Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204692099> ?p ?o ?g. }
- W3204692099 abstract "Pelvic radiotherapy is the key treatment for pelvic malignancies, usually including pelvic primary tumour lesions and lymphatic drainage areas in the pelvic region. Therefore, the intestinal tract in the radiation field is inevitably damaged, a phenomenon clinically referred to as radiation enteritis, and diarrhoea is the most common clinical symptom of radiation enteritis. Therefore, it is necessary to study the mechanism of radiation-induced diarrhoea. It has been found that the gut microbiome plays an important role in the development of diarrhoea in response to pelvic radiotherapy, and the species and distribution of intestinal microbiota are significantly altered in patients after pelvic radiotherapy. In this study, we searched for articles indexed in the Cochrane Library, Web of Science, EMBASE and PubMed databases in English and CNKI, Wanfang data and SINOMED in Chinese from their inception dates through 13 March 2020 to collect studies on the gut microbiome in pelvic radiotherapy patients. Eventually, we included eight studies: one study report on prostatic carcinoma, five studies on gynaecological carcinoma and two papers on pelvic carcinomas. All studies were designed as self-controlled studies, except for one that compared toxicity to nontoxicity. The results from all the studies showed that the diversity of intestinal flora decreased during and after pelvic radiotherapy, and the diversity of intestinal flora decreased significantly in patients with diarrhoea after radiotherapy. Five studies observed that the community composition of the gut microbiota changed at the phylum, order or genus level before, during, and after pelvic radiotherapy at different time points. In addition, the composition of the gut microbiota before radiotherapy was different between patients with postradiotherapy diarrhoea and those without diarrhoea in five studies. However, relevant studies have not reached consistent results regarding the changes in microbiota composition. Changes in the intestinal flora induced by pelvic radiotherapy and their relationship between changes in intestinal flora and the occurrence of radiation-induced diarrhoea (RID) are discussed in this study, providing a theoretical basis for the causes of RID after pelvic radiotherapy." @default.
- W3204692099 created "2021-10-11" @default.
- W3204692099 creator A5003120434 @default.
- W3204692099 creator A5004343457 @default.
- W3204692099 creator A5015885592 @default.
- W3204692099 creator A5019129316 @default.
- W3204692099 creator A5036978105 @default.
- W3204692099 creator A5038831620 @default.
- W3204692099 creator A5042947574 @default.
- W3204692099 creator A5055823984 @default.
- W3204692099 creator A5056989901 @default.
- W3204692099 creator A5060335470 @default.
- W3204692099 creator A5063998384 @default.
- W3204692099 creator A5076215040 @default.
- W3204692099 creator A5077001501 @default.
- W3204692099 date "2021-09-25" @default.
- W3204692099 modified "2023-10-17" @default.
- W3204692099 title "The impact of pelvic radiotherapy on the gut microbiome and its role in radiation-induced diarrhoea: a systematic review" @default.
- W3204692099 cites W129238531 @default.
- W3204692099 cites W1420654867 @default.
- W3204692099 cites W1554164117 @default.
- W3204692099 cites W1680688166 @default.
- W3204692099 cites W1966423019 @default.
- W3204692099 cites W1987316876 @default.
- W3204692099 cites W2002968221 @default.
- W3204692099 cites W2066853142 @default.
- W3204692099 cites W2078326955 @default.
- W3204692099 cites W2089198008 @default.
- W3204692099 cites W2097257602 @default.
- W3204692099 cites W2097916846 @default.
- W3204692099 cites W2109331652 @default.
- W3204692099 cites W2110235509 @default.
- W3204692099 cites W2117727476 @default.
- W3204692099 cites W2126726959 @default.
- W3204692099 cites W2152970968 @default.
- W3204692099 cites W2164437838 @default.
- W3204692099 cites W2176502570 @default.
- W3204692099 cites W2413970060 @default.
- W3204692099 cites W2488133443 @default.
- W3204692099 cites W2568362468 @default.
- W3204692099 cites W2609601056 @default.
- W3204692099 cites W2621056634 @default.
- W3204692099 cites W2621909488 @default.
- W3204692099 cites W2626300127 @default.
- W3204692099 cites W2663374310 @default.
- W3204692099 cites W2753577117 @default.
- W3204692099 cites W2757174403 @default.
- W3204692099 cites W2790625311 @default.
- W3204692099 cites W2804681999 @default.
- W3204692099 cites W2809436779 @default.
- W3204692099 cites W2835635281 @default.
- W3204692099 cites W2888923564 @default.
- W3204692099 cites W2912270772 @default.
- W3204692099 cites W2913834618 @default.
- W3204692099 cites W2926337143 @default.
- W3204692099 cites W2940482094 @default.
- W3204692099 cites W2949947154 @default.
- W3204692099 cites W2965321915 @default.
- W3204692099 cites W2969355881 @default.
- W3204692099 cites W2973032531 @default.
- W3204692099 cites W2974931221 @default.
- W3204692099 cites W3002865023 @default.
- W3204692099 cites W325430807 @default.
- W3204692099 doi "https://doi.org/10.1186/s13014-021-01899-y" @default.
- W3204692099 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8466721" @default.
- W3204692099 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34563216" @default.
- W3204692099 hasPublicationYear "2021" @default.
- W3204692099 type Work @default.
- W3204692099 sameAs 3204692099 @default.
- W3204692099 citedByCount "13" @default.
- W3204692099 countsByYear W32046920992022 @default.
- W3204692099 countsByYear W32046920992023 @default.
- W3204692099 crossrefType "journal-article" @default.
- W3204692099 hasAuthorship W3204692099A5003120434 @default.
- W3204692099 hasAuthorship W3204692099A5004343457 @default.
- W3204692099 hasAuthorship W3204692099A5015885592 @default.
- W3204692099 hasAuthorship W3204692099A5019129316 @default.
- W3204692099 hasAuthorship W3204692099A5036978105 @default.
- W3204692099 hasAuthorship W3204692099A5038831620 @default.
- W3204692099 hasAuthorship W3204692099A5042947574 @default.
- W3204692099 hasAuthorship W3204692099A5055823984 @default.
- W3204692099 hasAuthorship W3204692099A5056989901 @default.
- W3204692099 hasAuthorship W3204692099A5060335470 @default.
- W3204692099 hasAuthorship W3204692099A5063998384 @default.
- W3204692099 hasAuthorship W3204692099A5076215040 @default.
- W3204692099 hasAuthorship W3204692099A5077001501 @default.
- W3204692099 hasBestOaLocation W32046920991 @default.
- W3204692099 hasConcept C126322002 @default.
- W3204692099 hasConcept C143121216 @default.
- W3204692099 hasConcept C143998085 @default.
- W3204692099 hasConcept C203014093 @default.
- W3204692099 hasConcept C2781074409 @default.
- W3204692099 hasConcept C509974204 @default.
- W3204692099 hasConcept C539455810 @default.
- W3204692099 hasConcept C60644358 @default.
- W3204692099 hasConcept C71924100 @default.
- W3204692099 hasConcept C86803240 @default.
- W3204692099 hasConcept C90924648 @default.
- W3204692099 hasConceptScore W3204692099C126322002 @default.
- W3204692099 hasConceptScore W3204692099C143121216 @default.