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- W3204433162 abstract "We present an unprecedented atroposelective [8+2] cycloaddition reaction between pyridinium/isoquinolinium ylides and ynals. It is worth noting that this protocol represents a new example of the organocatalyzed atropoenantioselective higher-order cycloaddition reaction, providing various axial chiral 3-arylindolizines in good yields and high enantioselectivities. In addition, the obtained axially chiral 3-aryldolizines also provide many opportunities for structural transformations and potential drug discovery." @default.
- W3204433162 created "2021-10-11" @default.
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- W3204433162 date "2021-09-30" @default.
- W3204433162 modified "2023-10-02" @default.
- W3204433162 title "Organocatalytic Higher-Order [8+2] Cycloaddition for the Assembly of Atropoenantiomeric 3-Arylindolizines" @default.
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- W3204433162 doi "https://doi.org/10.1021/acs.orglett.1c03220" @default.
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