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• W3204594037 abstract "Medication-related osteonecrosis of the jaw (MRONJ) occurs after exposure to medication (antiresorptive or antiangiogenic agents) for bone-related complications. It is more common in the mandible than in the maxilla. The present study investigated maxillary MRONJ in elderly patients through a meta-analysis.Keywords, including MRONJ, maxilla, and surgery, were entered into databases, including Embase, PubMed/MEDLINE, Cochrane Library, and ProQuest, which were searched systematically.Investigating 77 studies, we found that 18 (2 case reports and 16 case series) papers conformed to the standards. The results revealed a 2.6:1 female-to-male ratio of disease occurrence. The average age of patients was 70.6 ± 5.5 years, and most patients were in the third stage (43.6%). The average time of medication usage was 50.0 ± 20.1 months. The pooled proportion of clinical efficacy of surgery was 86%.To prevent and manage MRONJ, all elderly patients should maintain proper oral hygiene and receive dental examinations regularly. Risk assessment and safety management of MRONJ should be performed by medical teams." @default.
• W3204594037 created "2021-10-11" @default.
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• W3204594037 date "2021-09-29" @default.
• W3204594037 modified "2023-09-26" @default.
• W3204594037 title "Investigation of the Effectiveness of Surgical Treatment on Maxillary Medication-Related Osteonecrosis of the Jaw: A Literature Review" @default.
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• W3204594037 doi "https://doi.org/10.3390/jcm10194480" @default.
• W3204594037 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8509137" @default.
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