• W3204366335 hasAuthorship W3204366335A5089231002 @default.
• W3204366335 hasConcept C126322002 @default.
• W3204366335 hasConcept C15490471 @default.
• W3204366335 hasConcept C170493617 @default.
• W3204366335 hasConcept C185592680 @default.
• W3204366335 hasConcept C2776885963 @default.
• W3204366335 hasConcept C2777107010 @default.
• W3204366335 hasConcept C2777676773 @default.
• W3204366335 hasConcept C2777883359 @default.
• W3204366335 hasConcept C2779245659 @default.
• W3204366335 hasConcept C2780648677 @default.
• W3204366335 hasConcept C2780723003 @default.
• W3204366335 hasConcept C2781063702 @default.
• W3204366335 hasConcept C42219234 @default.
• W3204366335 hasConcept C71924100 @default.
• W3204366335 hasConcept C98274493 @default.
• W3204366335 hasConceptScore W3204366335C126322002 @default.
• W3204366335 hasConceptScore W3204366335C15490471 @default.
• W3204366335 hasConceptScore W3204366335C170493617 @default.
• W3204366335 hasConceptScore W3204366335C185592680 @default.
• W3204366335 hasConceptScore W3204366335C2776885963 @default.
• W3204366335 hasConceptScore W3204366335C2777107010 @default.
• W3204366335 hasConceptScore W3204366335C2777676773 @default.
• W3204366335 hasConceptScore W3204366335C2777883359 @default.
• W3204366335 hasConceptScore W3204366335C2779245659 @default.
• W3204366335 hasConceptScore W3204366335C2780648677 @default.
• W3204366335 hasConceptScore W3204366335C2780723003 @default.
• W3204366335 hasConceptScore W3204366335C2781063702 @default.
• W3204366335 hasConceptScore W3204366335C42219234 @default.
• W3204366335 hasConceptScore W3204366335C71924100 @default.
• W3204366335 hasConceptScore W3204366335C98274493 @default.
• W3204366335 hasLocation W32043663351 @default.
• W3204366335 hasLocation W32043663352 @default.
• W3204366335 hasOpenAccess W3204366335 @default.
• W3204366335 hasPrimaryLocation W32043663351 @default.
• W3204366335 hasRelatedWork W1487650343 @default.
• W3204366335 hasRelatedWork W1923483939 @default.
• W3204366335 hasRelatedWork W1963649833 @default.
• W3204366335 hasRelatedWork W1999401933 @default.
• W3204366335 hasRelatedWork W2019826876 @default.

• next