Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204432666> ?p ?o ?g. }
- W3204432666 abstract "Chemosensory cues detected in the nose need to be integrated with the hormonal status to trigger appropriate behaviors, but the neural circuits linking the olfactory and the endocrine system are insufficiently understood. Here, we characterize olfactory sensory neurons in the murine nose that respond to the pituitary hormone prolactin. Deletion of prolactin receptor in these cells results in impaired detection of social odors and blunts male preference in females. The prolactin-responsive olfactory sensory neurons exhibit a distinctive projection pattern to the brain that is similar across different individuals and express a limited subset of chemosensory receptors. Prolactin modulates the responses within these neurons to discrete chemosensory cues contained in male urine, providing a mechanism by which the hormonal status can be directly linked with distinct olfactory cues to generate appropriate behavioral responses." @default.
- W3204432666 created "2021-10-11" @default.
- W3204432666 creator A5002035077 @default.
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- W3204432666 creator A5083718409 @default.
- W3204432666 date "2021-10-08" @default.
- W3204432666 modified "2023-10-17" @default.
- W3204432666 title "Prolactin-sensitive olfactory sensory neurons regulate male preference in female mice by modulating responses to chemosensory cues" @default.
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