Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204692008> ?p ?o ?g. }
- W3204692008 endingPage "1699" @default.
- W3204692008 startingPage "1685" @default.
- W3204692008 abstract "Several studies have evaluated prophylactic emollients as a preventive strategy against atopic dermatitis (AD) and food allergy (FA). We aimed to synthesize the evidence on efficacy and safety of prophylactic emollients started during the first 6 weeks of infancy for prevention of AD and FA.MEDLINE, Embase, CINAHL, BIOSIS, and the Cochrane Library databases were searched systematically for randomized controlled trials published between January 2000 and July 2020, which assessed the effects of prophylactic emollients initiated within the first 6 weeks of life on the development of AD within 24 months of age, compared to no treatment. Risk of bias and certainty of evidence were assessed using the Cochrane Collaboration's tool and GRADE process, respectively.Of the 1486 articles identified, 10 studies fulfilled inclusion criteria. In infants given emollients, there was no significant reduction on the development of AD (risk ratio (RR) 0.84, 95% confidence interval (CI) 0.64, 1.10) compared to the control group. However, there was significant benefit of prophylactic emollients (RR 0.75, 95% CI 0.62-1.11) in the high-risk population (n = 8 studies). There was also significant benefit (RR 0.59, 95% CI 0.43, 0.81) in studies (n = 6) where emollients were used continuously to the point of AD assessment; but not when treatment was ceased for an interval before AD assessment. There were no protective effects on FA found.The prophylactic application of emollients initiated in early infancy may prevent AD, especially in high-risk populations and when used continuously. We hypothesize that emollients may delay rather than prevent AD." @default.
- W3204692008 created "2021-10-11" @default.
- W3204692008 creator A5026001698 @default.
- W3204692008 creator A5042477874 @default.
- W3204692008 creator A5052143160 @default.
- W3204692008 creator A5070045006 @default.
- W3204692008 date "2021-10-12" @default.
- W3204692008 modified "2023-10-02" @default.
- W3204692008 title "Emollients in infancy to prevent atopic dermatitis: A systematic review and meta‐analysis" @default.
- W3204692008 cites W1605295219 @default.
- W3204692008 cites W1862789108 @default.
- W3204692008 cites W2030480507 @default.
- W3204692008 cites W2075771479 @default.
- W3204692008 cites W2082217757 @default.
- W3204692008 cites W2098923148 @default.
- W3204692008 cites W2137411170 @default.
- W3204692008 cites W2142327072 @default.
- W3204692008 cites W2157425698 @default.
- W3204692008 cites W2161701454 @default.
- W3204692008 cites W2165676713 @default.
- W3204692008 cites W2491693483 @default.
- W3204692008 cites W2548214199 @default.
- W3204692008 cites W2560647422 @default.
- W3204692008 cites W2617727916 @default.
- W3204692008 cites W2759745678 @default.
- W3204692008 cites W2763299551 @default.
- W3204692008 cites W2895477658 @default.
- W3204692008 cites W2950267780 @default.
- W3204692008 cites W2956405909 @default.
- W3204692008 cites W2970684805 @default.
- W3204692008 cites W2976709398 @default.
- W3204692008 cites W2999949761 @default.
- W3204692008 cites W3007130141 @default.
- W3204692008 cites W3009019417 @default.
- W3204692008 cites W3097210006 @default.
- W3204692008 cites W4294215472 @default.
- W3204692008 doi "https://doi.org/10.1111/all.15116" @default.
- W3204692008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34591995" @default.
- W3204692008 hasPublicationYear "2021" @default.
- W3204692008 type Work @default.
- W3204692008 sameAs 3204692008 @default.
- W3204692008 citedByCount "27" @default.
- W3204692008 countsByYear W32046920082022 @default.
- W3204692008 countsByYear W32046920082023 @default.
- W3204692008 crossrefType "journal-article" @default.
- W3204692008 hasAuthorship W3204692008A5026001698 @default.
- W3204692008 hasAuthorship W3204692008A5042477874 @default.
- W3204692008 hasAuthorship W3204692008A5052143160 @default.
- W3204692008 hasAuthorship W3204692008A5070045006 @default.
- W3204692008 hasConcept C126322002 @default.
- W3204692008 hasConcept C141071460 @default.
- W3204692008 hasConcept C16005928 @default.
- W3204692008 hasConcept C168563851 @default.
- W3204692008 hasConcept C17744445 @default.
- W3204692008 hasConcept C187212893 @default.
- W3204692008 hasConcept C189708586 @default.
- W3204692008 hasConcept C199539241 @default.
- W3204692008 hasConcept C203014093 @default.
- W3204692008 hasConcept C207480886 @default.
- W3204692008 hasConcept C2776478404 @default.
- W3204692008 hasConcept C2778329239 @default.
- W3204692008 hasConcept C2779473830 @default.
- W3204692008 hasConcept C2908647359 @default.
- W3204692008 hasConcept C44249647 @default.
- W3204692008 hasConcept C71924100 @default.
- W3204692008 hasConcept C82789193 @default.
- W3204692008 hasConcept C95190672 @default.
- W3204692008 hasConcept C99454951 @default.
- W3204692008 hasConceptScore W3204692008C126322002 @default.
- W3204692008 hasConceptScore W3204692008C141071460 @default.
- W3204692008 hasConceptScore W3204692008C16005928 @default.
- W3204692008 hasConceptScore W3204692008C168563851 @default.
- W3204692008 hasConceptScore W3204692008C17744445 @default.
- W3204692008 hasConceptScore W3204692008C187212893 @default.
- W3204692008 hasConceptScore W3204692008C189708586 @default.
- W3204692008 hasConceptScore W3204692008C199539241 @default.
- W3204692008 hasConceptScore W3204692008C203014093 @default.
- W3204692008 hasConceptScore W3204692008C207480886 @default.
- W3204692008 hasConceptScore W3204692008C2776478404 @default.
- W3204692008 hasConceptScore W3204692008C2778329239 @default.
- W3204692008 hasConceptScore W3204692008C2779473830 @default.
- W3204692008 hasConceptScore W3204692008C2908647359 @default.
- W3204692008 hasConceptScore W3204692008C44249647 @default.
- W3204692008 hasConceptScore W3204692008C71924100 @default.
- W3204692008 hasConceptScore W3204692008C82789193 @default.
- W3204692008 hasConceptScore W3204692008C95190672 @default.
- W3204692008 hasConceptScore W3204692008C99454951 @default.
- W3204692008 hasIssue "6" @default.
- W3204692008 hasLocation W32046920081 @default.
- W3204692008 hasLocation W32046920082 @default.
- W3204692008 hasOpenAccess W3204692008 @default.
- W3204692008 hasPrimaryLocation W32046920081 @default.
- W3204692008 hasRelatedWork W1885119863 @default.
- W3204692008 hasRelatedWork W1996551696 @default.
- W3204692008 hasRelatedWork W2217553306 @default.
- W3204692008 hasRelatedWork W2748167152 @default.
- W3204692008 hasRelatedWork W3030276453 @default.
- W3204692008 hasRelatedWork W3041936563 @default.