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- W3204396044 abstract "Ischemia-reperfusion injury is a rare but serious complication encountered after spinal decompression surgery. This is only the 11th case reported in the literature. There is no current mainstay of treatment; however, several therapies have been studied. This case presents a patient with myelomalacia who underwent posterior laminectomy and developed diffuse cord edema with postoperative quadriplegia. Ischemia-reperfusion injury is believed to be mediated by oxidative and nitrosative stress leading to protein degradation and lipid peroxidation. It is characterized by myelomalacia in a chronically ischemic spinal cord and hyperintensity on T2-weighted MRI after decompression. Treatment has involved steroids and rehabilitation, and outcomes have ranged from minor improvement to full recovery. Novel treatment options have shown promise in animal models." @default.
- W3204396044 created "2021-10-11" @default.
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- W3204396044 date "2021-09-26" @default.
- W3204396044 modified "2023-10-07" @default.
- W3204396044 title "Ischemia-Reperfusion Injury After Posterior Cervical Laminectomy" @default.
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- W3204396044 doi "https://doi.org/10.7759/cureus.18298" @default.
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