Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204706506> ?p ?o ?g. }
- W3204706506 endingPage "1502" @default.
- W3204706506 startingPage "1502" @default.
- W3204706506 abstract "This article focused on the application scenarios of three-dimensional (3D) bioprinting and gene-editing technology in various medical fields, including gene therapy, tissue engineering, tumor microenvironment simulation, tumor model construction, cancer regulation and expression, osteogenesis, and skin and vascular regeneration, and summarizing its development prospects and shortcomings.3D bioprinting is a process based on additive manufacturing that uses biological materials as the microenvironment living cells. The scaffolds and carriers manufactured by 3D bioprinting technology provide a safe, efficient, and economical platform for genes, cells, and biomolecules. Gene modification refers to replacing, splicing, silencing, editing, controlling or inactivating genes and delivering new genes. The combination of this technology that changes cell function or cell fate or corrects endogenous mutations and 3D bioprinting technology has been widely used in various medical field.We conducted a literature search for papers published up to March 2021 on the gene modification combined with 3D bioprinting in various medical fields via PubMed, Web of Science, China National Knowledge Infrastructure (CNKI). The following medical subject heading terms were included for a MEDLINE search: 3D printing/gene editing, 3D printing/genetic modification, 3D printing/seed cell, bioprinting/gene editing, bioprinting/genetic modification, bioprinting/seed cell, scaffold/gene editing, scaffold/genetic modification, scaffold/seed cell, gene/scaffold, gene/bioprinting, gene/3D printing. Quantitative and qualitative data was extracted through interpretation of each article.We have reviewed the application scenarios of 3D bioprinting and gene-editing technology in various medical fields, it provides an efficient and accurate delivery system for personalized tumor therapy, enhancing the targeting effect while maintaining the integrity of the fabricated structure. It exhibits significant application potential in developing tumor drugs. In addition, scaffolds obtained via 3D bioprinting provide gene therapy applications for skin and bone healing and repair and inducing stem cell differentiation. It also considers the future development direction in this field, such as the emergence and development of gene printing, 4D printing. The combination of nanotechnology and gene printing may provide a new way for future disease research and treatment." @default.
- W3204706506 created "2021-10-11" @default.
- W3204706506 creator A5001352092 @default.
- W3204706506 creator A5007381079 @default.
- W3204706506 creator A5013881064 @default.
- W3204706506 creator A5019734284 @default.
- W3204706506 creator A5040465674 @default.
- W3204706506 creator A5051846946 @default.
- W3204706506 creator A5052676364 @default.
- W3204706506 date "2021-10-01" @default.
- W3204706506 modified "2023-09-29" @default.
- W3204706506 title "Narrative review of gene modification: applications in three-dimensional (3D) bioprinting" @default.
- W3204706506 cites W1505154631 @default.
- W3204706506 cites W1963979299 @default.
- W3204706506 cites W1986739318 @default.
- W3204706506 cites W1993682782 @default.
- W3204706506 cites W1998734023 @default.
- W3204706506 cites W2005506639 @default.
- W3204706506 cites W2010165954 @default.
- W3204706506 cites W2011827468 @default.
- W3204706506 cites W2017043267 @default.
- W3204706506 cites W2035120004 @default.
- W3204706506 cites W2036388896 @default.
- W3204706506 cites W2039705224 @default.
- W3204706506 cites W2048446098 @default.
- W3204706506 cites W2049226081 @default.
- W3204706506 cites W2093144236 @default.
- W3204706506 cites W2101187980 @default.
- W3204706506 cites W2111893100 @default.
- W3204706506 cites W2119498862 @default.
- W3204706506 cites W2125397490 @default.
- W3204706506 cites W2153885566 @default.
- W3204706506 cites W2216567752 @default.
- W3204706506 cites W2265139392 @default.
- W3204706506 cites W2299693612 @default.
- W3204706506 cites W2417310706 @default.
- W3204706506 cites W2521892624 @default.
- W3204706506 cites W2538639213 @default.
- W3204706506 cites W2621229065 @default.
- W3204706506 cites W2742167711 @default.
- W3204706506 cites W2776129144 @default.
- W3204706506 cites W2783359346 @default.
- W3204706506 cites W2783542638 @default.
- W3204706506 cites W2789529658 @default.
- W3204706506 cites W2795007544 @default.
- W3204706506 cites W2800845801 @default.
- W3204706506 cites W2802579798 @default.
- W3204706506 cites W2923561240 @default.
- W3204706506 cites W2941417604 @default.
- W3204706506 cites W2954894974 @default.
- W3204706506 cites W2956545950 @default.
- W3204706506 cites W2963542471 @default.
- W3204706506 cites W2971721326 @default.
- W3204706506 cites W2994819244 @default.
- W3204706506 cites W2999106070 @default.
- W3204706506 cites W3007696870 @default.
- W3204706506 cites W3014352467 @default.
- W3204706506 cites W3036229340 @default.
- W3204706506 cites W3037586672 @default.
- W3204706506 cites W3039698364 @default.
- W3204706506 cites W3087731809 @default.
- W3204706506 cites W3089396305 @default.
- W3204706506 cites W3095185855 @default.
- W3204706506 cites W3125407323 @default.
- W3204706506 cites W3133877934 @default.
- W3204706506 cites W3162661003 @default.
- W3204706506 doi "https://doi.org/10.21037/atm-21-2854" @default.
- W3204706506 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8573440" @default.
- W3204706506 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34805364" @default.
- W3204706506 hasPublicationYear "2021" @default.
- W3204706506 type Work @default.
- W3204706506 sameAs 3204706506 @default.
- W3204706506 citedByCount "3" @default.
- W3204706506 countsByYear W32047065062023 @default.
- W3204706506 crossrefType "journal-article" @default.
- W3204706506 hasAuthorship W3204706506A5001352092 @default.
- W3204706506 hasAuthorship W3204706506A5007381079 @default.
- W3204706506 hasAuthorship W3204706506A5013881064 @default.
- W3204706506 hasAuthorship W3204706506A5019734284 @default.
- W3204706506 hasAuthorship W3204706506A5040465674 @default.
- W3204706506 hasAuthorship W3204706506A5051846946 @default.
- W3204706506 hasAuthorship W3204706506A5052676364 @default.
- W3204706506 hasBestOaLocation W32047065061 @default.
- W3204706506 hasConcept C104317684 @default.
- W3204706506 hasConcept C111599444 @default.
- W3204706506 hasConcept C135983454 @default.
- W3204706506 hasConcept C141231307 @default.
- W3204706506 hasConcept C144501496 @default.
- W3204706506 hasConcept C2779718196 @default.
- W3204706506 hasConcept C41008148 @default.
- W3204706506 hasConcept C49892992 @default.
- W3204706506 hasConcept C54355233 @default.
- W3204706506 hasConcept C60644358 @default.
- W3204706506 hasConcept C70721500 @default.
- W3204706506 hasConcept C77088390 @default.
- W3204706506 hasConcept C86803240 @default.
- W3204706506 hasConcept C89429830 @default.
- W3204706506 hasConceptScore W3204706506C104317684 @default.