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- W3204695623 abstract "The unmet need for blood and its cellular components that are required in different clinical situations had led to progress in the development of artificial blood cells. In comparison with red cells and platelets, the success in the manufacturing and use of artificial white blood cell (WBC) is lacking. This is primarily because of the inability to simulate the complex multifactorial physiological processes of WBCs, and hence an infrequent demand of WBC transfusion as well. However, certain interesting synthetic approaches of the WBCs functional mimicry using micro- and nanotechnology have been successfully demonstrated. These biomimetic approaches have been demonstrated to be a successful modality for the drug delivery and immune modulation, as compared to previous synthetic approaches. A better integration involving material engineers, hematologists, and immunologists is needed for the clinical translation of these artificial leukocytes approaches." @default.
- W3204695623 created "2021-10-11" @default.
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- W3204695623 date "2022-01-01" @default.
- W3204695623 modified "2023-09-26" @default.
- W3204695623 title "Artificial white blood cells—WBC substitute" @default.
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- W3204695623 doi "https://doi.org/10.1016/b978-0-12-823971-1.00015-5" @default.
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