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- W3204397395 abstract "Immune thrombocytopenia (ITP) is a rare autoimmune disorder, caused by immunologic destruction and insufficient compensatory production of platelets. The management and treatment of ITP depends on estimated risks including platelet count, symptomatic severity, and duration of disease.1 One of the more recent second-line therapies for enhancing platelet production in patients with ITP is the use of thrombopoietin receptor agonist (TPO-RA), such as eltrombopag.1 However, some randomized controlled trials have reported severe adverse effects of arterial and venous thromboembolic events from using TPO-RA, but the pathophysiology and risk factors have not been well elucidated.2 Regarding thromboembolic events, a clinical dilemma arises when a patient with acute coronary syndrome (ACS) presents with ITP from TPO-RA treatment because a balance must be maintained between bleeding events and thromboembolism. Here, we report a case of recurrent fatal coronary thrombosis in a middle-aged woman with chronic ITP on eltrombopag." @default.
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- W3204397395 date "2021-09-01" @default.
- W3204397395 modified "2023-09-24" @default.
- W3204397395 title "Refractory Coronary Stent Thrombosis in a Patient with Chronic Immune Thrombocytopenia on Eltrombopag." @default.
- W3204397395 doi "https://doi.org/10.6515/acs.202109_37(5).20210518a" @default.
- W3204397395 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8414068" @default.
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