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• W3204690407 abstract "A two-chamber inflation-deflation test was recently proposed as a diagnostic method to determine parameters of the intermittent pneumatic compression used as an effective therapeutic modality for lymphedematous limbs. It is crucial that the recorded trends for residual tissue deformations are understood in terms of specific properties of subcutaneous tissue and skin to support diagnostic process. This paper presents a mechanical model of lymphedematous legs in two-chamber tests. The cylindrical geometry composed of layers of skin, modeled as hyperelastic medium, and subcutaneous tissue, modeled as fluid saturated hyperporoelastic medium, is assumed. The results of finite element simulations show the possibility of such combinations of the properties of skin (rigidity) and subcutaneous tissue (rigidity and permeability), which ensures that the model predictions resemble the evolution of tissue residual deformations observed in the two-chamber test. The stiffness and permeability appeared to be the most crucial tissue property determining trend lines of residual deformations. The analysis of the components of displacement of solid matrix and pore fluid pressure explains the mechanisms that are responsible for particular tissue behavior. The moderate role of skin and limitations related to the mechanical and geometrical model assumptions are indicated. Recommendations for treating lymphedema using intermittent compression therapy in relation to the results of the two-chamber test and properties of tissues are discussed." @default.
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• W3204690407 date "2021-10-18" @default.
• W3204690407 modified "2023-10-16" @default.
• W3204690407 title "Simulation‐based reasoning of residual tissue deformations in a two‐chamber test of a lymphedematous leg" @default.
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• W3204690407 doi "https://doi.org/10.1002/cnm.3537" @default.
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