FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204395571> ?p ?o ?g. }

• W3204395571 endingPage "631" @default.
• W3204395571 startingPage "624" @default.
• W3204395571 abstract "Patients with breast cancer are increasingly being offered breast conserving surgery (BCS) following neoadjuvant chemotherapy (NACT). We aimed to conduct a systematic review to assess the advantage of tumor marking in patients undergoing BCS after NACT. After registering the protocol for a systematic review with PROSPERO, a systematic search was conducted through September 30, 2020, for all studies involving patients undergoing BCS post NACT after tumor marking. Margin status on final histology was the primary outcome. Oxford Centre for Evidence Based Medicine (OCEBM) levels were used to assess internal validity. A total of 636 records from Medline/PubMed, 1381 from Embase, and 1422 from Cochrane library were extracted. After screening, 15 articles (1520 patients) were included for data synthesis. For marking, 6 studies used metallic markers and 5 used 125I-radioactive seeds (RSL) followed by skin tattoo and radio-guided occult lesion localization using 99mTc (ROLL) in one study each. Most studies used a single marker at the center except for two (143 patients), who practiced the bracketing technique. Incidence of unsatisfactory margins (positive/close) ranged from 5 to 23.5%. After excluding patients with complete pathological response, the “adjusted unsatisfactory margin” rate was found to be 19.3% (10.4–33%). Overall 20.6 recurrences (locoregional/distant) were reported per 1000 patient-years follow-up. Overall survival (OS) was only reported by one study as 96.6% and 84.7% in patients with and without marker placement (p = .01). Re-excision and secondary mastectomy rates (reported by nine studies) were 7.3% and 5.7% respectively. There is limited evidence that tumor marking before neoadjuvant chemotherapy improves the rate of unsatisfactory margins or survival outcomes in a patient undergoing BCS after NACT." @default.
• W3204395571 created "2021-10-11" @default.
• W3204395571 creator A5018848736 @default.
• W3204395571 creator A5018990933 @default.
• W3204395571 creator A5039632376 @default.
• W3204395571 creator A5042537926 @default.
• W3204395571 creator A5070231406 @default.
• W3204395571 date "2021-08-03" @default.
• W3204395571 modified "2023-09-24" @default.
• W3204395571 title "Does Tumor Marking Before Neoadjuvant Chemotherapy Helps Achieve Better Outcomes in Patients Undergoing Breast Conservative Surgery? A Systematic Review " @default.
• W3204395571 cites W1858287666 @default.
• W3204395571 cites W1896776407 @default.
• W3204395571 cites W1901051485 @default.
• W3204395571 cites W1925213512 @default.
• W3204395571 cites W1956784352 @default.
• W3204395571 cites W1971575660 @default.
• W3204395571 cites W1986243838 @default.
• W3204395571 cites W2005903771 @default.
• W3204395571 cites W2006955737 @default.
• W3204395571 cites W2013686142 @default.
• W3204395571 cites W2016051726 @default.
• W3204395571 cites W2018179599 @default.
• W3204395571 cites W2021825887 @default.
• W3204395571 cites W2026995654 @default.
• W3204395571 cites W2047927113 @default.
• W3204395571 cites W2082799170 @default.
• W3204395571 cites W2083072395 @default.
• W3204395571 cites W2097897450 @default.
• W3204395571 cites W2107313771 @default.
• W3204395571 cites W2147672773 @default.
• W3204395571 cites W2156098321 @default.
• W3204395571 cites W2171958606 @default.
• W3204395571 cites W2345505536 @default.
• W3204395571 cites W2755620810 @default.
• W3204395571 cites W2775275721 @default.
• W3204395571 cites W2921006830 @default.
• W3204395571 cites W2991792334 @default.
• W3204395571 cites W2995069555 @default.
• W3204395571 cites W3084532888 @default.
• W3204395571 cites W4253600741 @default.
• W3204395571 doi "https://doi.org/10.1007/s13193-021-01393-7" @default.
• W3204395571 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8490601" @default.
• W3204395571 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34658593" @default.
• W3204395571 hasPublicationYear "2021" @default.
• W3204395571 type Work @default.
• W3204395571 sameAs 3204395571 @default.
• W3204395571 citedByCount "0" @default.
• W3204395571 crossrefType "journal-article" @default.
• W3204395571 hasAuthorship W3204395571A5018848736 @default.
• W3204395571 hasAuthorship W3204395571A5018990933 @default.
• W3204395571 hasAuthorship W3204395571A5039632376 @default.
• W3204395571 hasAuthorship W3204395571A5042537926 @default.
• W3204395571 hasAuthorship W3204395571A5070231406 @default.
• W3204395571 hasBestOaLocation W32043955712 @default.
• W3204395571 hasConcept C121608353 @default.
• W3204395571 hasConcept C126322002 @default.
• W3204395571 hasConcept C141071460 @default.
• W3204395571 hasConcept C142724271 @default.
• W3204395571 hasConcept C143998085 @default.
• W3204395571 hasConcept C17744445 @default.
• W3204395571 hasConcept C189708586 @default.
• W3204395571 hasConcept C199539241 @default.
• W3204395571 hasConcept C204787440 @default.
• W3204395571 hasConcept C2776478404 @default.
• W3204395571 hasConcept C2776694085 @default.
• W3204395571 hasConcept C2777704003 @default.
• W3204395571 hasConcept C2777757722 @default.
• W3204395571 hasConcept C2778292576 @default.
• W3204395571 hasConcept C2779473830 @default.
• W3204395571 hasConcept C2780140570 @default.
• W3204395571 hasConcept C2781467025 @default.
• W3204395571 hasConcept C520017518 @default.
• W3204395571 hasConcept C530470458 @default.
• W3204395571 hasConcept C71924100 @default.
• W3204395571 hasConcept C95190672 @default.
• W3204395571 hasConceptScore W3204395571C121608353 @default.
• W3204395571 hasConceptScore W3204395571C126322002 @default.
• W3204395571 hasConceptScore W3204395571C141071460 @default.
• W3204395571 hasConceptScore W3204395571C142724271 @default.
• W3204395571 hasConceptScore W3204395571C143998085 @default.
• W3204395571 hasConceptScore W3204395571C17744445 @default.
• W3204395571 hasConceptScore W3204395571C189708586 @default.
• W3204395571 hasConceptScore W3204395571C199539241 @default.
• W3204395571 hasConceptScore W3204395571C204787440 @default.
• W3204395571 hasConceptScore W3204395571C2776478404 @default.
• W3204395571 hasConceptScore W3204395571C2776694085 @default.
• W3204395571 hasConceptScore W3204395571C2777704003 @default.
• W3204395571 hasConceptScore W3204395571C2777757722 @default.
• W3204395571 hasConceptScore W3204395571C2778292576 @default.
• W3204395571 hasConceptScore W3204395571C2779473830 @default.
• W3204395571 hasConceptScore W3204395571C2780140570 @default.
• W3204395571 hasConceptScore W3204395571C2781467025 @default.
• W3204395571 hasConceptScore W3204395571C520017518 @default.
• W3204395571 hasConceptScore W3204395571C530470458 @default.
• W3204395571 hasConceptScore W3204395571C71924100 @default.
• W3204395571 hasConceptScore W3204395571C95190672 @default.
• W3204395571 hasIssue "3" @default.
• W3204395571 hasLocation W32043955711 @default.

• next