FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204704634> ?p ?o ?g. }

• W3204704634 endingPage "100075" @default.
• W3204704634 startingPage "100075" @default.
• W3204704634 abstract "Functional pain disorders disproportionately impact females, but most pain research in animals has been conducted in males. While there are anatomical and pharmacological sexual dimorphisms in brainstem pain-modulation circuits, the physiology of pain-modulating neurons that comprise a major functional output, the rostral ventromedial medulla (RVM), has not been explored in female animals. The goal of this study was to identify and characterize the activity of RVM cells in female, compared to male, rats. ON- and OFF-cells were identified within the RVM in females, with firing properties comparable to those described in males. In addition, both ON- and OFF-cells exhibited a sensitized response to somatic stimuli in females subjected to persistent inflammation, and both ON- and OFF-cells responded to systemically administered morphine at a dose sufficient to produce behavioral antinociception. These data demonstrate that the ON-/OFF-cell framework originally defined in males is also present in females, and that as in males, these neurons are recruited in females in persistent inflammation and by systemically administered morphine. Importantly, this work establishes a foundation for the use of female animals in studies of RVM and descending control." @default.
• W3204704634 created "2021-10-11" @default.
• W3204704634 creator A5013339955 @default.
• W3204704634 creator A5038870837 @default.
• W3204704634 creator A5090215064 @default.
• W3204704634 creator A5033535210 @default.
• W3204704634 date "2021-08-01" @default.
• W3204704634 modified "2023-10-12" @default.
• W3204704634 title "Physiological properties of pain-modulating neurons in rostral ventromedial medulla in female rats, and responses to opioid administration" @default.
• W3204704634 cites W1654586824 @default.
• W3204704634 cites W1838045633 @default.
• W3204704634 cites W1871284454 @default.
• W3204704634 cites W1966090527 @default.
• W3204704634 cites W1978532562 @default.
• W3204704634 cites W1984091569 @default.
• W3204704634 cites W1996820975 @default.
• W3204704634 cites W1997001171 @default.
• W3204704634 cites W1998139363 @default.
• W3204704634 cites W1998478339 @default.
• W3204704634 cites W2000300753 @default.
• W3204704634 cites W2000492372 @default.
• W3204704634 cites W2004551214 @default.
• W3204704634 cites W2007855905 @default.
• W3204704634 cites W2010845582 @default.
• W3204704634 cites W2013458280 @default.
• W3204704634 cites W2014920351 @default.
• W3204704634 cites W2016634891 @default.
• W3204704634 cites W2019232587 @default.
• W3204704634 cites W2024424770 @default.
• W3204704634 cites W2024484140 @default.
• W3204704634 cites W2027642651 @default.
• W3204704634 cites W2029948449 @default.
• W3204704634 cites W2030867449 @default.
• W3204704634 cites W2031772253 @default.
• W3204704634 cites W2036761672 @default.
• W3204704634 cites W2040248009 @default.
• W3204704634 cites W2057076570 @default.
• W3204704634 cites W2058262364 @default.
• W3204704634 cites W2061041929 @default.
• W3204704634 cites W2062075002 @default.
• W3204704634 cites W2064356863 @default.
• W3204704634 cites W2066329882 @default.
• W3204704634 cites W2074556173 @default.
• W3204704634 cites W2077584781 @default.
• W3204704634 cites W2080745413 @default.
• W3204704634 cites W2081518034 @default.
• W3204704634 cites W2089790065 @default.
• W3204704634 cites W2095306155 @default.
• W3204704634 cites W2101556067 @default.
• W3204704634 cites W2114136585 @default.
• W3204704634 cites W2115932978 @default.
• W3204704634 cites W2215985723 @default.
• W3204704634 cites W2329339509 @default.
• W3204704634 cites W2789902361 @default.
• W3204704634 cites W2908748245 @default.
• W3204704634 cites W2918738685 @default.
• W3204704634 cites W2979884048 @default.
• W3204704634 cites W3027482181 @default.
• W3204704634 doi "https://doi.org/10.1016/j.ynpai.2021.100075" @default.
• W3204704634 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8503581" @default.
• W3204704634 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34660937" @default.
• W3204704634 hasPublicationYear "2021" @default.
• W3204704634 type Work @default.
• W3204704634 sameAs 3204704634 @default.
• W3204704634 citedByCount "5" @default.
• W3204704634 countsByYear W32047046342022 @default.
• W3204704634 countsByYear W32047046342023 @default.
• W3204704634 crossrefType "journal-article" @default.
• W3204704634 hasAuthorship W3204704634A5013339955 @default.
• W3204704634 hasAuthorship W3204704634A5033535210 @default.
• W3204704634 hasAuthorship W3204704634A5038870837 @default.
• W3204704634 hasAuthorship W3204704634A5090215064 @default.
• W3204704634 hasBestOaLocation W32047046341 @default.
• W3204704634 hasConcept C126322002 @default.
• W3204704634 hasConcept C15490471 @default.
• W3204704634 hasConcept C15744967 @default.
• W3204704634 hasConcept C169760540 @default.
• W3204704634 hasConcept C170493617 @default.
• W3204704634 hasConcept C17291353 @default.
• W3204704634 hasConcept C2777389121 @default.
• W3204704634 hasConcept C2777659854 @default.
• W3204704634 hasConcept C2779245659 @default.
• W3204704634 hasConcept C2781063702 @default.
• W3204704634 hasConcept C551621295 @default.
• W3204704634 hasConcept C71924100 @default.
• W3204704634 hasConceptScore W3204704634C126322002 @default.
• W3204704634 hasConceptScore W3204704634C15490471 @default.
• W3204704634 hasConceptScore W3204704634C15744967 @default.
• W3204704634 hasConceptScore W3204704634C169760540 @default.
• W3204704634 hasConceptScore W3204704634C170493617 @default.
• W3204704634 hasConceptScore W3204704634C17291353 @default.
• W3204704634 hasConceptScore W3204704634C2777389121 @default.
• W3204704634 hasConceptScore W3204704634C2777659854 @default.
• W3204704634 hasConceptScore W3204704634C2779245659 @default.
• W3204704634 hasConceptScore W3204704634C2781063702 @default.
• W3204704634 hasConceptScore W3204704634C551621295 @default.
• W3204704634 hasConceptScore W3204704634C71924100 @default.
• W3204704634 hasFunder F4320332161 @default.

• next