Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204548832> ?p ?o ?g. }
- W3204548832 endingPage "1456" @default.
- W3204548832 startingPage "1456" @default.
- W3204548832 abstract "Non-steroidal anti-inflammatory drugs (NSAIDs) are Food and Drug Administration (FDA) approved antipyretic, anti-inflammatory, and analgesic drugs to mitigate pain, however it is associated with gastrointestinal injury and cardiovascular disease in some individuals. Metabolomics has the potential to understand the interaction of host and the drugs, such as NSAIDs administration. This discipline has been used by many researchers to understand the serious side effects of NSAIDs. We highlighted (1) the potential of metabolomics in understanding the pathogenesis of adverse events due to NSAIDs administration; (2) choice of metabolomics techniques, bio sample handling; (3) review of metabolomics studies in the front of NSAIDs in different biofluids and tissues; (4) pathway analysis of the data presented in the published literature. In our analysis we find tricarboxylic acid cycle (TCA), glycine serine and threonine metabolism, alanine, aspartate, and glutamate metabolism, and fatty acid metabolism to be altered by the NSAIDs like ibuprofen, indomethacin, naproxen, aspirin, and celecoxib. In conclusion, metabolomics allows the use of biological samples to identify useful pathways involved in disease progression, and subsequently inform a greater understanding of the disease pathogenesis. A further in-depth investigation of the associated pathways mentioned above holds the potential for drug targets for side effects mitigation." @default.
- W3204548832 created "2021-10-11" @default.
- W3204548832 creator A5079331432 @default.
- W3204548832 date "2021-10-04" @default.
- W3204548832 modified "2023-10-14" @default.
- W3204548832 title "Metabolomic Studies for Metabolic Alterations Induced by Non-Steroidal Anti-Inflammatory Drugs: Mini Review" @default.
- W3204548832 cites W1497420961 @default.
- W3204548832 cites W1509533903 @default.
- W3204548832 cites W1761787460 @default.
- W3204548832 cites W1818341268 @default.
- W3204548832 cites W1881405764 @default.
- W3204548832 cites W1943350258 @default.
- W3204548832 cites W1968430975 @default.
- W3204548832 cites W1969207939 @default.
- W3204548832 cites W1980168514 @default.
- W3204548832 cites W1983398430 @default.
- W3204548832 cites W1994684867 @default.
- W3204548832 cites W1999854663 @default.
- W3204548832 cites W2000065315 @default.
- W3204548832 cites W2007803420 @default.
- W3204548832 cites W2010680706 @default.
- W3204548832 cites W2023505270 @default.
- W3204548832 cites W2026804604 @default.
- W3204548832 cites W2033783179 @default.
- W3204548832 cites W2062090250 @default.
- W3204548832 cites W2067051001 @default.
- W3204548832 cites W2071052067 @default.
- W3204548832 cites W2083117078 @default.
- W3204548832 cites W2089181989 @default.
- W3204548832 cites W2097111776 @default.
- W3204548832 cites W2100135297 @default.
- W3204548832 cites W2115592362 @default.
- W3204548832 cites W2133154239 @default.
- W3204548832 cites W2141328173 @default.
- W3204548832 cites W2146488171 @default.
- W3204548832 cites W2155792000 @default.
- W3204548832 cites W2167118827 @default.
- W3204548832 cites W2320681728 @default.
- W3204548832 cites W2330496155 @default.
- W3204548832 cites W2340617137 @default.
- W3204548832 cites W2549531757 @default.
- W3204548832 cites W2587034866 @default.
- W3204548832 cites W2630845936 @default.
- W3204548832 cites W2737267342 @default.
- W3204548832 cites W2772755903 @default.
- W3204548832 cites W2792893019 @default.
- W3204548832 cites W2912380490 @default.
- W3204548832 cites W2921131244 @default.
- W3204548832 cites W2938555337 @default.
- W3204548832 cites W2945486404 @default.
- W3204548832 cites W2955080078 @default.
- W3204548832 cites W2967929447 @default.
- W3204548832 cites W3008727168 @default.
- W3204548832 cites W3011759777 @default.
- W3204548832 cites W3107584754 @default.
- W3204548832 doi "https://doi.org/10.3390/biom11101456" @default.
- W3204548832 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8533408" @default.
- W3204548832 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34680089" @default.
- W3204548832 hasPublicationYear "2021" @default.
- W3204548832 type Work @default.
- W3204548832 sameAs 3204548832 @default.
- W3204548832 citedByCount "7" @default.
- W3204548832 countsByYear W32045488322022 @default.
- W3204548832 countsByYear W32045488322023 @default.
- W3204548832 crossrefType "journal-article" @default.
- W3204548832 hasAuthorship W3204548832A5079331432 @default.
- W3204548832 hasBestOaLocation W32045488321 @default.
- W3204548832 hasConcept C126322002 @default.
- W3204548832 hasConcept C192989942 @default.
- W3204548832 hasConcept C21565614 @default.
- W3204548832 hasConcept C2777628954 @default.
- W3204548832 hasConcept C2779944601 @default.
- W3204548832 hasConcept C2780035454 @default.
- W3204548832 hasConcept C60644358 @default.
- W3204548832 hasConcept C62231903 @default.
- W3204548832 hasConcept C71924100 @default.
- W3204548832 hasConcept C86803240 @default.
- W3204548832 hasConcept C98274493 @default.
- W3204548832 hasConceptScore W3204548832C126322002 @default.
- W3204548832 hasConceptScore W3204548832C192989942 @default.
- W3204548832 hasConceptScore W3204548832C21565614 @default.
- W3204548832 hasConceptScore W3204548832C2777628954 @default.
- W3204548832 hasConceptScore W3204548832C2779944601 @default.
- W3204548832 hasConceptScore W3204548832C2780035454 @default.
- W3204548832 hasConceptScore W3204548832C60644358 @default.
- W3204548832 hasConceptScore W3204548832C62231903 @default.
- W3204548832 hasConceptScore W3204548832C71924100 @default.
- W3204548832 hasConceptScore W3204548832C86803240 @default.
- W3204548832 hasConceptScore W3204548832C98274493 @default.
- W3204548832 hasIssue "10" @default.
- W3204548832 hasLocation W32045488321 @default.
- W3204548832 hasLocation W32045488322 @default.
- W3204548832 hasLocation W32045488323 @default.
- W3204548832 hasLocation W32045488324 @default.
- W3204548832 hasOpenAccess W3204548832 @default.
- W3204548832 hasPrimaryLocation W32045488321 @default.
- W3204548832 hasRelatedWork W1854805732 @default.
- W3204548832 hasRelatedWork W2026428328 @default.