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• W3204665660 endingPage "1572" @default.
• W3204665660 startingPage "1572" @default.
• W3204665660 abstract "Porous nanomaterials (PNMs) are nanosized materials with specially designed porous structures that have been widely used in the bone tissue engineering field due to the fact of their excellent physical and chemical properties such as high porosity, high specific surface area, and ideal biodegradability. Currently, PNMs are mainly used in the following four aspects: (1) as an excellent cargo to deliver bone regenerative growth factors/drugs; (2) as a fluorescent material to trace cell differentiation and bone formation; (3) as a raw material to synthesize or modify tissue engineering scaffolds; (4) as a bio-active substance to regulate cell behavior. Recent advances in the interaction between nanomaterials and cells have revealed that autophagy, a cellular survival mechanism that regulates intracellular activity by degrading/recycling intracellular metabolites, providing energy/nutrients, clearing protein aggregates, destroying organelles, and destroying intracellular pathogens, is associated with the phagocytosis and clearance of nanomaterials as well as material-induced cell differentiation and stress. Autophagy regulates bone remodeling balance via directly participating in the differentiation of osteoclasts and osteoblasts. Moreover, autophagy can regulate bone regeneration by modulating immune cell response, thereby modulating the osteogenic microenvironment. Therefore, autophagy may serve as an effective target for nanomaterials to facilitate the bone regeneration process. Increasingly, studies have shown that PNMs can modulate autophagy to regulate bone regeneration in recent years. This paper summarizes the current advances on the main application of PNMs in bone regeneration, the critical role of autophagy in bone regeneration, and the mechanism of PNMs regulating bone regeneration by targeting autophagy." @default.
• W3204665660 created "2021-10-11" @default.
• W3204665660 creator A5032079976 @default.
• W3204665660 creator A5050407874 @default.
• W3204665660 creator A5053398400 @default.
• W3204665660 date "2021-09-28" @default.
• W3204665660 modified "2023-10-17" @default.
• W3204665660 title "Porous Nanomaterials Targeting Autophagy in Bone Regeneration" @default.
• W3204665660 cites W1023276655 @default.
• W3204665660 cites W150471657 @default.
• W3204665660 cites W1890195102 @default.
• W3204665660 cites W1929999284 @default.
• W3204665660 cites W1966632101 @default.
• W3204665660 cites W1975968586 @default.
• W3204665660 cites W1976391651 @default.
• W3204665660 cites W1980051005 @default.
• W3204665660 cites W1983467597 @default.
• W3204665660 cites W1985478291 @default.
• W3204665660 cites W2004618997 @default.
• W3204665660 cites W2020766330 @default.
• W3204665660 cites W2023465240 @default.
• W3204665660 cites W2032918292 @default.
• W3204665660 cites W2035310767 @default.
• W3204665660 cites W2036566613 @default.
• W3204665660 cites W2042602209 @default.
• W3204665660 cites W2049089797 @default.
• W3204665660 cites W2057857084 @default.
• W3204665660 cites W2059952612 @default.
• W3204665660 cites W2065396317 @default.
• W3204665660 cites W2068153705 @default.
• W3204665660 cites W2074245293 @default.
• W3204665660 cites W2074515622 @default.
• W3204665660 cites W2074906434 @default.
• W3204665660 cites W2075021091 @default.
• W3204665660 cites W2077796307 @default.
• W3204665660 cites W2078410459 @default.
• W3204665660 cites W2078616336 @default.
• W3204665660 cites W2079025550 @default.
• W3204665660 cites W2081057817 @default.
• W3204665660 cites W2084964187 @default.
• W3204665660 cites W2087306921 @default.
• W3204665660 cites W2089264492 @default.
• W3204665660 cites W2090688353 @default.
• W3204665660 cites W2093682086 @default.
• W3204665660 cites W2095529451 @default.
• W3204665660 cites W2101873325 @default.
• W3204665660 cites W2102009801 @default.
• W3204665660 cites W2126598569 @default.
• W3204665660 cites W2129142858 @default.
• W3204665660 cites W2131007152 @default.
• W3204665660 cites W2135573857 @default.
• W3204665660 cites W2135799879 @default.
• W3204665660 cites W2136394786 @default.
• W3204665660 cites W2152752812 @default.
• W3204665660 cites W2162738730 @default.
• W3204665660 cites W2175779306 @default.
• W3204665660 cites W2194806179 @default.
• W3204665660 cites W2284254157 @default.
• W3204665660 cites W2291429897 @default.
• W3204665660 cites W2300173132 @default.
• W3204665660 cites W2301813316 @default.
• W3204665660 cites W2329963269 @default.
• W3204665660 cites W2331583349 @default.
• W3204665660 cites W2492928776 @default.
• W3204665660 cites W2509957117 @default.
• W3204665660 cites W2516080680 @default.
• W3204665660 cites W2530092652 @default.
• W3204665660 cites W2532062469 @default.
• W3204665660 cites W2554813560 @default.
• W3204665660 cites W2558213513 @default.
• W3204665660 cites W2565783764 @default.
• W3204665660 cites W2570352744 @default.
• W3204665660 cites W2579686003 @default.
• W3204665660 cites W2582865844 @default.
• W3204665660 cites W2584188058 @default.
• W3204665660 cites W2591791011 @default.
• W3204665660 cites W2592963371 @default.
• W3204665660 cites W2596197437 @default.
• W3204665660 cites W2602339215 @default.
• W3204665660 cites W2604341750 @default.
• W3204665660 cites W2606910875 @default.
• W3204665660 cites W2609931305 @default.
• W3204665660 cites W2738460563 @default.
• W3204665660 cites W2761809061 @default.
• W3204665660 cites W2772886550 @default.
• W3204665660 cites W2774746972 @default.
• W3204665660 cites W2775034467 @default.
• W3204665660 cites W2782402282 @default.
• W3204665660 cites W2791470310 @default.
• W3204665660 cites W2792643378 @default.
• W3204665660 cites W2802607353 @default.
• W3204665660 cites W2804267945 @default.
• W3204665660 cites W2804789690 @default.
• W3204665660 cites W2807575241 @default.
• W3204665660 cites W2808643980 @default.
• W3204665660 cites W2883239340 @default.
• W3204665660 cites W2884010813 @default.
• W3204665660 cites W2887649335 @default.

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