FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204539462> ?p ?o ?g. }

• W3204539462 endingPage "2024" @default.
• W3204539462 startingPage "2024" @default.
• W3204539462 abstract "Laryngeal papilloma (LP), which is associated with infection by human papillomavirus (HPV)-6 or -11, displays aggressive growth. The precise molecular mechanism underlying the tumorigenesis of LP has yet to be uncovered. Building on our earlier research into HPV-6, in this study, the viral gene expression of HPV-11 was investigated by quantitative PCR and DNA/RNA in situ hybridization. Additionally, newly developed antibodies against the E4 protein of HPV-6 and HPV-11 were evaluated by immunohistochemistry. The average viral load of HPV-11 in LP was 1.95 ± 0.66 × 105 copies/ng DNA, and 88% of HPV mRNA expression was found to be E4, E5a, and E5b mRNAs. According to RNA in situ hybridization, E4 and E5b mRNAs were expressed from the middle to upper part of the epithelium. E4 immunohistochemistry revealed a wide positive reaction in the upper cell layer in line with E4 mRNA expression. Other head and neck lesions with HPV-11 infection also showed a positive reaction in E4 immunohistochemistry. The distribution pattern of HPV DNA, viral mRNA, and E4 protein in LP with HPV-11 infection was quite similar to that of HPV-6. Therefore, it might be possible to apply these E4-specific antibodies in other functional studies as well as clinical applications, including targeted molecular therapies in patients with HPV-6 and HPV-11 infection." @default.
• W3204539462 created "2021-10-11" @default.
• W3204539462 creator A5004946364 @default.
• W3204539462 creator A5013786499 @default.
• W3204539462 creator A5014672369 @default.
• W3204539462 creator A5016668959 @default.
• W3204539462 creator A5017133281 @default.
• W3204539462 creator A5029426503 @default.
• W3204539462 creator A5046619240 @default.
• W3204539462 creator A5052475825 @default.
• W3204539462 creator A5068477832 @default.
• W3204539462 creator A5074942490 @default.
• W3204539462 creator A5075889719 @default.
• W3204539462 creator A5078655407 @default.
• W3204539462 creator A5080299485 @default.
• W3204539462 creator A5082449956 @default.
• W3204539462 creator A5090666761 @default.
• W3204539462 date "2021-10-07" @default.
• W3204539462 modified "2023-09-26" @default.
• W3204539462 title "Development of Antibodies against HPV-6 and HPV-11 for the Study of Laryngeal Papilloma" @default.
• W3204539462 cites W1492665086 @default.
• W3204539462 cites W1967757856 @default.
• W3204539462 cites W1976978741 @default.
• W3204539462 cites W1977574486 @default.
• W3204539462 cites W1999245877 @default.
• W3204539462 cites W2007733233 @default.
• W3204539462 cites W2017473511 @default.
• W3204539462 cites W2032310661 @default.
• W3204539462 cites W2042617633 @default.
• W3204539462 cites W2063278125 @default.
• W3204539462 cites W2068965703 @default.
• W3204539462 cites W2108621249 @default.
• W3204539462 cites W2109892705 @default.
• W3204539462 cites W2138731914 @default.
• W3204539462 cites W2143493651 @default.
• W3204539462 cites W2514536322 @default.
• W3204539462 cites W2565448904 @default.
• W3204539462 cites W2603870775 @default.
• W3204539462 cites W2742825478 @default.
• W3204539462 cites W2744412017 @default.
• W3204539462 cites W2805881517 @default.
• W3204539462 cites W2896389131 @default.
• W3204539462 cites W2907680242 @default.
• W3204539462 cites W2941838466 @default.
• W3204539462 cites W2995052149 @default.
• W3204539462 cites W3133772691 @default.
• W3204539462 cites W3172807922 @default.
• W3204539462 cites W3188499254 @default.
• W3204539462 cites W3425866 @default.
• W3204539462 doi "https://doi.org/10.3390/v13102024" @default.
• W3204539462 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8539961" @default.
• W3204539462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34696453" @default.
• W3204539462 hasPublicationYear "2021" @default.
• W3204539462 type Work @default.
• W3204539462 sameAs 3204539462 @default.
• W3204539462 citedByCount "4" @default.
• W3204539462 countsByYear W32045394622022 @default.
• W3204539462 countsByYear W32045394622023 @default.
• W3204539462 crossrefType "journal-article" @default.
• W3204539462 hasAuthorship W3204539462A5004946364 @default.
• W3204539462 hasAuthorship W3204539462A5013786499 @default.
• W3204539462 hasAuthorship W3204539462A5014672369 @default.
• W3204539462 hasAuthorship W3204539462A5016668959 @default.
• W3204539462 hasAuthorship W3204539462A5017133281 @default.
• W3204539462 hasAuthorship W3204539462A5029426503 @default.
• W3204539462 hasAuthorship W3204539462A5046619240 @default.
• W3204539462 hasAuthorship W3204539462A5052475825 @default.
• W3204539462 hasAuthorship W3204539462A5068477832 @default.
• W3204539462 hasAuthorship W3204539462A5074942490 @default.
• W3204539462 hasAuthorship W3204539462A5075889719 @default.
• W3204539462 hasAuthorship W3204539462A5078655407 @default.
• W3204539462 hasAuthorship W3204539462A5080299485 @default.
• W3204539462 hasAuthorship W3204539462A5082449956 @default.
• W3204539462 hasAuthorship W3204539462A5090666761 @default.
• W3204539462 hasBestOaLocation W32045394621 @default.
• W3204539462 hasConcept C104317684 @default.
• W3204539462 hasConcept C105580179 @default.
• W3204539462 hasConcept C121608353 @default.
• W3204539462 hasConcept C142724271 @default.
• W3204539462 hasConcept C153911025 @default.
• W3204539462 hasConcept C159047783 @default.
• W3204539462 hasConcept C159654299 @default.
• W3204539462 hasConcept C203014093 @default.
• W3204539462 hasConcept C204232928 @default.
• W3204539462 hasConcept C2776350393 @default.
• W3204539462 hasConcept C2778220009 @default.
• W3204539462 hasConcept C2778580637 @default.
• W3204539462 hasConcept C502942594 @default.
• W3204539462 hasConcept C529295009 @default.
• W3204539462 hasConcept C54355233 @default.
• W3204539462 hasConcept C555283112 @default.
• W3204539462 hasConcept C67705224 @default.
• W3204539462 hasConcept C71924100 @default.
• W3204539462 hasConcept C81439078 @default.
• W3204539462 hasConcept C86803240 @default.
• W3204539462 hasConceptScore W3204539462C104317684 @default.
• W3204539462 hasConceptScore W3204539462C105580179 @default.
• W3204539462 hasConceptScore W3204539462C121608353 @default.

• next