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- W3204706010 abstract "Abstract Coca leaves (Erythroxylum coca Lamarck) and powder (5–10 g) were taken orally by human subjects in the same way as South American natives do. The cocaine, as measured by mass fragmentography, was immediately detected in the blood, reached peak concentrations from 10–150 ng ml plasma at 0.38–1.95 hours, and persisted in the plasma for more than 7 hours. Half-lives of the elimination of cocaine were calculated and ranged from 1.0 to 1.9 hours. The absorption half-lives ranged from 0.2 to 0.6 hours. The shape of the curves fits with the subjective effects reported. There is no reason to believe that the stimulating effect achieved by the use of either coca leaves or powder is not due to cocaine." @default.
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- W3204706010 date "1978-05-30" @default.
- W3204706010 modified "2023-10-03" @default.
- W3204706010 title "Cocaine in Blood of Coca Chewers" @default.
- W3204706010 doi "https://doi.org/10.5962/p.168633" @default.
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