Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204754300> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W3204754300 abstract "Among the inheritance of cellular components during cell division, deoxyribonucleic acid (DNA) and its condensate (chromosome) are conventionally visualized using chemical tag-labeled nucleotide analogs. However, associated mutagenesis with nucleotide analogs in the visualization of chromosomes is cause for concern. This study investigated the efficiency of using stable isotope labels in visualizing the replicating cultured human cell-chromosomes, in the absence of analog labels, at a high spatial resolution of 100 nm. The distinct carbon isotope ratio between sister chromatids reflected the semi-conservative replication of individual DNA strands through cell cycles and suggested the renewal of histone molecules in daughter chromosomes. Thus, this study provides a new, powerful approach to trace and visualize cellular components with stable isotope labeling.Key words: stable isotope, chromosome replication, semi-conservative replication, imaging, mass spectrometry." @default.
- W3204754300 created "2021-10-11" @default.
- W3204754300 creator A5003193875 @default.
- W3204754300 creator A5011197966 @default.
- W3204754300 creator A5032609911 @default.
- W3204754300 creator A5034011069 @default.
- W3204754300 creator A5058167394 @default.
- W3204754300 creator A5084109152 @default.
- W3204754300 creator A5089825339 @default.
- W3204754300 date "2021-01-01" @default.
- W3204754300 modified "2023-10-14" @default.
- W3204754300 title "Visualization of DNA replication in single chromosome by stable isotope labeling" @default.
- W3204754300 doi "https://doi.org/10.1247/csf.21011" @default.
- W3204754300 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34565768" @default.
- W3204754300 hasPublicationYear "2021" @default.
- W3204754300 type Work @default.
- W3204754300 sameAs 3204754300 @default.
- W3204754300 citedByCount "0" @default.
- W3204754300 crossrefType "journal-article" @default.
- W3204754300 hasAuthorship W3204754300A5003193875 @default.
- W3204754300 hasAuthorship W3204754300A5011197966 @default.
- W3204754300 hasAuthorship W3204754300A5032609911 @default.
- W3204754300 hasAuthorship W3204754300A5034011069 @default.
- W3204754300 hasAuthorship W3204754300A5058167394 @default.
- W3204754300 hasAuthorship W3204754300A5084109152 @default.
- W3204754300 hasAuthorship W3204754300A5089825339 @default.
- W3204754300 hasBestOaLocation W32047543001 @default.
- W3204754300 hasConcept C104317684 @default.
- W3204754300 hasConcept C104690221 @default.
- W3204754300 hasConcept C1491633281 @default.
- W3204754300 hasConcept C185592680 @default.
- W3204754300 hasConcept C2778354886 @default.
- W3204754300 hasConcept C30481170 @default.
- W3204754300 hasConcept C54355233 @default.
- W3204754300 hasConcept C552990157 @default.
- W3204754300 hasConcept C73573662 @default.
- W3204754300 hasConcept C8502773 @default.
- W3204754300 hasConcept C85813293 @default.
- W3204754300 hasConcept C86803240 @default.
- W3204754300 hasConcept C95444343 @default.
- W3204754300 hasConceptScore W3204754300C104317684 @default.
- W3204754300 hasConceptScore W3204754300C104690221 @default.
- W3204754300 hasConceptScore W3204754300C1491633281 @default.
- W3204754300 hasConceptScore W3204754300C185592680 @default.
- W3204754300 hasConceptScore W3204754300C2778354886 @default.
- W3204754300 hasConceptScore W3204754300C30481170 @default.
- W3204754300 hasConceptScore W3204754300C54355233 @default.
- W3204754300 hasConceptScore W3204754300C552990157 @default.
- W3204754300 hasConceptScore W3204754300C73573662 @default.
- W3204754300 hasConceptScore W3204754300C8502773 @default.
- W3204754300 hasConceptScore W3204754300C85813293 @default.
- W3204754300 hasConceptScore W3204754300C86803240 @default.
- W3204754300 hasConceptScore W3204754300C95444343 @default.
- W3204754300 hasLocation W32047543001 @default.
- W3204754300 hasLocation W32047543002 @default.
- W3204754300 hasOpenAccess W3204754300 @default.
- W3204754300 hasPrimaryLocation W32047543001 @default.
- W3204754300 hasRelatedWork W10054795 @default.
- W3204754300 hasRelatedWork W1113861 @default.
- W3204754300 hasRelatedWork W12330032 @default.
- W3204754300 hasRelatedWork W15306364 @default.
- W3204754300 hasRelatedWork W18298229 @default.
- W3204754300 hasRelatedWork W21219867 @default.
- W3204754300 hasRelatedWork W2524492 @default.
- W3204754300 hasRelatedWork W2775817 @default.
- W3204754300 hasRelatedWork W4785343 @default.
- W3204754300 hasRelatedWork W9736235 @default.
- W3204754300 isParatext "false" @default.
- W3204754300 isRetracted "false" @default.
- W3204754300 magId "3204754300" @default.
- W3204754300 workType "article" @default.