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• W3204643238 endingPage "1333" @default.
• W3204643238 startingPage "1333" @default.
• W3204643238 abstract "The retinal pigment epithelium (RPE) is the major source of cytokines in the retina regulating the intraocular immune environment, and a primary target of photodamage. Here, we examined 27 types of cytokines secreted by ARPE-19 cells exposed to visible light and incubated with aflibercept or ranibizumab, which are two anti-vascular endothelial growth factor (VEGF) antibodies. The cells were cultured for 24 h in the dark or under 2000 lux irradiation from a daylight-colored fluorescent lamp, and cytokine levels in the culture supernatant were measured. In the light-irradiated culture, the levels of IL-9, IL-17A and bFGF were higher, and the levels of IL-6, IL-7, IL-8 and MCP-1 were lower than those in the dark culture, while there was no significant difference with the VEGF-A level. In subgroup analyses of the light-irradiated culture, the bFGF level under 250 to 2000 lux irradiation was elevated in a light intensity-dependent manner. In culture exposed to blue, green or red light, the bFGF level was elevated by blue light and was high compared to that by green or red light. In culture with aflibercept or ranibizumab in the dark, the levels of IL-6, IL-8, bFGF and MCP-1 were increased, and the IL-12 level decreased synchronously with a reduction in the VEGF-A level. Our findings indicate that continuous irradiation of visible light and VEGF suppression may be an influential factor in expression patterns of inflammatory cytokines secreted by human RPE cells." @default.
• W3204643238 created "2021-10-11" @default.
• W3204643238 creator A5018196339 @default.
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• W3204643238 creator A5062934596 @default.
• W3204643238 date "2021-09-27" @default.
• W3204643238 modified "2023-10-18" @default.
• W3204643238 title "Profiles of Cytokines Secreted by ARPE-19 Cells Exposed to Light and Incubated with Anti-VEGF Antibody" @default.
• W3204643238 cites W100155009 @default.
• W3204643238 cites W1516250834 @default.
• W3204643238 cites W1518208652 @default.
• W3204643238 cites W1533421263 @default.
• W3204643238 cites W1775118133 @default.
• W3204643238 cites W1892356714 @default.
• W3204643238 cites W191994076 @default.
• W3204643238 cites W1969406167 @default.
• W3204643238 cites W1970017835 @default.
• W3204643238 cites W1970847065 @default.
• W3204643238 cites W1975954480 @default.
• W3204643238 cites W1978340549 @default.
• W3204643238 cites W1979423929 @default.
• W3204643238 cites W1979600366 @default.
• W3204643238 cites W1987429671 @default.
• W3204643238 cites W1988655325 @default.
• W3204643238 cites W1995808454 @default.
• W3204643238 cites W2000770184 @default.
• W3204643238 cites W2006274722 @default.
• W3204643238 cites W2010880469 @default.
• W3204643238 cites W2018398696 @default.
• W3204643238 cites W2020846964 @default.
• W3204643238 cites W2021122140 @default.
• W3204643238 cites W2021814263 @default.
• W3204643238 cites W2027716003 @default.
• W3204643238 cites W2032754482 @default.
• W3204643238 cites W2037373653 @default.
• W3204643238 cites W2044699243 @default.
• W3204643238 cites W2046208657 @default.
• W3204643238 cites W2047393488 @default.
• W3204643238 cites W2047814322 @default.
• W3204643238 cites W2049848487 @default.
• W3204643238 cites W2051241024 @default.
• W3204643238 cites W2059000778 @default.
• W3204643238 cites W2060552070 @default.
• W3204643238 cites W2066360965 @default.
• W3204643238 cites W2068104033 @default.
• W3204643238 cites W2075551125 @default.
• W3204643238 cites W2076198447 @default.
• W3204643238 cites W2080946103 @default.
• W3204643238 cites W2085960334 @default.
• W3204643238 cites W2087102885 @default.
• W3204643238 cites W2099610571 @default.
• W3204643238 cites W2100190333 @default.
• W3204643238 cites W2120822810 @default.
• W3204643238 cites W2124423357 @default.
• W3204643238 cites W2127915130 @default.
• W3204643238 cites W2131744032 @default.
• W3204643238 cites W2133685524 @default.
• W3204643238 cites W2144839999 @default.
• W3204643238 cites W2166984623 @default.
• W3204643238 cites W2170037335 @default.
• W3204643238 cites W2178483454 @default.
• W3204643238 cites W2235976842 @default.
• W3204643238 cites W2346039638 @default.
• W3204643238 cites W2400484325 @default.
• W3204643238 cites W2411031570 @default.
• W3204643238 cites W2507267592 @default.
• W3204643238 cites W2605167569 @default.
• W3204643238 cites W2624707974 @default.
• W3204643238 cites W2748837275 @default.
• W3204643238 cites W2766775513 @default.
• W3204643238 cites W2784324929 @default.
• W3204643238 cites W2787724467 @default.
• W3204643238 cites W2789665178 @default.
• W3204643238 cites W2795873553 @default.
• W3204643238 cites W2809866193 @default.
• W3204643238 cites W2945489406 @default.
• W3204643238 cites W2945809410 @default.
• W3204643238 cites W2987816919 @default.
• W3204643238 cites W2995624284 @default.
• W3204643238 cites W3192568295 @default.
• W3204643238 cites W373873944 @default.
• W3204643238 cites W4211044526 @default.
• W3204643238 cites W4230886463 @default.
• W3204643238 cites W4247072832 @default.
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• W3204643238 doi "https://doi.org/10.3390/biomedicines9101333" @default.
• W3204643238 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8533158" @default.
• W3204643238 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34680450" @default.
• W3204643238 hasPublicationYear "2021" @default.
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