FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204657321> ?p ?o ?g. }

• W3204657321 endingPage "252" @default.
• W3204657321 startingPage "239" @default.
• W3204657321 abstract "Nigella sativa is famous for its usefulness in a wide range of diseases and disorders since ancient times. Numerous plant-derived products play an important role in promoting cardiac health. N. sativa is the name of a plant whose seeds are well known for their medicinal uses in many Middle East, Asian, and far Eastern countries. These plants are mainly found in North Africa, Indian subcontinent and Western Asia (Eric Y. and Kathy A., 2014). N. sativa is the part of kingdom Plantae and family of flowering plants known as Ranunculaceae. It is also known by many names such as black seed or kalonji. This plant has many active ingredients such as amino acids, proteins, carbohydrates, and some volatile oils (Fatemah et al., 2014). Among these, thymoquinone (TQ) is one of the active ingredients of N. sativa (Oskouei et al., 2018). It is well known for its usefulness in cardiovascular diseases (CVDs). CVDs form the single largest cause of early mortality in developed as well as developing countries at an alarming rate. TQ and N. sativa as a whole have a protective role on a wide range of metabolic and cardiac diseases. This is mainly due to its rich flavonoid and antioxidant content. A balance between free radical injury and antioxidant intake helps our body’s defense mechanism to overcome different forms of oxidative stress. TQ may prove as a useful substance that may help in improvement of biochemical imbalances in human body. It has been observed in different studies that TQ efficiently improved CVD by declining β-hydroxy β-methylglutaryl coenzyme A (HMG-CoA) reductase activity and hence lowering the total cholesterol levels. Studies have shown that TQ decreases mean arterial blood pressure and heart rate in hypertensive rats. Biochemically, fatty acids like linoleic acid, oleic acid, palmitic acid have been found in N. sativa derivatives. Various aromatic constituents such as TQ, dihydrothymoquinone, thymol, carvacrol, and different alkaloids are also present in N. Sativa. Antioxidant properties of its various components make it a useful substance. The main precursor for build-up of oxidative stress is reactive oxygen species (ROS) formation in excess amounts. This is due to oxidation of various biomolecules and adds on to the vascular changes in the heart and damage to vessels. TQ is well known for its role in CVDs. Various studies have shown that TQ promotes and boosts heart health. Antioxidant defense mechanisms of our body fail to balance this surplus ROS production; hence, produce oxidative stress. Oxidative stress is the major culprit for various metabolic disorders like CVDs, systemic hypertension, diabetes mellitus, etc. In this chapter, we have discussed how N. Sativa intake can help in prevention of cardiovascular disorders that is becoming a major cause of mortality and morbidity worldwide." @default.
• W3204657321 created "2021-10-11" @default.
• W3204657321 creator A5010361277 @default.
• W3204657321 creator A5017886372 @default.
• W3204657321 creator A5046968453 @default.
• W3204657321 creator A5082513801 @default.
• W3204657321 creator A5087494094 @default.
• W3204657321 date "2022-01-01" @default.
• W3204657321 modified "2023-09-25" @default.
• W3204657321 title "The cardioprotective effect of thymoquinone from Nigella sativa" @default.
• W3204657321 cites W1522088041 @default.
• W3204657321 cites W1963794988 @default.
• W3204657321 cites W1968094414 @default.
• W3204657321 cites W1998354469 @default.
• W3204657321 cites W2006231374 @default.
• W3204657321 cites W2016903551 @default.
• W3204657321 cites W2023390659 @default.
• W3204657321 cites W2030686160 @default.
• W3204657321 cites W2033549134 @default.
• W3204657321 cites W2049042850 @default.
• W3204657321 cites W2052356211 @default.
• W3204657321 cites W2056899865 @default.
• W3204657321 cites W2061668355 @default.
• W3204657321 cites W2073646221 @default.
• W3204657321 cites W2074557486 @default.
• W3204657321 cites W2075995458 @default.
• W3204657321 cites W2088383768 @default.
• W3204657321 cites W2116984056 @default.
• W3204657321 cites W2163577587 @default.
• W3204657321 cites W2168630917 @default.
• W3204657321 cites W2308417021 @default.
• W3204657321 cites W2335459455 @default.
• W3204657321 cites W2388825753 @default.
• W3204657321 cites W2468931153 @default.
• W3204657321 cites W2761954664 @default.
• W3204657321 cites W2794488283 @default.
• W3204657321 cites W2809173583 @default.
• W3204657321 cites W2809390669 @default.
• W3204657321 cites W2809608655 @default.
• W3204657321 cites W4211206238 @default.
• W3204657321 cites W4234467251 @default.
• W3204657321 doi "https://doi.org/10.1016/b978-0-12-824462-3.00006-8" @default.
• W3204657321 hasPublicationYear "2022" @default.
• W3204657321 type Work @default.
• W3204657321 sameAs 3204657321 @default.
• W3204657321 citedByCount "3" @default.
• W3204657321 countsByYear W32046573212022 @default.
• W3204657321 countsByYear W32046573212023 @default.
• W3204657321 crossrefType "book-chapter" @default.
• W3204657321 hasAuthorship W3204657321A5010361277 @default.
• W3204657321 hasAuthorship W3204657321A5017886372 @default.
• W3204657321 hasAuthorship W3204657321A5046968453 @default.
• W3204657321 hasAuthorship W3204657321A5082513801 @default.
• W3204657321 hasAuthorship W3204657321A5087494094 @default.
• W3204657321 hasConcept C2778004101 @default.
• W3204657321 hasConcept C2779034068 @default.
• W3204657321 hasConcept C2779054382 @default.
• W3204657321 hasConcept C2779411416 @default.
• W3204657321 hasConcept C2993714443 @default.
• W3204657321 hasConcept C55493867 @default.
• W3204657321 hasConcept C556039675 @default.
• W3204657321 hasConcept C59822182 @default.
• W3204657321 hasConcept C71924100 @default.
• W3204657321 hasConcept C86803240 @default.
• W3204657321 hasConceptScore W3204657321C2778004101 @default.
• W3204657321 hasConceptScore W3204657321C2779034068 @default.
• W3204657321 hasConceptScore W3204657321C2779054382 @default.
• W3204657321 hasConceptScore W3204657321C2779411416 @default.
• W3204657321 hasConceptScore W3204657321C2993714443 @default.
• W3204657321 hasConceptScore W3204657321C55493867 @default.
• W3204657321 hasConceptScore W3204657321C556039675 @default.
• W3204657321 hasConceptScore W3204657321C59822182 @default.
• W3204657321 hasConceptScore W3204657321C71924100 @default.
• W3204657321 hasConceptScore W3204657321C86803240 @default.
• W3204657321 hasLocation W32046573211 @default.
• W3204657321 hasOpenAccess W3204657321 @default.
• W3204657321 hasPrimaryLocation W32046573211 @default.
• W3204657321 hasRelatedWork W2154853392 @default.
• W3204657321 hasRelatedWork W2512032932 @default.
• W3204657321 hasRelatedWork W2949567254 @default.
• W3204657321 hasRelatedWork W3034233896 @default.
• W3204657321 hasRelatedWork W3214710153 @default.
• W3204657321 hasRelatedWork W4292553122 @default.
• W3204657321 hasRelatedWork W4294363584 @default.
• W3204657321 hasRelatedWork W4308810387 @default.
• W3204657321 hasRelatedWork W2187138187 @default.
• W3204657321 hasRelatedWork W2187154978 @default.
• W3204657321 isParatext "false" @default.
• W3204657321 isRetracted "false" @default.
• W3204657321 magId "3204657321" @default.
• W3204657321 workType "book-chapter" @default.