Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204803605> ?p ?o ?g. }
Showing items 1 to 51 of
51
with 100 items per page.
- W3204803605 abstract "Sensing and responding to changes in NaCl concentration in hypersaline environments is vital for cell survival. We have identified and characterized key components of the high-osmolarity glycerol (HOG) signal transduction pathway, which is crucial in sensing hypersaline conditions in the extremely halotolerant black yeast Hortaea werneckii and in the obligate halophilic fungus Wallemia ichthyophaga. Both organisms were isolated from solar salterns, their predominating ecological niche. The identified components included homologous proteins of both branches involved in sensing high osmolarity (SHO1 and SLN1) and the homologues of mitogen-activated protein kinase module (MAPKKK Ste11, MAPKK Pbs2, and MAPK Hog1). Functional complementation of the identified gene products in S. cerevisiae mutant strains revealed some of their functions. Structural protein analysis demonstrated important structural differences in the HOG pathway components between halotolerant/halophilic fungi isolated from solar salterns, salt-sensitive S. cerevisiae, the extremely salt-tolerant H. werneckii, and halophilic W. ichthyophaga. Known and novel gene targets of MAP kinase Hog1 were uncovered particularly in halotolerant H. werneckii. Molecular studies of many salt-responsive proteins confirm unique and novel mechanisms of adaptation to changes in salt concentration." @default.
- W3204803605 created "2021-10-11" @default.
- W3204803605 creator A5086442713 @default.
- W3204803605 date "2021-10-01" @default.
- W3204803605 modified "2023-09-24" @default.
- W3204803605 title "Sensing and Responding to Hypersaline Conditions and the HOG Signal Transduction Pathway in Fungi Isolated from Hypersaline Environments: <em>Hortaea werneckii</em> and <em>Wallemia ichthyophaga</em>" @default.
- W3204803605 doi "https://doi.org/10.20944/preprints202110.0026.v1" @default.
- W3204803605 hasPublicationYear "2021" @default.
- W3204803605 type Work @default.
- W3204803605 sameAs 3204803605 @default.
- W3204803605 citedByCount "0" @default.
- W3204803605 crossrefType "posted-content" @default.
- W3204803605 hasAuthorship W3204803605A5086442713 @default.
- W3204803605 hasBestOaLocation W32048036051 @default.
- W3204803605 hasConcept C30992042 @default.
- W3204803605 hasConcept C523546767 @default.
- W3204803605 hasConcept C54355233 @default.
- W3204803605 hasConcept C55493867 @default.
- W3204803605 hasConcept C59822182 @default.
- W3204803605 hasConcept C62478195 @default.
- W3204803605 hasConcept C80642116 @default.
- W3204803605 hasConcept C86803240 @default.
- W3204803605 hasConcept C89423630 @default.
- W3204803605 hasConcept C95444343 @default.
- W3204803605 hasConceptScore W3204803605C30992042 @default.
- W3204803605 hasConceptScore W3204803605C523546767 @default.
- W3204803605 hasConceptScore W3204803605C54355233 @default.
- W3204803605 hasConceptScore W3204803605C55493867 @default.
- W3204803605 hasConceptScore W3204803605C59822182 @default.
- W3204803605 hasConceptScore W3204803605C62478195 @default.
- W3204803605 hasConceptScore W3204803605C80642116 @default.
- W3204803605 hasConceptScore W3204803605C86803240 @default.
- W3204803605 hasConceptScore W3204803605C89423630 @default.
- W3204803605 hasConceptScore W3204803605C95444343 @default.
- W3204803605 hasLocation W32048036051 @default.
- W3204803605 hasOpenAccess W3204803605 @default.
- W3204803605 hasPrimaryLocation W32048036051 @default.
- W3204803605 hasRelatedWork W1410299698 @default.
- W3204803605 hasRelatedWork W1566367761 @default.
- W3204803605 hasRelatedWork W1998184313 @default.
- W3204803605 hasRelatedWork W2060590186 @default.
- W3204803605 hasRelatedWork W2092602079 @default.
- W3204803605 hasRelatedWork W2438620851 @default.
- W3204803605 hasRelatedWork W2477786741 @default.
- W3204803605 hasRelatedWork W2791904028 @default.
- W3204803605 hasRelatedWork W3199867087 @default.
- W3204803605 hasRelatedWork W3209469768 @default.
- W3204803605 isParatext "false" @default.
- W3204803605 isRetracted "false" @default.
- W3204803605 magId "3204803605" @default.
- W3204803605 workType "article" @default.