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• W3204649462 abstract "The role of fine-needle aspiration cytology (FNAC) is well established for preoperative evaluation of patients with salivary gland lesions. However, the lack of a uniform system for salivary gland FNAC has limited its effectiveness. In recent years, the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) has been in use around the world to report the cytology results. We aimed to investigate the efficacy and accuracy of FNAC examined according to pre-MSRSGC era dichotomous benign/malignant classification in salivary gland tumors.Patients who underwent surgery between January 2011 and December 2020 due to major salivary gland tumors were retrospectively analyzed. Two hundred and four patients were included in the analysis. Preoperative FNAC results and final histopatological diagnoses were grouped as benign or malignant. Final histopatological diagnoses were compared with the preoperative FNAC results. Also, sensitivity, specificity, and accuracy of the preoperative FNAC results, as well as the agreement between both tests were investigated.The sensitivity, specificity, accuracy, positive and negative predictive values of the preoperative FNAC for the diagnosis of malignancy were 59.09%, 97.85%, 93.75%, 76.47%, and 95.29%, respectively. There was a moderate agreement between the preoperative FNAC results and final histopatological diagnoses.The accuracy of the preoperative FNAC and the information given about malignancy risk are the most important criteria for patient management and decision-making. The MSRSGC, which consists of a six-tiered classification rather than a dichotomous yes/no system, may contribute to patient management and decision-making by increasing the efficacy and accuracy of FNAC.Tükürük bezi lezyonları olan hastaların preoperatif değerlendirilmesinde ince iğne aspirasyon sitolojisinin (İİAS) rolü iyi bilinmektedir. Ancak tükürük bezi İİAS için tek tip bir sistemin olmaması etkinliğini sınırlamıştır. Son yıllarda tükürük bezi sitopatolojisini raporlamak için oluşturulan Milan sistemi (MS) dünya çapında kullanılmaktadır. Çalışmamızda tükürük bezi tümörlerinin MS öncesi ikili benign/malign sınıflamasına göre incelenen İİAS sonuçlarının etkinliğini ve doğruluğunu araştırmayı amaçladık.Ocak 2011-Aralık 2020 tarihleri arasında majör tükürük bezi tümörü nedeniyle ameliyat edilen hastalar retrospektif olarak tarandı. Çalışmaya 204 hasta dahil edildi. Preoperatif İİAS sonuçları ve nihai histopatolojik tanılar benign ve malign olarak gruplandırıldı. Nihai histopatolojik tanılar, preoperatif İİAS sonuçları ile karşılaştırıldı ve preoperatif İİAS sonuçlarının duyarlılığı, özgüllüğü, doğruluğu ve her iki test arasındaki uyum araştırıldı.Malignite tanısı için preoperatif İİAS’nin duyarlılığı %59,09, özgüllüğü %97,85, doğruluğu %93,75, pozitif prediktif değeri %76,47 ve negatif prediktif değeri %95,29 idi. Preoperatif İİAS sonuçları ile nihai histopatolojik tanı arasında orta derecede bir uyum vardı.Preoperatif İİAS’nin doğruluğu ve malignite riski hakkında verdiği bilgiler hasta yönetimi ve karar vermede en önemli kriterlerdir. İkili bir “evet/hayır” sisteminden ziyade altı katmanlı bir sınıflandırmadan oluşan MS, İİAS’nin etkinliğini ve doğruluğunu artırarak hasta yönetimine ve karar vermeye katkıda bulunabilir." @default.
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• W3204649462 date "2021-01-01" @default.
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• W3204649462 title "Fine-Needle Aspiration Cytology of Salivary Gland Tumors Before the Milan System: Ten Years of Experience at a Tertiary Care Center in Turkey" @default.
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• W3204649462 doi "https://doi.org/10.5222/mmj.2021.90912" @default.
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