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- W3204407667 abstract "Introduction: Galectin-3 is a structurally unique member of a family of multifunctional beta-galactoside-binding lectins that are important in the regulation of inflammation, immunity, and cancer. Goals. A study has been carried out in 36 apparently healthy patients without known heart disease and in 52 patients who mainly suffered from heart failure (HF). Material and methods: Patient samples have been processed with a chemiluminescent immunoassay (CMIA) (Abbott Diagnostics) on an Architect. The assay is based on two monoclonal antibodies (87B5 and M3 / 38) specific for galectin-3. The increase in galectin-3 has been associated with fibroblast proliferation, a key component in the establishment of cardiac restructuring. The determination of BNP and cardiac troponin I was carried out on a Univel Dxi600 autoanalyzer (Beckman Coulter). Results: The mean levels of galectin-3 obtained in the group of healthy patients was 25.3±17.3 ng / ml, while the mean levels of the 52 patients with…" @default.
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- W3204407667 date "2005-04-08" @default.
- W3204407667 modified "2023-10-12" @default.
- W3204407667 title "GALECTIN 3: NEW MARKER FOR MONITORING CLINICAL HEART FAILURE" @default.
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