Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204759097> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W3204759097 endingPage "S573" @default.
- W3204759097 startingPage "S572" @default.
- W3204759097 abstract "Armed oncolytic viruses (OV) are a promising modality for the treatment of solid tumors. OVs exert their antitumoral activity through a selective replication in tumor cells and expression of therapeutic molecules. The use of OV in the clinic is limited by the intra-tumoral route. TG6002 is an OV of the Vaccinia Copenhagen strain, with two deletions in key viral genes to enhance replication selectivity in tumor cells, and expressing FCU1, an enzyme converting 5-FC into 5-FU. As part of a dose-escalation phase I trial, we showed that TG6002 was distributed and delivered its payload in tumor after IV administration in patients with advanced GI carcinomas." @default.
- W3204759097 created "2021-10-11" @default.
- W3204759097 creator A5004938649 @default.
- W3204759097 creator A5006299989 @default.
- W3204759097 creator A5026178459 @default.
- W3204759097 creator A5027371764 @default.
- W3204759097 creator A5029162469 @default.
- W3204759097 creator A5046669159 @default.
- W3204759097 creator A5049933270 @default.
- W3204759097 creator A5052935862 @default.
- W3204759097 creator A5053069942 @default.
- W3204759097 creator A5089622240 @default.
- W3204759097 date "2021-09-01" @default.
- W3204759097 modified "2023-09-27" @default.
- W3204759097 title "486P Bioavailability and activity of oncolytic virus TG6002 after intravenous administration in patients with advanced gastrointestinal carcinomas" @default.
- W3204759097 doi "https://doi.org/10.1016/j.annonc.2021.08.1006" @default.
- W3204759097 hasPublicationYear "2021" @default.
- W3204759097 type Work @default.
- W3204759097 sameAs 3204759097 @default.
- W3204759097 citedByCount "0" @default.
- W3204759097 crossrefType "journal-article" @default.
- W3204759097 hasAuthorship W3204759097A5004938649 @default.
- W3204759097 hasAuthorship W3204759097A5006299989 @default.
- W3204759097 hasAuthorship W3204759097A5026178459 @default.
- W3204759097 hasAuthorship W3204759097A5027371764 @default.
- W3204759097 hasAuthorship W3204759097A5029162469 @default.
- W3204759097 hasAuthorship W3204759097A5046669159 @default.
- W3204759097 hasAuthorship W3204759097A5049933270 @default.
- W3204759097 hasAuthorship W3204759097A5052935862 @default.
- W3204759097 hasAuthorship W3204759097A5053069942 @default.
- W3204759097 hasAuthorship W3204759097A5089622240 @default.
- W3204759097 hasBestOaLocation W32047590971 @default.
- W3204759097 hasConcept C104317684 @default.
- W3204759097 hasConcept C140704245 @default.
- W3204759097 hasConcept C159047783 @default.
- W3204759097 hasConcept C2522874641 @default.
- W3204759097 hasConcept C2781356689 @default.
- W3204759097 hasConcept C40767141 @default.
- W3204759097 hasConcept C502942594 @default.
- W3204759097 hasConcept C55493867 @default.
- W3204759097 hasConcept C71924100 @default.
- W3204759097 hasConcept C82210918 @default.
- W3204759097 hasConcept C86803240 @default.
- W3204759097 hasConceptScore W3204759097C104317684 @default.
- W3204759097 hasConceptScore W3204759097C140704245 @default.
- W3204759097 hasConceptScore W3204759097C159047783 @default.
- W3204759097 hasConceptScore W3204759097C2522874641 @default.
- W3204759097 hasConceptScore W3204759097C2781356689 @default.
- W3204759097 hasConceptScore W3204759097C40767141 @default.
- W3204759097 hasConceptScore W3204759097C502942594 @default.
- W3204759097 hasConceptScore W3204759097C55493867 @default.
- W3204759097 hasConceptScore W3204759097C71924100 @default.
- W3204759097 hasConceptScore W3204759097C82210918 @default.
- W3204759097 hasConceptScore W3204759097C86803240 @default.
- W3204759097 hasLocation W32047590971 @default.
- W3204759097 hasOpenAccess W3204759097 @default.
- W3204759097 hasPrimaryLocation W32047590971 @default.
- W3204759097 hasRelatedWork W1975917770 @default.
- W3204759097 hasRelatedWork W1982789518 @default.
- W3204759097 hasRelatedWork W2020035378 @default.
- W3204759097 hasRelatedWork W2029677668 @default.
- W3204759097 hasRelatedWork W2030010353 @default.
- W3204759097 hasRelatedWork W2057384762 @default.
- W3204759097 hasRelatedWork W2081994579 @default.
- W3204759097 hasRelatedWork W2113321923 @default.
- W3204759097 hasRelatedWork W2900908558 @default.
- W3204759097 hasRelatedWork W2989604007 @default.
- W3204759097 hasVolume "32" @default.
- W3204759097 isParatext "false" @default.
- W3204759097 isRetracted "false" @default.
- W3204759097 magId "3204759097" @default.
- W3204759097 workType "article" @default.