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- W3204658561 abstract "Predicting functional outcomes after surgery and early adjuvant treatment is difficult due to the complex, extended, interlocking brain networks that underpin cognition. The aim of this study was to test glioma functional interactions with the rest of the brain, thereby identifying the risk factors of cognitive recovery or deterioration. Seventeen patients with diffuse non-enhancing glioma (aged 22-56 years) were longitudinally MRI scanned and cognitively assessed before and after surgery and during a 12-month recovery period (55 MRI scans in total after exclusions). We initially found, and then replicated in an independent dataset, that the spatial correlation pattern between regional and global BOLD signals (also known as global signal topography) was associated with tumour occurrence. We then estimated the coupling between the BOLD signal from within the tumour and the signal extracted from different brain tissues. We observed that the normative global signal topography is reorganised in glioma patients during the recovery period. Moreover, we found that the BOLD signal within the tumour and lesioned brain was coupled with the global signal and that this coupling was associated with cognitive recovery. Nevertheless, patients did not show any apparent disruption of functional connectivity within canonical functional networks. Understanding how tumour infiltration and coupling are related to patients' recovery represents a major step forward in prognostic development." @default.
- W3204658561 created "2021-10-11" @default.
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- W3204658561 date "2021-10-06" @default.
- W3204658561 modified "2023-10-01" @default.
- W3204658561 title "BOLD Coupling between Lesioned and Healthy Brain Is Associated with Glioma Patients’ Recovery" @default.
- W3204658561 cites W1518415016 @default.
- W3204658561 cites W1573066718 @default.
- W3204658561 cites W1764926271 @default.
- W3204658561 cites W1976576973 @default.
- W3204658561 cites W1986702009 @default.
- W3204658561 cites W1987777969 @default.
- W3204658561 cites W1987804548 @default.
- W3204658561 cites W2011635108 @default.
- W3204658561 cites W2026390611 @default.
- W3204658561 cites W2027777361 @default.
- W3204658561 cites W2035809725 @default.
- W3204658561 cites W2039031131 @default.
- W3204658561 cites W2040803044 @default.
- W3204658561 cites W2043601923 @default.
- W3204658561 cites W2048034803 @default.
- W3204658561 cites W2049279611 @default.
- W3204658561 cites W2051509186 @default.
- W3204658561 cites W2052136636 @default.
- W3204658561 cites W2053108157 @default.
- W3204658561 cites W2053702121 @default.
- W3204658561 cites W2053821474 @default.
- W3204658561 cites W2057950952 @default.
- W3204658561 cites W2067006079 @default.
- W3204658561 cites W2076861721 @default.
- W3204658561 cites W2083990958 @default.
- W3204658561 cites W2093699603 @default.
- W3204658561 cites W2096891331 @default.
- W3204658561 cites W2097982135 @default.
- W3204658561 cites W2102535081 @default.
- W3204658561 cites W2102673550 @default.
- W3204658561 cites W2107499714 @default.
- W3204658561 cites W2111940175 @default.
- W3204658561 cites W2112880468 @default.
- W3204658561 cites W2117577687 @default.
- W3204658561 cites W2123155935 @default.
- W3204658561 cites W2130915922 @default.
- W3204658561 cites W2133433247 @default.
- W3204658561 cites W2143411581 @default.
- W3204658561 cites W2157446241 @default.
- W3204658561 cites W2161289668 @default.
- W3204658561 cites W2266034247 @default.
- W3204658561 cites W2290211399 @default.
- W3204658561 cites W2293496672 @default.
- W3204658561 cites W2309914605 @default.
- W3204658561 cites W2401994723 @default.
- W3204658561 cites W2409584775 @default.
- W3204658561 cites W2443496093 @default.
- W3204658561 cites W2529479229 @default.
- W3204658561 cites W2537382818 @default.
- W3204658561 cites W2557111525 @default.
- W3204658561 cites W2588517580 @default.
- W3204658561 cites W2607778875 @default.
- W3204658561 cites W2753846954 @default.
- W3204658561 cites W2783695179 @default.
- W3204658561 cites W2784793309 @default.
- W3204658561 cites W2786172279 @default.
- W3204658561 cites W2800880748 @default.
- W3204658561 cites W2888087032 @default.
- W3204658561 cites W2888589894 @default.
- W3204658561 cites W2897300209 @default.
- W3204658561 cites W2912122049 @default.
- W3204658561 cites W2921738573 @default.
- W3204658561 cites W2936112401 @default.
- W3204658561 cites W2946311545 @default.
- W3204658561 cites W2947427313 @default.
- W3204658561 cites W2950359406 @default.
- W3204658561 cites W2965808014 @default.
- W3204658561 cites W2973686658 @default.
- W3204658561 cites W2974724557 @default.
- W3204658561 cites W2977916355 @default.
- W3204658561 cites W2990595263 @default.
- W3204658561 cites W3000660920 @default.
- W3204658561 cites W3016599742 @default.
- W3204658561 cites W3021642983 @default.
- W3204658561 cites W3034100035 @default.
- W3204658561 cites W3039992887 @default.
- W3204658561 cites W3049530757 @default.
- W3204658561 cites W3081087537 @default.
- W3204658561 cites W3084589112 @default.
- W3204658561 cites W3093094717 @default.
- W3204658561 cites W3109787068 @default.